Real word effects in phonological treatment for word retrieval

单词检索语音处理中的真实单词效果

• 批准号: 8898733
• 负责人: DIANE L. KENDALL
• 金额: --
• 依托单位: VA PUGET SOUND HEALTHCARE SYSTEM
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8898733
• 关键词: Adult; Aftercare; Alexia; Annual Reports; Anomia; Aphasia; Auditory; Award; Binding; Caregivers; Caring; Child; Communication; Communities; Controlled Study; Data; Databases; Development; Enrollment; Equipment and Supplies; Feedback; Frequencies; Funding; Goals; Growth; Hawthorne Effect; Health; High Prevalence; Home environment; Hour; Impairment; Individual; Institutional Review Boards; Intervention; Investigation; Knowledge; Knowledge acquisition; Language; Language Therapy; Lead; Learning; Left; Lesion; Life; Longitudinal Studies; Maintenance; Manuscripts; Measures; Methods; Modeling; Motivation; Names; Neighborhoods; Outcome Measure; Participant; Pathologist; Patient Education; Patients; Performance; Phase; Pilot Projects; Positioning Attribute; Principal Investigator; Probability; Problem Solving; Process; Production; Publications; Randomized; Randomized Controlled Trials; Reading; Receptive aphasia; Recruitment Activity; Rehabilitation Research; Rehabilitation therapy; Relative (related person); Reliability of Results; Reporting; Research; Research Personnel; Research Training; Residual state; Retrieval; Semantics; Site; Societies; Speech; Stimulus; Stroke; Structure; System; Tactile; Testing; Time; Training; Treatment Efficacy; Treatment Protocols; Veterans; Videotape; Visual; Vocabulary; Work; World Health Organization; Writing; aphasia rehabilitation; aphasic; base; career; clinical practice; cost; cost effective; density; design; disability burden; dosage; efficacy testing; follow-up; human subject; improved; lexical; lexical processing; meetings; novel; patient population; phase 2 study; phonology; primary outcome; programs; research and development; research study; response; sound; standard measure; therapy development; treatment program

DESCRIPTION (provided by applicant): The purpose of this Merit Review proposal is to continue Phase II development of a phonologic (e.g. sound) based treatment program for word retrieval deficits in aphasia. The most common feature of aphasia is impairment in ability to name objects. The traditional treatment approach to this problem is to train aphasic patients by showing them pictures of objects and asking them to say or repeat the name of that object several times. Controlled studies have shown that this approach may be effective, however generalization is typically limited to just the words trained. The mechanisms underlying generalization are not well understood. Because generalization is so limited with "naming therapies", there currently exists no viable means of training patients on the full corpus of words (perhaps several thousand) they are likely to need in daily life. Two approaches might be taken to solving this problem: (1) develop cost effective means for providing training on several thousand words; and (2) develop alternative training methods, e.g., phonological therapy, that could potentially generalize widely. This systematic line of research focuses on the latter. A Phase I pilot study funded by VA RR&D (PI: Kendall) showed that by applying treatment to the level of the phonologic system (e.g. sounds), reading and spoken word production improved in individuals with aphasia (Kendall et al, 2003). Phase II work (VA RR&D PI: Kendall) extended the Phase I research by 1) comparing the experimental phonologic treatment to a control treatment and 2) refining the experimental treatment in terms of a homogeneous patient population and increasing the frequency and intensity of treatment. Results showed significant treatment and generalization effects in the phonologic treatment group were superior to the semantic group (Kendall et al, 2008). While only preliminary, these results warrant the need for a larger investigation of this approach to the rehabilitation of aphasia. Thus, the purpose of this proposal is to continue Phase II development of a phonologic based treatment program for word retrieval deficits in aphasia. This project involves a longitudinal study to assess treatment and maintenance effects in 30 subjects with left hemisphere lesions and aphasia associated with impaired word retrieval with the goal of completing therapy and 3-month follow-up.

描述（由申请人提供）： 该优点审查提案的目的是继续开发基于语音的基于语音的治疗计划，以解决失语中的单词检索缺陷。失语症的最常见特征是命名对象的能力受损。解决此问题的传统治疗方法是通过向他们展示对象的图片并要求他们说或重复该物体的名称多次来训练失语症患者。对照研究表明，这种方法可能是有效的，但是概括通常仅限于受过训练的单词。概括的基本机制尚不清楚。由于“命名疗法”的概括是如此限制，因此目前没有可行的手段对他们在日常生活中可能需要的全部单词（也许是几千）培训患者。可以采用两种方法来解决这个问题：（1）为提供数千个单词提供培训的成本有效手段； （2）开发替代训练方法，例如语音疗法，可能会广泛推广。这项系统的研究线集中在后者上。 VA RR＆D（PI：Kendall）资助的I期试点研究表明，通过将治疗方法应用于语音系统水平（例如，声音），失语症患者的阅读和口语产生改善（Kendall等，2003）。第二阶段的工作（VA RR＆D PI：Kendall）通过1）将实验性语音处理与对照处理进行比较以及2）根据均匀的患者人群进行了实验治疗，并增加治疗频率和强度。结果表明，语音处理组的显着治疗和概括效应优于语义组（Kendall等，2008）。虽然仅初步，但这些结果需要对这种康复的方法进行更大的调查。因此，该提案的目的是继续开发基于语音的治疗计划，以解决失语症中的单词检索缺陷。该项目涉及一项纵向研究，以评估30名受试者的治疗和维持效果，左半球病变和与单词检索受损相关的失语症，目的是完成治疗和3个月的随访。

项目成果

Effects of Phonomotor Treatment on discourse production.

语音运动治疗对话语产生的影响。

• DOI: 10.1080/02687038.2018.1512080
• 发表时间: 2019
• 期刊: Aphasiology
• 影响因子: 2
• 作者: Silkes,JoAnnP;Fergadiotis,Gerasimos;Pompon,RebeccaHunting;Torrence,Janaki;Kendall,DianeL
• 通讯作者: Kendall,DianeL