Real word effects in phonological treatment for word retrieval

单词检索语音处理中的真实单词效果

• 批准号: 8898733
• 负责人: DIANE L. KENDALL
• 金额: --
• 依托单位: VA PUGET SOUND HEALTHCARE SYSTEM
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8898733
• 关键词: Adult; Aftercare; Alexia; Annual Reports; Anomia; Aphasia; Auditory; Award; Binding; Caregivers; Caring; Child; Communication; Communities; Controlled Study; Data; Databases; Development; Enrollment; Equipment and Supplies; Feedback; Frequencies; Funding; Goals; Growth; Hawthorne Effect; Health; High Prevalence; Home environment; Hour; Impairment; Individual; Institutional Review Boards; Intervention; Investigation; Knowledge; Knowledge acquisition; Language; Language Therapy; Lead; Learning; Left; Lesion; Life; Longitudinal Studies; Maintenance; Manuscripts; Measures; Methods; Modeling; Motivation; Names; Neighborhoods; Outcome Measure; Participant; Pathologist; Patient Education; Patients; Performance; Phase; Pilot Projects; Positioning Attribute; Principal Investigator; Probability; Problem Solving; Process; Production; Publications; Randomized; Randomized Controlled Trials; Reading; Receptive aphasia; Recruitment Activity; Rehabilitation Research; Rehabilitation therapy; Relative (related person); Reliability of Results; Reporting; Research; Research Personnel; Research Training; Residual state; Retrieval; Semantics; Site; Societies; Speech; Stimulus; Stroke; Structure; System; Tactile; Testing; Time; Training; Treatment Efficacy; Treatment Protocols; Veterans; Videotape; Visual; Vocabulary; Work; World Health Organization; Writing; aphasia rehabilitation; aphasic; base; career; clinical practice; cost; cost effective; density; design; disability burden; dosage; efficacy testing; follow-up; human subject; improved; lexical; lexical processing; meetings; novel; patient population; phase 2 study; phonology; primary outcome; programs; research and development; research study; response; sound; standard measure; therapy development; treatment program

DESCRIPTION (provided by applicant): The purpose of this Merit Review proposal is to continue Phase II development of a phonologic (e.g. sound) based treatment program for word retrieval deficits in aphasia. The most common feature of aphasia is impairment in ability to name objects. The traditional treatment approach to this problem is to train aphasic patients by showing them pictures of objects and asking them to say or repeat the name of that object several times. Controlled studies have shown that this approach may be effective, however generalization is typically limited to just the words trained. The mechanisms underlying generalization are not well understood. Because generalization is so limited with "naming therapies", there currently exists no viable means of training patients on the full corpus of words (perhaps several thousand) they are likely to need in daily life. Two approaches might be taken to solving this problem: (1) develop cost effective means for providing training on several thousand words; and (2) develop alternative training methods, e.g., phonological therapy, that could potentially generalize widely. This systematic line of research focuses on the latter. A Phase I pilot study funded by VA RR&D (PI: Kendall) showed that by applying treatment to the level of the phonologic system (e.g. sounds), reading and spoken word production improved in individuals with aphasia (Kendall et al, 2003). Phase II work (VA RR&D PI: Kendall) extended the Phase I research by 1) comparing the experimental phonologic treatment to a control treatment and 2) refining the experimental treatment in terms of a homogeneous patient population and increasing the frequency and intensity of treatment. Results showed significant treatment and generalization effects in the phonologic treatment group were superior to the semantic group (Kendall et al, 2008). While only preliminary, these results warrant the need for a larger investigation of this approach to the rehabilitation of aphasia. Thus, the purpose of this proposal is to continue Phase II development of a phonologic based treatment program for word retrieval deficits in aphasia. This project involves a longitudinal study to assess treatment and maintenance effects in 30 subjects with left hemisphere lesions and aphasia associated with impaired word retrieval with the goal of completing therapy and 3-month follow-up.

描述(由申请人提供)： 这项功绩评估建议的目的是继续第二阶段开发基于语音(例如声音)的治疗失语症单词提取缺陷的计划。失语症最常见的特征是命名物体的能力受损。对这个问题的传统治疗方法是训练失语症患者，向他们展示物体的图片，并要求他们说出或重复该物体的名字几次。对照研究表明，这种方法可能是有效的，但泛化通常仅限于训练过的单词。泛化背后的机制还没有被很好地理解。由于“命名疗法”的泛化非常有限，目前还没有可行的方法来训练患者在日常生活中可能需要的完整语料库(可能是数千个)。解决这一问题可以采取两种方法：(1)开发具有成本效益的方法来提供数千个单词的培训；(2)开发可广泛推广的替代培训方法，例如语音疗法。这一系统的研究路线侧重于后者。由VA RR&D(PI：Kendall)资助的一项第一阶段试点研究表明，通过对语音系统(例如声音)水平的治疗，失语症患者的阅读和口语产出得到改善(Kendall等人，2003)。第二阶段工作(VA RR&D PI：Kendall)扩展了第一阶段研究，通过1)将实验音学治疗与对照治疗进行比较，以及2)根据同质患者群体的条件改进实验治疗，并增加治疗的频率和强度。结果显示，语音治疗组的显著治疗和泛化效果优于语义组(Kendall等，2008)。虽然这只是初步的结果，但这些结果证明有必要对失语症康复的这种方法进行更大规模的调查。因此，这项建议的目的是继续第二阶段的发展，以音系学为基础的治疗失语症的单词提取缺陷的计划。该项目包括一项纵向研究，以评估30名左脑损害和失语症患者的治疗和维持效果，这些患者与单词提取障碍相关，目标是完成治疗和3个月的随访。

项目成果

Effects of Phonomotor Treatment on discourse production.

语音运动治疗对话语产生的影响。

• DOI: 10.1080/02687038.2018.1512080
• 发表时间: 2019
• 期刊: Aphasiology
• 影响因子: 2
• 作者: Silkes,JoAnnP;Fergadiotis,Gerasimos;Pompon,RebeccaHunting;Torrence,Janaki;Kendall,DianeL
• 通讯作者: Kendall,DianeL