Investigating a novel genetic regulator of cardiac rhythm

研究心律的新型遗传调节剂

• 批准号: nhmrc : 1123456
• 负责人: Dr Kelly Smith
• 金额: $ 38.01万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/investigating-novel-genetic-cardiac-rhythm/947173
• 关键词: Investigating; novel; genetic; regulator; cardiac

Cardiac arrhythmias affect approximately 5% of the population and have a high association with sudden death. Whilst the cause of cardiac arrhythmia is complex, we know that genetic mutations play a role however we don't know all the genes important for cardiac rhythm. It is imperative that we identify all the genes in this process, so we can determine which mutations cause arrhythmia. We have identified a new gene that causes cardiac arrhythmia and seek to understand how it functions.

心律失常影响约5%的人群，并与猝死高度相关。虽然心律失常的原因是复杂的，但我们知道基因突变发挥了作用，但我们不知道所有对心律重要的基因。我们必须确定这个过程中的所有基因，这样我们就可以确定哪些突变会导致心律失常。我们已经发现了一种导致心律失常的新基因，并试图了解它的功能。