Gender-Specific Research in Emergency Care: Investigate, Understand and Translate

紧急护理中的特定性别研究：调查、理解和转化

• 批准号: 8720207
• 负责人: Basmah Safdar
• 金额: $ 1万
• 依托单位: SOCIETY FOR ACADEMIC EMERGENCY MEDICINE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8720207
• 关键词: Accident and Emergency department; Acute; Address; Affect; Algorithms; Alteplase; American; Attention; Basic Science; Biological; Biology; Caring; Centers for Disease Control and Prevention (U.S.); Clinical; Clinical Research; Clinical Trials; Collaborations; Consensus; Critical Care; Data; Development; Devices; Diagnosis; Diagnostic Imaging; Discrimination; Disease; Disease Management; Emergency Care; Emergency Department Physician; Emergency Medicine; Emergency Situation; Encapsulated; Epilepsy; Female; Gender; Gender Issues; Genetic; Headache; Health; Healthcare; Heart Arrest; Hour; Human; Human Biology; Individual; Institute of Medicine (U.S.); Intervention; Journals; Knowledge; Laboratories; Lead; Medicine; Mission; Modality; Neurologic; Neurological emergencies; Neurological outcome; Neurologist; Outcome; Pain; Patient Representative; Patients; Phase; Play; Policy Maker; Positioning Attribute; Prevention; Process; Reporting; Research; Research Infrastructure; Research Personnel; Resources; Resuscitation; Role; Science; Science Policy; Scientist; Seizures; Sex Characteristics; Site; Stroke; Texas; Therapeutic; Time; Time Study; Translating; Traumatic Brain Injury; Treatment outcome; United States; United States Agency for Healthcare Research and Quality; United States National Institutes of Health; Visit; Woman; Work; acute stroke; base; clinical Diagnosis; cost effective; improved; interdisciplinary collaboration; male; medical specialties; men; multidisciplinary; neurological recovery; outreach; preclinical study; public health relevance; response; sex; social; symposium; working group

Gender medicine is the rapidly growing field of medicine that aims to provide equitable, safe, and cost- effective care for both male and female patients. While "sex" is the preferred term in basic science research, in this application we have used the term "gender" - referring to the socially constructed biological roles of an individual based on his or her XX or XY status - as it is more commonly used by clinicians. The focus of this field of medicine is gender-based biological differences in addition to the social mechanisms that influence the manifestation, diagnosis, and management of disease conditions. Significant gaps in gender-specific treatment and outcomes are evident in several spheres of emergency care especially neurological emergencies and resuscitation. These include cardiac arrest, traumatic brain injury and neurological recovery, acute stroke, seizures, headaches as well as in resource utilization such as diagnostic imaging or device selection. Emergency departments (ED) form the core recruitment site and laboratory for clinical research trials studying such time-sensitive conditions. With a 24-hour presence in the ED and with access to patients in these spheres, emergency physicians play an ideal role in leading gender-specific clinical studies for acute neurological care and also serve as vital partners for interdisciplinary collaboration. The 2014 Academic Emergency Medicine (AEM) consensus conference, "Gender Specific Research in Emergency Care - Investigate, Understand and Translate How Gender Affects Patient Outcomes" will address this void by assembling clinicians, researchers, policy-makers, and basic and clinical scientists from multiple specialties to understand and investigate gender-related disparities in clinical outcomes of neurological emergencies. The conference will focus on high volume and resource-consuming ED visits with a particular focus on neurological emergencies. Specific aims of the workgroup are to: 1) Summarize and consolidate current data to improve our understanding of gender-specific research for neurological emergencies and identify critical gender-related gaps in knowledge in emergency care, 2) Create a research agenda that advances gender- specific research in the prevention, diagnosis, and management of neurological emergencies, and 3) Build a multinational interdisciplinary consortium to translate, disseminate and study gender medicine of acute neurological emergencies. A designated issue of AEM and invited specialty journals will disseminate the scientific summary, research agenda, and conference proceedings, as well as original research related to gender issues. The three-year planning phase of this conference will culminate in a one-day conference on May 13, 2014 in Dallas, Texas. The collaborative network established through this conference will also create an infrastructure for continued meaningful national collaborations on gender-specific research in emergency care.

性别医学是快速增长的医学领域，旨在提供公平，安全和成本 - 男性和女性患者有效护理。而“性”是基础科学研究的首选术语，但 该应用程序我们使用了“性别”一词 - 指的是社会建构的生物学作用 基于他或她的XX或XY身份的个人 - 因为临床医生更常用。重点 医学领域是基于性别的生物学差异，除了影响的社会机制 疾病状况的表现，诊断和管理。性别特定治疗的差距很大 在急诊护理的几个领域，尤其是神经系统紧急情况和 复苏。其中包括心脏骤停，创伤性脑损伤和神经系统康复，急性中风， 癫痫发作，头痛以及资源利用（例如诊断成像或设备选择）。 急诊部（ED）构成了研究临床研究试验的核心招聘现场和实验室 这种时间敏感的条件。在ED中有24小时的存在，并在其中访问患者 球体，急诊医师在领导性别特异性临床研究中起着理想的作用 神经护理，还充当跨学科合作的重要伙伴。 2014年学者 急诊医学（AEM）共识会议，“急诊疗法的性别特定研究 - 调查，理解和翻译性别如何影响患者的结果” 组装临床医生，研究人员，政策制定者以及来自多个专业的基础和临床科学家 了解和研究神经系统紧急情况的临床结果中与性别相关的差异。 会议将重点介绍大量和资源消费的ED访问，特别关注 神经系统紧急情况。工作组的具体目的是：1）总结并巩固当前数据 提高我们对针对神经系统紧急情况的性别特定研究的理解并确定关键 与性别相关的紧急护理知识差距，2）创建一个研究议程，使性别发展 关于神经系统紧急情况的预防，诊断和管理的具体研究，以及3）建立一个 跨国跨学科财团翻译，传播和研究急性的性别医学 神经系统紧急情况。指定的AEM和邀请专业期刊将传播 科学摘要，研究议程和会议论文集，以及与 性别问题。这次会议的三年计划阶段将在为期一天的会议上 2014年5月13日在得克萨斯州达拉斯。通过这次会议建立的协作网络也将 创建一个基础架构，以持续有意义的全国性合作在性别特定研究中 紧急护理。

项目成果

Emergency Medicine Gender-specific Education.

• DOI: 10.1111/acem.12545
• 发表时间: 2014-12
• 期刊: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
• 作者: Ashurst JV;McGregor AJ;Safdar B;Weaver KR;Quinn SM;Rosenau AM;Goyke TE;Roth KR;Greenberg MR
• 通讯作者: Greenberg MR

Funding mechanisms for gender-specific research: proceedings from a panel discussion at the 2014 Academic Emergency Medicine consensus conference.

针对特定性别研究的资助机制：2014 年学术急诊医学共识会议小组讨论的记录。

• DOI: 10.1111/acem.12522
• 发表时间: 2014
• 期刊: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
• 作者: Safdar,Basmah;Greenberg,MarnaR;Anise,Ayodola;Brown,Jeremy;Conwit,Robin;Filart,Rosemarie;Scott,Jane;Choo,EstherK
• 通讯作者: Choo,EstherK

Gender-specific research on mental illness in the emergency department: current knowledge and future directions.

急诊科精神疾病的性别研究：当前知识和未来方向。

• DOI: 10.1111/acem.12524
• 发表时间: 2014
• 期刊: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
• 作者: Ranney,MeganL;Locci,Natalie;Adams,EricaJ;Betz,Marian;Burmeister,DavidB;Corbin,Ted;Dalawari,Preeti;Jacoby,JeanneL;Linden,Judith;Purtle,Jonathan;North,Carol;Houry,DebraE
• 通讯作者: Houry,DebraE

The intersecting roles of violence, gender, and substance use in the emergency department: a research agenda.

急诊科中暴力、性别和药物使用的交叉作用：研究议程。

• DOI: 10.1111/acem.12525
• 发表时间: 2014
• 期刊: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
• 作者: Choo,EstherK;Benz,Madeline;Rybarczyk,Megan;Broderick,Kerry;Linden,Judith;Boudreaux,EdwinD;Ranney,MeganL
• 通讯作者: Ranney,MeganL

Gender-specific Regulatory Challenges to Product Approval: a panel discussion.

产品批准面临的特定性别监管挑战：小组讨论。

• DOI: 10.1111/acem.12531
• 发表时间: 2014
• 期刊: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine
• 作者: McGregor,AlysonJ;Barr,Helen;Greenberg,MarnaR;Safdar,Basmah;Wildgoose,Peter;Wright,DavidW;Hollander,JuddE
• 通讯作者: Hollander,JuddE