Multidisciplinary Neonatal Training Grant

描述（由申请人提供）：本申请要求为二年级和三年级新生儿科研究员提供2个医师培训职位，这将使他们能够发展在新生儿科学术领域独立研究所需的知识、理解和技能。两个学术研究方向将提供给学员，每个方向将与包含必修课程的特定课程相关联：轨道一：基础研究，医师-科学家-（实验室研究指导和研究生基础科学研究）；第二分会：临床研究，医师-科学家（以患者为导向的转化研究），包括硕士课程。这个项目有两个研究方向，分别位于新生儿科和吉恩和乔治·布伦利，小新生儿研究所。科室师资队伍包括临床研究医师6人（其中硕士研究生3人）；2名基础研究医师；基础科学博士7人。NPRI包括128名研究人员，其中75%是NIH资助的，并利用杜克大学的学术实力和深度来支持发育生物学、临床科学和卫生保健研究方面的正式培训。NPRI的外部资助研究目前支持4个广泛的研究领域：1)早期心肺面部发育；2)新生儿肺部发育/修复；3)发育神经和干细胞生物学；胎儿和新生儿的神经损伤和修复；4)与NICHD新生儿研究网络、杜克临床研究所、普拉特工程学院和基因组科学与政策研究所合作进行新生儿转化临床研究。申请的资金将为新生儿科奖学金的研究年提供关键支持，该奖学金目前在杜克大学医学中心培训8名研究员。独特的研究培训项目有其独立的轨道，将提供严格的结构化学习经验，根据个人的需求和兴趣量身定制，每个研究员都有一位资深科学家作为导师。在该项目的5名T-32培训毕业生中，所有人都是学术机构的教师（杜克大学3人，UT-Houston 1人，UC-Irvine 1人）。其中三人完成了硕士课程，两人获得了联邦资助（K23和AHRQ）。

DESCRIPTION (provided by applicant): This application requests support for 2 physician training positions for 2nd and 3rd year neonatology fellows, which will allow them to develop the knowledge, understanding and skills needed to pursue independent research careers in academic neonatology. Two academic research paths will be available to trainees, and each track will be associated with a specific curriculum containing required course work: Track I: Basic Research, Physician-Scientist - (laboratory research mentorship and graduate basic science studies); and Track II: Clinical Research, Physician-Scientist (patient-oriented translational research) including Masters programs. This program with its two research tracks resides within the Division of Neonatology and the Jean & George Brumley, Jr. Neonatal-Research Institute. The Division faculty includes 6 clinical research physician-scientists (3 are Masters trained); 2 basic research physician-scientists; and 7 PhD focused on basic science research. The NPRI includes 128 investigators, 75% of whom are NIH funded, and draws upon the academic strength and depth found across Duke University needed to support formal training in developmental biology, clinical sciences and health care research. Extramurally funded research within the NPRI currently supports 4 broad areas of investigation: 1) early cardiocraniofacial development; 2) neonatal lung development/repair; 3) developmental neural and stem cell biology; and neural injury and repair in the fetus and neonate; and 4) translational clinical neonatal research in conjunction with the NICHD Neonatal Research Network, the Duke Clinical Research Institute, the Pratt School of Engineering, and Institute for Genome Science and Policy. The requested funds will provide critical support for the research years of the neonatology fellowship, which currently trains 8 fellows at Duke University Medical Center. The unique research training program with its separate Tracks will provide a rigorous structured learning experience tailored to the needs and interests of the individual fellow, each fellow working with a senior scientist serving as mentor. Of the 5 T-32 trainee graduates of this program, all are faculty at academic institutions (3 at Duke, 1 at UT-Houston, and 1 at UC-Irvine). Three have completed a Masters program and two have received federal funding (K23 and AHRQ).