MULTICENTER NETWORK OF NEONATAL INTENSIVE CARE UNITS

杜克大学新生儿-围产期医学部的这项申请的目的是参与合作多中心新生儿研究网络，该网络的目标是通过大型多中心合作试验调查新生儿护理中的治疗策略。虽然规模相对较小，但该司对循证医学及其在开发转化研究项目方面的工作的热情从教师参与和在过去和现在项目中的领导作用中可见一斑，这些项目包括NIH赞助的HIM研究、表面活性物质试验、最近的一氧化氮(CINRGI)试验以及围产期窒息的头部冷却方案。为了支持我们的临床和基础科学工作，该司建立了新生儿-围产期研究所(NPRI)，该研究所跨越传统的部门和专业线，鼓励以新生儿-围产期为重点的合作转化性研究。新生儿-围产期医学部高度致力于临床研究，最近还获得了院长颁发的“转化医学奖”。杜克临床研究所为两名教员和一名研究员提供的临床研究硕士学位的支持进一步证明了我们的承诺。意识到我们研究工作的一个重要组成部分必须处理我们医疗保健的社会和经济方面，我们开发了创造性的方法来评估医疗保健经济学。这些战略为杜克保健系统(新生儿医学司)带来了显著的积极财政收益。在杜克大学，医院和科室之间随后的合作关系加强了医院的财务状况，并为科室的研究机构(NPRI)提供了大量医院支持的研究基金。在整个网络中测试杜克大学开发的工具、方法和分析方法可能会令人感兴趣，并允许验证我们的发现。北卡罗来纳州的研究三角地区正在扩大，因此，杜克大学的医疗保健网络现在包括3个托儿所。整个系统包括6000次交付(杜克大学3200次)，842次ICN先天入学，以及另外324次可用于网络研究的交通工具。该司设有一个全面的多学科后续诊所，以整体的方式处理患者，关注营养，并以强烈的肺部和神经学为重点。该诊所与社区服务建立了良好的联系，并与社区服务进行了协作。

The objective of this application by the Division of Neonatal-Perinatal Medicine at Duke University is to participate in the Cooperative Multicenter Neonatal Research Network whose goal is to investigate treatment strategies in the care of the neonate through large multicenter cooperative trials. Although relatively small, the Division's enthusiasm for evidenced-based medicine and its work in developing translational research projects is evidenced by faculty participation and leadership roles in past and present projects, such as the NIH sponsored HIM study, surfactant trials, a recent nitric oxide (CINRGI) trial, and the head cooling protocol for perinatal asphyxia. In an effort to support our clinical and basic science efforts, the Division has established the Neonatal-Perinatal Research Institute (NPRI) that cuts across traditional departmental and specialty lines to encourage collaborative translational research with a neonatal- perinatal focus. The Division of Neonatal-Perinatal Medicine is highly committed to clinical research and is a recent recipient of the Dean's "Award for Translational Medicine". Further evidence of our commitment is illustrated by the Division's support for two faculty and one fellow working towards a master's in clinical research, offered by the Duke Clinical Research Institute. Realizing that a strong component of our research effort must deal with the social and economic aspects of our care, we have developed creative approaches to evaluating health care economics. These strategies have resulted in significant positive financial gain for the Duke Health System a Division of Neonatal Medicine. At Duke, the ensuing partnership between hospital and Division has lead to a strengthening of hospital financial health and a resultant substantial hospital supported research endowment to the Division's research institute (NPRI). Testing the tools, approaches and analytical methods developed at Duke across the Network may be of interest and allow for verification of our findings. The Research Triangle area of North Carolina is growing and as a result, the Duke Health Care network now includes 3 nurseries. The system as a whole includes 6000 deliveries (3200 at Duke), 842 ICN inborn admissions and an additional 324 transports available for Network studies. The Division houses a comprehensive multidisciplinary follow-up clinic that approaches the patient in a holistic fashion with attention to nutrition and with strong pulmonary and neurologic focus. The Clinic is well connected to and works collaboratively with community services.