IGF::OT::IGF - METABOLITE STANDARDS SYNTHESIS CENTERS; PP 7/15/13-7/14/14; FY13;

IGF::OT::IGF - 代谢物标准品合成中心；

• 批准号: 8895138
• 负责人: MARY TANGA
• 金额: $ 95.33万
• 依托单位: SRI INTERNATIONAL
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-15 至 2015-07-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8895138
• 关键词: Address; Area; Citric Acid Cycle; Consultations; Contractor; Contracts; Disease; Funding; Goals; Label; Metabolic Pathway; Pathway interactions; Production; Research; Services; Sterols; Techniques; United States; United States National Institutes of Health; amino acid metabolism; good laboratory practice; lipid metabolism; metabolomics; new therapeutic target; programs

The NIH Common Fund has identified Metabolomics as one of the cross-cutting research areas that can potentially have wide ranging impact on our understanding of disease mechanisms and identifying novel therapeutic targets. In order to increase metabolomics research capacity in the United States, the NIH Common Fund has developed a multi-component Program to help overcome current challenges. This requirement is aimed at addressing one of the challenges, namely the lack of high quality and authentic standards for identification, characterization and quantitation of metabolites visualized through currently available analytical techniques. The goal is to increase the repertoire of chemically identifiable metabolites to achieve greater coverage of the metabolome.

NIH普通基金已将代谢组学确定为可能对我们对疾病机制的理解和识别新型治疗靶标具有广泛影响的横切研究领域之一。为了提高美国的代谢组学研究能力，NIH Common Fund制定了一项多组分计划，以帮助克服当前的挑战。该要求旨在应对挑战之一，即缺乏通过当前可用的分析技术可视化的代谢物的识别，表征和定量的高质量和真实标准。目的是增加化学可识别的代谢产物的曲目，以实现对代谢组的更大覆盖率。