IGF::OT::IGF - METABOLITE STANDARDS SYNTHESIS CENTERS; PP 7/15/13-7/14/14; FY13;

IGF::OT::IGF - 代谢物标准品合成中心；

• 批准号: 8895138
• 负责人: MARY TANGA
• 金额: $ 95.33万
• 依托单位: SRI INTERNATIONAL
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-15 至 2015-07-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8895138
• 关键词: Address; Area; Citric Acid Cycle; Consultations; Contractor; Contracts; Disease; Funding; Goals; Label; Metabolic Pathway; Pathway interactions; Production; Research; Services; Sterols; Techniques; United States; United States National Institutes of Health; amino acid metabolism; good laboratory practice; lipid metabolism; metabolomics; new therapeutic target; programs

The NIH Common Fund has identified Metabolomics as one of the cross-cutting research areas that can potentially have wide ranging impact on our understanding of disease mechanisms and identifying novel therapeutic targets. In order to increase metabolomics research capacity in the United States, the NIH Common Fund has developed a multi-component Program to help overcome current challenges. This requirement is aimed at addressing one of the challenges, namely the lack of high quality and authentic standards for identification, characterization and quantitation of metabolites visualized through currently available analytical techniques. The goal is to increase the repertoire of chemically identifiable metabolites to achieve greater coverage of the metabolome.

美国国立卫生研究院共同基金已经确定代谢组学作为交叉研究领域之一，可以潜在地对我们对疾病机制的理解和确定新的治疗靶点产生广泛的影响。为了提高美国的代谢组学研究能力，美国国立卫生研究院共同基金开发了一个多组件计划来帮助克服当前的挑战。这一要求旨在解决一个挑战，即缺乏高质量和真实的标准，通过现有的分析技术来识别、表征和定量代谢物。目标是增加化学可识别代谢物的曲目，以实现代谢物组更大的覆盖范围。