Sensory Transduction

感觉传导

• 批准号: 8719730
• 负责人: Miriam B Goodman
• 金额: $ 3.26万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-03-01 至 2015-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8719730
• 关键词: Academia; Animal Model; Anosmia; Award; Behavior; Biological; Biological Models; Biology; Blindness; Boston; Budgets; Burn injury; Caenorhabditis elegans; California; Cells; Chemicals; Chemistry; Collaborations; Commit; Communities; Complex; Disease; Ensure; Environment; Esthesia; Ethnic group; Event; Exposure to; Food; Fostering; Funding; Gender; Genome; Goals; Government; Hearing; Human; Impairment; Industry; Influentials; Institution; International; Laboratories; Life; Marines; Massachusetts; Medicine; Mission; Modality; Molecular; Mus; Nationalities; Nervous system structure; Numbness; Organism; Pain; Participant; Partner in relationship; Pediatric Hospitals; Perception; Pharmacologic Substance; Physiology; Postdoctoral Fellow; Proteins; Public Health; Recruitment Activity; Research; Research Personnel; Science; Scientist; Sensory; Signal Transduction; Smell Perception; Societies; Staging; Stimulus; Structure; Students; Taste Perception; Technology; Temperature; Touch sensation; Travel; Underrepresented Minority; United States National Institutes of Health; Universities; Vision; Wood material; Work; abstracting; base; career; deafness; design; experience; graduate student; improved; insight; interest; meetings; new technology; offspring; posters; programs; public health relevance; relating to nervous system; sensory mechanism; sensory neuropathy; sensory stimulus; sensory system; success; symposium; therapeutic target

DESCRIPTION (provided by applicant): Our senses provide us with the information that we need to perform all the essential functions of life: navigate the world, avoid danger, find food, choose mates and nurture our offspring. Each sensory modality is tuned to a specific set of stimuli; this tuning sets the limits of our sensory experience. Thus understanding how sensory cells detect and transduce sensory stimuli is critical to understanding how the nervous system responds to the environment to generate appropriate behaviors and perceptions. Moreover, disruption of sensory signaling in diseases ranging from blindness to deafness to insensitivity to pain can be devastating for humans. Despite ample evidence of shared molecular components and shared principles for transforming sensory input to neural signals across the senses, researchers investigating distinct senses rarely have opportunities to interact directly. With new technologies emerging at an ever- increasing rate, the timely sharing of information is needed to greatly accelerate research in sensory biology. The goal of this conference proposal is to assemble leading researchers across all sensory modalities (vision, smell, taste, touch, temperature, pain) and create an event designed to spark new collaborations among established and emerging investigators as well as graduate students and postdoctoral fellows. The conference, entitled "Sensory Transduction", will be the 68th Annual Symposium of the Society of General Physiologists (SGP), a conference that has long been recognized as a pioneering and high- impact meeting for physiologists, cell biologists, and biophysicists. The venue, the campus of the Marine Biological Laboratory in Woods Hole, MA, is a magical place that affords participants with an intimate environment and ample opportunities to share scientific insight in both formal and informal settings.

描述（由申请人提供）：我们的感官为我们提供了执行所有生命基本功能所需的信息：导航世界，避免危险，寻找食物，选择配偶和养育我们的后代。每一种感觉形态都被调整到一组特定的刺激;这种调整设定了我们感官体验的极限。因此，了解感觉细胞如何检测和处理感觉刺激对于理解神经系统如何对环境做出反应以产生适当的行为和感知至关重要。此外，从失明到耳聋到对疼痛不敏感的疾病中的感觉信号中断对人类来说可能是毁灭性的。尽管有充分的证据表明，将感官输入转换为神经信号的分子成分和原则是相同的，但研究不同感官的研究人员很少有机会直接互动。随着新技术的不断涌现，需要及时共享信息，以大大加快感官生物学的研究。本次会议提案的目标是召集所有感官模式（视觉，嗅觉，味觉，触觉，温度，疼痛）的领先研究人员，并创建一个旨在激发现有和新兴研究人员以及研究生和博士后研究员之间新合作的活动。该会议名为“感觉传导”，将是普通生理学家学会（SGP）的第68届年度研讨会，该会议长期以来被公认为生理学家，细胞生物学家和生物药理学家的开创性和高影响力会议。地点是位于马萨诸塞州伍兹霍尔的海洋生物实验室校园，这是一个神奇的地方，为与会者提供了一个亲密的环境和充分的机会，在正式和非正式的场合分享科学见解。