Research Career Development Core

项目摘要(见说明)：RCDC的首要任务是培养老龄研究的未来领导者，重点是加州大学洛杉矶分校的主题--预防弱势群体中的疾病和残疾：翻译方法。RCDC将促进针对这一主题的未来研究领导者的发展，特别是能够将关于老年人健康、疾病、独立性和残疾的临床见解与包括老年学在内的基础科学进展相结合的领导者，以开发更好的干预措施，以保持健康和独立性。RCDC的目标是1)确定最有潜力成为未来老龄化研究领导者的初级教师，以我们的OAIC主题为重点，获得三年职业发展奖(CDA)；2)促进这些初级科学家的研究培训和职业生涯；3)为CDA获奖者提供支持性环境，最大限度地提高成功培训、研究进展和最终职业成功的可能性；4)包括与每个受训者需求相关的翻译科学原则和方法的培训；以及5)为加州大学洛杉矶分校初级教师提供与老龄化相关的研究指导资源。为了实现这些目标，加州大学洛杉矶分校的RCDC还将向少数族裔CDA候选人进行外展，寻找经过临床培训的候选人，并关注少数族裔人口在研究中的代表性的重要性。1年级的4名考生正在进行与加州大学洛杉矶分校的主题相关的研究。乔丹·莱克是一名传染病专家，他正在研究慢性炎症加速艾滋病毒感染者衰老过程的机制。朱迪思·卡罗尔博士是一位健康心理学家和心理神经免疫学家，他的工作重点是将睡眠作为一种模型，以确定社会、情感、环境和行为因素影响与年龄相关疾病、免疫衰老和加速衰老易感性的生物机制。Lee Jennings医学博士是一名老年病学家，他正在研究艾滋病毒老年患者的卫生保健需求，目的是改善艾滋病毒老年患者的护理质量、获得机会和提供服务。医学博士Gerardo Moreno是一名家庭医生，他正在研究对患有慢性病的弱势老年人进行适当的药物管理，并进行干预，包括决策支持和临床药剂师咨询，以改善初级保健环境中的药物管理。

PROJECT SUMMARY (See instructions): The overarching mission of the RCDC is to develop future leaders in aging research, focused in the area of UCLA's theme, Preventing Disease and Disability in Vulnerable Populations: a Translational Approach. The RCDC will promote the development of future research leaders who address this theme, particularly leaders who can integrate clinical insights regarding health, disease, independence, and disability in older adults with knowledge of advances in the basic sciences, including gerontology, to develop better interventions to maintain health and independence. The goals of the RCDC are to 1) identify junior faculty who have the greatest potential as future leaders in aging research to receive three year career development awards (CDAs), focused on our OAIC theme; 2) foster the research training and careers of these junior scientists; 3) provide a supportive environment for CDA awardees that maximizes the likelihood of successful training, research progress and ultimate career success; 4) Include training in translational science principles and methods relevant to each trainee's needs; and 5) serve as a resource in aging-related research mentorship for UCLA junior faculty. In meeting these goals, the UCLA RCDC will also conduct outreach to minority CDA candidates, seek out candidates who have been clinically trained, and be attentive to the importance of minority populations' representation in research. The 4 candidate CDAs for Year 1 are conducting research related to UCLA's theme. Jordan Lake, MD, is an infectious disease specialist who is examining mechanisms by which chronic inflammation accelerates aging processes in HIV-infected persons. Judith Carroll, PhD, is a health psychologist and psychoneuroimmunologist whose work focuses on using sleep as a model to identify the biological mechanisms through which social, emotional, environmental and behavioral factors influence vulnerability for age-related disease, immunosenescence, and accelerated aging. Lee Jennings, MD, is a geriatrician who is examining the health care needs of older adults with HIV with the aims of improving the quality, access to and delivery of care to older persons with HIV. Gerardo Moreno, MD, is a family physician who is examining appropriate medication management among vulnerable older adults with chronic conditions and interventions including decision support, and clinical pharmacist consultations to improve medication management in primary care settings.