Research Career Development Core

项目摘要（参见说明）：RCDC 的首要任务是培养老龄化研究的未来领导者，重点关注加州大学洛杉矶分校的主题“预防弱势群体疾病和残疾：转化方法”。 RCDC 将促进解决这一主题的未来研究领导者的发展，特别是能够将有关老年人健康、疾病、独立和残疾的临床见解与包括老年学在内的基础科学进展知识相结合的领导者，以制定更好的干预措施来维持健康和独立。 RCDC 的目标是 1) 确定最有潜力成为老龄化研究未来领导者的初级教师，以获得三年职业发展奖 (CDA)，重点关注我们的 OAIC 主题； 2）促进这些初级科学家的研究培训和职业生涯； 3) 为 CDA 获奖者提供支持性环境，最大限度地提高成功培训、研究进展和最终职业成功的可能性； 4) 包括与每个学员的需求相关的转化科学原理和方法的培训； 5) 为加州大学洛杉矶分校的初级教师提供与老龄化相关的研究指导资源。在实现这些目标的过程中，加州大学洛杉矶分校 RCDC 还将对少数族裔 CDA 候选人进行外展，寻找经过临床培训的候选人，并关注少数族裔在研究中代表性的重要性。第一年的 4 名候选 CDA 正在进行与 UCLA 主题相关的研究。医学博士乔丹·莱克 (Jordan Lake) 是一位传染病专家，他正在研究慢性炎症加速艾滋病毒感染者衰老过程的机制。朱迪思·卡罗尔博士是一位健康心理学家和心理神经免疫学家，其工作重点是使用睡眠作为模型来确定社会、情感、环境和行为因素影响年龄相关疾病、免疫衰老和加速衰老的脆弱性的生物机制。 Lee Jennings 医学博士是一位老年病学家，他正在研究感染艾滋病毒的老年人的医疗保健需求，目的是提高感染艾滋病毒的老年人的质量、获得和提供护理服务。 Gerardo Moreno 医学博士是一名家庭医生，他正在研究患有慢性病的弱势老年人的适当药物管理和干预措施，包括决策支持和临床药剂师咨询，以改善初级保健机构的药物管理。

PROJECT SUMMARY (See instructions): The overarching mission of the RCDC is to develop future leaders in aging research, focused in the area of UCLA's theme, Preventing Disease and Disability in Vulnerable Populations: a Translational Approach. The RCDC will promote the development of future research leaders who address this theme, particularly leaders who can integrate clinical insights regarding health, disease, independence, and disability in older adults with knowledge of advances in the basic sciences, including gerontology, to develop better interventions to maintain health and independence. The goals of the RCDC are to 1) identify junior faculty who have the greatest potential as future leaders in aging research to receive three year career development awards (CDAs), focused on our OAIC theme; 2) foster the research training and careers of these junior scientists; 3) provide a supportive environment for CDA awardees that maximizes the likelihood of successful training, research progress and ultimate career success; 4) Include training in translational science principles and methods relevant to each trainee's needs; and 5) serve as a resource in aging-related research mentorship for UCLA junior faculty. In meeting these goals, the UCLA RCDC will also conduct outreach to minority CDA candidates, seek out candidates who have been clinically trained, and be attentive to the importance of minority populations' representation in research. The 4 candidate CDAs for Year 1 are conducting research related to UCLA's theme. Jordan Lake, MD, is an infectious disease specialist who is examining mechanisms by which chronic inflammation accelerates aging processes in HIV-infected persons. Judith Carroll, PhD, is a health psychologist and psychoneuroimmunologist whose work focuses on using sleep as a model to identify the biological mechanisms through which social, emotional, environmental and behavioral factors influence vulnerability for age-related disease, immunosenescence, and accelerated aging. Lee Jennings, MD, is a geriatrician who is examining the health care needs of older adults with HIV with the aims of improving the quality, access to and delivery of care to older persons with HIV. Gerardo Moreno, MD, is a family physician who is examining appropriate medication management among vulnerable older adults with chronic conditions and interventions including decision support, and clinical pharmacist consultations to improve medication management in primary care settings.