Investigating the role of novel heterochromatin and centromere proteins in chromosome segregation

在细胞分裂过程中，遗传物质的均匀分裂是必不可少的，这样遗传物质就不会丢失或获得。这个过程是由一组复杂的蛋白质控制的，这些蛋白质复制基因组，保持其结构完整性，并将一个拷贝均匀地分配给每个子细胞。本研究旨在研究在单细胞酵母模型系统以及人类和小鼠细胞中新发现的这一过程所需的蛋白质的功能。

The equal division of genetic material during cell division is essential so that genetic material is not lost or gained. This process is controlled by a complex array of proteins that replicate the genome, maintain its structural integrity, and equally distribute one copy to each daughter cell. This research aims to study the functions of newly identified proteins required for this process in a single cell yeast model-system and in human and mouse cells.