Post Graduate Training in Pediatric Oncology

描述(由申请人提供)：科罗拉多大学丹佛分校(UCD)和儿童医院(TCH)的儿科血液学/肿瘤学奖学金项目拥有超过35年的杰出历史。在过去的5年里，随着向新建的安舒茨医学院(AMC)的过渡，培训计划受益匪浅。儿科肿瘤学实验室在2004-2005学年搬迁到AMC上扩大的、最先进的研究空间。2007年9月，TCH还搬迁到AMC，成为一家占地144万平方英尺的新医院，其中有294张床位，为落基山脉地区七个州的患者提供服务。因此，在该项目的历史上，儿科肿瘤学实习生第一次被安排在一个医疗园区，其中包括TCH、科罗拉多大学医院、UCD医学院和科罗拉多生物科学公园。在过渡到新校区期间，儿科肿瘤学奖学金计划和教职员工的规模也有了显着增长，现在有25名临床学院，每年有4名新研究员进入3年制奖学金计划。与此同时，T32研究培训学院已扩大到30名成员，增加了研究员在儿科肿瘤学方面进行基于实验室的、转化性或临床研究的机会。T32培训学院代表了广泛的科学学科，包括细胞周期控制和信号、转录调控和剪接、病毒学和免疫学。还增加了在临床研究和转译肿瘤学方面具有专门知识的培训学院，包括为药物开发确定新的生物靶点。该培训计划最初是在2000年用这笔T32赠款资助的，目前提交的是这一支持的第二次竞争性续签。由于具有广泛的临床经验、儿童医院杰出的临床声誉以及新的研究机会，自1993年以来，奖学金申请者在质量和对学术事业的奉献方面一直在不断提高。事实上，在过去5年的奖学金计划中，15名毕业生中有13名现在是教职员工，自2007年以来的所有毕业生都是教职员工。奖学金的最低期限为三年。第一年几乎完全用于临床培训，而第二年和第三年至少有80%的时间用于研究。目前有12名研究员参加该计划，他们都以前完成了儿科住院医生的培训，其中8人目前正在接受超过他们第一个临床研究员年的研究培训。这项提案旨在为那些选择在奖学金的第二年和随后几年继续与儿科肿瘤学相关研究的MD研究员提供资金，并选择致力于儿科癌症研究的博士后研究员。因此，无论是历史还是最近的发展，都标志着这一培训计划是全国最好的培训计划之一。

DESCRIPTION (provided by applicant): The Pediatric Hematology/Oncology Fellowship Program at the University of Colorado Denver (UCD) and The Children's Hospital (TCH) has a distinguished history spanning over 35 years. Over the last 5 years, the Training Program has benefited significantly with the transition to the newly built Anschutz Medical Campus (AMC). The Pediatric Oncology laboratories relocated in the 2004-2005 academic year into expanded, state-of-the art research space on the AMC. In September 2007, TCH also relocated onto the AMC into a new 1.44 million square feet hospital that includes 294 beds and serves patients from seven states in the Rocky Mountain region. Thus, for the first time in the history of the program, Pediatric Oncology trainees are located on one medical campus which includes TCH, University of Colorado Hospital, UCD School of Medicine, and the Colorado Biosciences Park. The Pediatric Oncology Fellowship Program and faculty also grew significantly in size during this transition to the new campus and now consist of 25 Clinical Faculty with 4 new fellows entering the 3-year Fellowship Program annually. In parallel, the T32 Research Training Faculty has been expanded to 30 members, increasing the opportunities given to fellows to perform laboratory-based, translational or clinical research in pediatric oncology. The T32 Training Faculty represent a broad range of scientific disciplines including cell cycle control and signaling, transcriptional regulation and splicing, virology, and immunology. Training Faculty with specific expertise in clinical research and translational oncology, including identification of novel biologic targets for drug development, have also been added. The Training Program was initially funded in 2000 with this T32 grant, and the current submission is the second competitive renewal of this support. Because of the breadth of the clinical experience, the outstanding clinical reputation of the Children's Hospital, and the new research opportunities available, fellowship candidates since 1993 have consistently increased in quality and dedication to an academic career. Indeed, 13 of 15 graduates in the last 5 years of the Fellowship Program are now in academic faculty, and all graduates since 2007 have academic faculty positions. The minimal fellowship duration is three years. The first year is devoted almost exclusively to clinical training, while at least 80% of time during years 2 and 3 is devoted to research. Currently there are 12 fellows in the Program, all of whom have previously completed their Pediatric residencies, with 8 currently in research training beyond their first clinical fellowship year. This proposal seeks funding for those MD fellows who elect to pursue research related to Pediatric Oncology in the second and subsequent years of the fellowship, and select PhD post-doctoral fellows committed to a career in pediatric cancer research. Both history and recent developments thus mark this training program as one of the best in the nation.