Interdisciplinary Cerebrovascular Diseases Training Program in South America

描述(由申请者提供)：这项修订后的NCD-LIFESPAN申请名为“Ictus：南美跨学科脑血管培训计划”，其总体目标是通过确定中风的环境、生活方式和宿主风险因素，降低秘鲁脑血管疾病的发病率和死亡率，并与政府和学术机构合作制定政策，以减少通过该计划确定的人口水平的风险因素。为了实现这一目标，我们提出了以下具体目标：1)为20名在脑血管神经病学和康复医学方面有前途的年轻医生提供严格的临床研究方法培训--长期目标是培养一支内科临床科学家队伍，他们将对脑血管疾病的流行病学和病因学进行独立研究，并最终在秘鲁开发和领导独立研究计划；2)为这20名秘鲁受训人员资助临床研究项目，以提供临床研究实践经验，并为未来的拨款申请获得试点数据；以及3)在学术机构和秘鲁卫生部之间建立联盟，以促进制定和实施政策战略，将研究成果转化为与脑血管疾病相关的改善公共卫生。这些具体目标将通过短期、中期和长期培训相结合的方式实现，重点是在佩鲁阿纳卡耶塔诺大学(UPCH)和华盛顿大学(UW)进行硕士学位培训，以及在华盛顿大学进行为期三个月的流行病学研究方法综合培训，并具有中风管理和康复医学方面的实践经验。我们还建议在脑血管和慢性病流行病学、手稿和赠款准备以及负责任的研究方面举办短期培训讲习班；导师培训课程将与讲习班同时举行。这一拟议培训计划的最大优势是成功地合作了先前在秘鲁的威斯康星大学和加州大学伯克利分校的培训计划；在西雅图和秘鲁担任导师的世界知名临床研究人员、神经流行病学家和中风专家；以及在秘鲁发展良好的研究地点。通过Fogarty以前资助的培训计划培训的庞大秘鲁同事网络提供了一个绝佳的机会，可以利用现有的研究和培训专业知识来扩大能力，以应对秘鲁日益加重的慢性疾病，特别是脑血管疾病的负担。

DESCRIPTION (provided by applicant): The overarching goal of this revised NCD-LIFESPAN application entitled "ICTuS: Interdisciplinary Cerebrovascular Training program in South America" is to reduce morbidity and mortality of cerebrovascular disease in Peru through identifying environmental, lifestyle and host risk factors for stroke and collaborate with governmental and academic institutions to develop policies to decrease population-level risk factors identified through this program. To attain this goal we propose the following specific aims: 1) provide rigorous clinical research methodological training for 20 promising young physicians in cerebrovascular neurology and rehabilitation medicine - with the long-term goal of developing a cadre of physician clinician scientists who will conduct independent research on the epidemiology and etiology of cerebrovascular diseases and eventually develop and lead independent research programs in Peru; 2) fund mentored clinical research projects for these 20 Peruvian trainees to provide practical experiences in clinical research and obtain pilot data for future grant applications; and 3) build alliances between academic institutions and the Peruvian Ministry of Health to facilitate development and implementation of policy strategies to translate research findings into improved public health relevant to cerebrovascular disease. These specific aims will be addressed through a combination of short, medium and long-term training, with an emphasis on master's degree training at the Universidad Peruana Cayetano Heredia (UPCH) and the University of Washington (UW) and three-month Comprehensive training in epidemiologic research methods at the UW with practical experience in stroke management and rehabilitation medicine. We also propose short training workshops in cerebrovascular and chronic diseases epidemiology, manuscript and grant preparation, and responsible conduct of research; mentor training courses will be held concomitantly with workshops. The greatest strengths of this proposed training program are the successful collaborations of prior UW/UPCH training programs in Peru; world- renowned clinical researchers, neuroepidemiologists, and stroke experts in Seattle and Peru who will serve as mentors; and well-developed study sites in Peru. The vast network of Peruvian colleagues trained through prior Fogarty-funded training programs provides an outstanding opportunity to leverage existing research and training expertise to expand capacity to address the increasing burden of chronic diseases, specifically cerebrovascular disease, in Peru.