Immunology and Infectious Diseases

描述（由申请人提供）：部门。哈佛公共卫生学院（HSPH）生物科学部（DBS）免疫学和传染病研究所（DIID）由一支强大的科学家团队组成，他们致力于研究与免疫反应以及传染病的生物学、流行病学和免疫学相关的问题。DBS成立于1993年，是一个伞状结构，涵盖免疫学和传染病，复杂疾病的遗传学，癌细胞生物学，环境健康和营养等领域的生物实验室科学。的博士公共卫生生物科学课程（BPH）位于HSPH，由艺术与科学研究生院提供。这个博士前培训补助竞争性更新申请将支持BPH学生谁选择在免疫学和传染病系的教师实验室工作。BPH计划提供了一个独特的机会，培养领导干部谁拥有专业知识，在生物研究的各个领域和流行病学和生物统计学的广泛的跨学科知识。越来越明显的是，流行病学家和实验室科学家之间的密切互动最能促进疾病预防方面的进展，实验室发现和流行病学观察以迭代的方式相互作用，推动这两个领域的研究。我们的培训记录在此期间的补助金一直是优秀的出版记录和支持的博士前学生的职业道路证明。六处可以细分为三个主要领域，免疫学，寄生虫和其他感染的分子生物学，和病毒学。这些部门的教师有PI，劳里Glimcher，淋巴细胞中的基因表达;巴里布鲁姆，莎拉财富和埃里克鲁宾，结核病;蒂芙尼霍恩，炎症，温迪加勒特，宿主-宿主相互作用;戴恩沃思，疟疾，利什曼病;芭芭拉伯利，T。cruzi，疟疾; Manoj Duraisingh，疟疾; Myron埃塞克斯，Phyllis Kanki，人类免疫缺陷病毒。HMS主要任命的三名教员是Judy Lieberman和Joseph Sodrowski，HIV，l-Cheng Ho，细胞因子和Hidde Ploegh，MIT，病毒感染的细胞生物学。 相关性（见说明）：基本的生物学和流行病学发现必须置于广泛的社会背景下。该方案鼓励在实验室研究和实地工作之间建立更密切联系方面有着互补利益的科学家之间积极合作，所有这些都着眼于开发创新的预防方法。免疫学和传染病领域，以及HSPH免疫学和传染病系的研究生非常适合这种互动。

DESCRIPTION (provided by applicant): The Dept. of Immunology and Infectious Diseases (DIID) in the Division of Biologic Sciences (DBS) at the Harvard School of Public Health (HSPH) comprises a strong team of accomplished scientists who work on problems related to the immune response and to the biology, epidemiology and immunology of infectious diseases. DBS, established in 1993, is an umbrella structure that encompasses the biologic laboratory sciences in the areas of Immunology and Infectious Diseases, the Genetics of Complex Diseases, Cancer Cell Biology, Environmental Health, and Nutrition. The Ph.D. Program in Biological Sciences in Public Health (BPH) is located at HSPH and is offered by the Graduate School of Arts and Sciences. This predoctoral training grant competitive renewal application would support BPH students who choose to work in laboratories of faculty members of the Department of Immunology and Infectious Diseases. The BPH program provides a unique opportunity for training a cadre of leaders who possess expertise in the individual fields of biological research and a broad interdisciplinary knowledge of epidemiology and biostatistics. It has become increasingly evident that progress in disease prevention is optimally promoted by a close interaction between epidemiologists and laboratory scientists, where laboratory discoveries and epidemiological observations interact in an iterative manner to advance research in both fields. Our training record in this grant period has been excellent as evidenced by the publication record and career paths of the predoctoral students supported. The Dept. can be subdivided into three major areas, Immunology, Molecular Biology of Parasitic and Other Infections, and Virology. Faculty members in these Divisions are the PI, Laurie Glimcher, gene expression in lymphocytes; Barry Bloom, Sarah Fortune and Eric Rubin, tuberculosis; Tiffany Horng, inflammation, Wendy Garrett, host-commensal interactions; Dyann Wirth, malaria, leishmaniasis; Barbara Burleigh, T. cruzi, malaria; Manoj Duraisingh, malaria; Myron Essex, Phyllis Kanki, human immunodeficiency virus. Three faculty members with primary appointments at HMS are Judy Lieberman and Joseph Sodrowski, HIV, l-Cheng Ho, cytokines and Hidde Ploegh, MIT, cell biology of viral infections. RELEVANCE (See instructions): Basic biological and epidemiological discoveries must be placed in a wide social context. This program encourages active collaboration among scientists who share complementary interests in developing closer linkages between laboratory research and field work- all with an eye to developing innovative approaches to prevention. The field of immunology and infectious diseases, and the graduate students in the Department of Immunology and Infectious Diseases at HSPH is ideally suited for this Interaction.