Infectious Diseases and Child Health in Pakistan Research Training Program.

巴基斯坦传染病和儿童健康研究培训计划。

• 批准号: 8927751
• 负责人: Walter A. Orenstein
• 金额: $ 23.99万
• 依托单位: AGA KHAN UNIVERSITY (PAKISTAN)
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-01 至 2018-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8927751
• 关键词: 5 year old; Affect; Area; Centers for Disease Control and Prevention (U.S.); Cessation of life; Child; Child Mortality; Child health care; Childhood; Collaborations; Communicable Diseases; Developing Countries; Development; Diarrhea; Disease; Epidemiology; Goals; Immunization Programs; Individual; Infection; Leadership; Measles; Mentors; Morbidity - disease rate; Neonatal; Newborn Infant; Pakistan; Pathogenesis; Pneumococcal vaccine; Pneumonia; Poliomyelitis; Public Health; Research; Research Methodology; Research Training; Rotavirus Vaccines; Structure; Training; Training Programs; Universities; Vaccines; Work; disorder control; improved; mortality; novel vaccines; pediatric department; programs; skills

DESCRIPTION (provided by applicant): Infectious diseases are the biggest killers of children in Pakistan, causing 60% of all child deaths under 5 years of age. Neonatal infections (15%), diarrheal illnesses (18%), and pneumonia (21%) cause over 50% of all child deaths in Pakistan (WHO). Pakistan also harbors the highest numbers of poliomyelitis cases in the world, threatening global eradication goals. Although the infectious morbidity and mortality is huge, until this Fogarty-supported program was established in 2007, Pakistan had no formal training programs in infectious diseases, and a tremendous shortage of individuals with the requisite skills to conduct independent research in infectious diseases affecting Pakistani children. The Department of Pediatrics and Child Health at the Aga Khan University in Karachi has a well-established research program relevant to improving child health and survival in developing countries. In collaboration with colleagues at Emory and CDC in Atlanta, AKU can offer unique training opportunities in infectious diseases to Pakistani trainees. The long-term aim is to prepare a cadre of individuals who will provide the evidence, leadership, and enthusiasm needed to reduce the burden of childhood infections of major public health importance in Pakistan and other developing countries. The Infectious Diseases and Child Health in Pakistan (IDCHIP) Research Training Program will provide opportunities for structured long- and short-term training (degree and non-degree course work and mentored research) with particular focus on (i) vaccine-preventable illnesses and, (ii) neonatal infections. Building research skills in thee two areas has particular relevance for infectious disease control and reducing infectious disease-related child mortality in Pakistan. Research training areas will include: polio eradication, sustainable introduction of new vaccines against diarrhea (rotavirus vaccine) and pneumonia (pneumococcal vaccines), measles elimination, optimizing immunization programs; and epidemiology, pathogenesis, and treatment of neonatal infections. Long-term graduate training will be conducted in Pakistan, with short-term training options at Emory and CDC utilized for advanced skills development. A larger group of trainees from Pakistan will also benefit from specialized training in research methodology and research management. Non-technical Summary: Pakistan has a very high burden of infectious disease-related child deaths as well as crippling diseases such as polio. This training program will equip individuals will research skills necessary to reduce the burden of infections in newborn babies and vaccine- preventable childhood illnesses.

描述（由申请人提供）：传染病是巴基斯坦儿童的最大杀手，导致 5 岁以下儿童死亡的 60%。新生儿感染 (15%)、腹泻病 (18%) 和肺炎 (21%) 导致巴基斯坦所有儿童死亡的 50% 以上 (WHO)。巴基斯坦也是世界上脊髓灰质炎病例数量最多的国家，威胁到全球根除脊髓灰质炎的目标。尽管传染病的发病率和死亡率很高，但在 2007 年福加蒂支持的这项计划建立之前，巴基斯坦没有正式的传染病培训计划，而且非常缺乏具备对影响巴基斯坦儿童的传染病进行独立研究所需技能的人员。卡拉奇阿加汗大学儿科和儿童健康系拥有一个完善的研究项目，旨在改善发展中国家的儿童健康和生存。 AKU 与埃默里大学和亚特兰大疾病预防控制中心的同事合作，可以为巴基斯坦学员提供独特的传染病培训机会。长期目标是培养一支骨干队伍，他们将提供所需的证据、领导力和热情，以减少对巴基斯坦和其他发展中国家具有重大公共卫生重要性的儿童感染负担。巴基斯坦传染病和儿童健康 (IDCHIP) 研究培训计划将提供结构化的长期和短期培训（学位和非学位课程以及指导研究）的机会，特别关注 (i) 疫苗可预防的疾病和 (ii) 新生儿感染。在这两个领域建立研究技能对于巴基斯坦的传染病控制和降低与传染病相关的儿童死亡率特别重要。研究培训领域将包括：根除脊髓灰质炎、持续推出新的腹泻疫苗（轮状病毒疫苗）和肺炎疫苗（肺炎球菌疫苗）、消除麻疹、优化免疫计划；以及新生儿感染的流行病学、发病机制和治疗。长期研究生培训将在巴基斯坦进行，并在埃默里大学和疾病预防控制中心进行短期培训，以培养高级技能。来自巴基斯坦的更多学员也将受益于研究方法和研究管理方面的专门培训。非技术摘要：巴基斯坦因传染病相关的儿童死亡以及脊髓灰质炎等严重疾病而承受着非常高的负担。该培训计划将为个人提供必要的研究技能，以减轻新生儿感染负担和疫苗可预防的儿童疾病。