The Brief Research in Aging and Interdisciplinary Neurosciences

描述（由申请人提供）：哥伦比亚大学医学中心神经病学系是多学科神经学研究的丰富场所，特别关注与衰老神经系统相关的疾病。在这项提案中，在衰老和跨学科神经科学（脑）计划的简要研究，我们已经制定了一个全面的方法来制定一个正式的研究计划，为博士前学生在生物医学，行为和临床研究的职业生涯早期。这项工作将通过为这些学生提供简短但密集的暑期研究培训经验来进行协作，并有可能随后开发纵向研究计划。研究培训将提供基础，行为和临床研究的机会，通过在基础神经科学，神经病理学，神经遗传学，神经心理学，中风，阿尔茨海默病和相关疾病，运动神经元疾病，帕金森病和相关疾病，癫痫等领域正在进行的研究，以及治疗这些疾病患者的神经学临床试验。此外，一个全面的结构化研究教育课程将在密集的研究经验的过程中给出，主题包括良好的临床实践，基本研究方法，介绍摘要作者和海报演示，并介绍统计概念和分析方法，以及流行病学和病理生理学的审查最常见的神经系统疾病与老龄化，因此可能会被研究。我们的机构有发展学术神经学家的任何地方世界上最强的跟踪记录，这样一个短期的，激烈的计划将建立在这个丰富的资源，通过动手介绍神经学研究，研究原则的全面审查，从而确保最好的机会，为这些学生在该领域发展研究事业。

DESCRIPTION (provided by applicant): The Department of Neurology at Columbia University Medical Center serves as a rich site for multidisciplinary neurological research, with particular focus on disorders associated with the aging nervous system. In this proposal, the Brief Research in Aging and Interdisciplinary Neurosciences (BRAIN) program, we have developed a comprehensive approach to develop a formal research program for predoctoral students early in developing careers in biomedical, behavioral and clinical research. The work will be collaboratively approached through brief but intensive mentored summer research training experiences for these students, with the potential for subsequent development of a longitudinal research program. The research training will provide opportunities in basic, behavioral and clinical research through ongoing research in the fields of basic neuroscience, neuropathology, neurogenetics, neuropsychology, stroke, Alzheimer disease and related disorders, motor neuron disease, Parkinson disease and related disorders, and epilepsy, as well as neurologic clinical trials treating patients with these disorders. In addition, a comprehensive structured research education curriculum will be given over the course of the intense research experience, with topics including good clinical practice, basic research methodologies, introductions to abstract authorship and poster presentations, and introduction of statistical concepts and approach to analyses, as well as epidemiologic and pathophysiologic reviews of the most common neurologic disorders associated with aging and thus likely to be studied. Our institution has the strongest track record of developing academic neurologists of anywhere worldwide, and such a short-term, intense program will build upon this wealth of resources through hands-on introductions to neurological research, comprehensive review of principles of research, and thus assure the best opportunity for these students to develop research careers in the field.