Overall Center Organization and Management Plan

临床和转化性研究基础设施网络(CTR-IN)的使命是增加 美国国立卫生研究院为临床和转化性研究提供数量、质量和资金，从而加快将科学发现转化为改善该地区健康的工作。我们将通过扩大地区范围来实现这一目标 由西部山区研究联盟发起的合作和伙伴关系(MWRC，请参阅 第1节中的详细说明)。行政核心及其将支持的两个监督机构--内部咨询委员会和外部咨询委员会--的努力将是推进这一使命。 我们的政策和程序将随着CTR-IN的发展而建立，然后根据经验和建议通过战略规划过程进行修改~以支持这一任务。 我们的IDEA-CTR项目将旨在解决在某些方面不寻常的问题，对于 这类企业；我们有许多不同的合作机构和计划，每个都有个人 优势和需求，分布在占美国整个陆地面积32.5%的地区。因此，我们的方案不能“一刀切”，它们必须灵活地从专业知识较强的机构中汲取资源，并在需要和最有效的地方提供资源和服务。 我们将通过在我们的内部咨询委员会中由一名高级行政人员(主管研究或同等级别的副总裁)代表参加的每个参与机构来实现这一点。一个主要的指导原则是，CTR-IN必须提供适当的资源和服务，以增加每个参与机构的临床和转化研究，而不是简单地使少数人受益。通过这种方法，我们将在参与临床转化研究的基础领域发展区域能力和实力，使我们能够利用这一独特的地区巨大的开放空间、稀少的聚居地和极端的环境，利用不同的人口、文化和环境对科学文献和临床实践做出有意义的贡献。

The mission of the Clinical and Translational Research Infrastructure Network (CTR-IN) is to increase the quantity, quality, and NIH funding of clinical and translational research thereby accelerating the translation of scientific discovery to improved health in the region. We will accomplish this by expanding the regional collaboration and partnerships initiated by the Mountain West Research Consortium (MWRC, please see detailed description in Section 1). The efforts of the Administrative Core, and the two supervisory bodies it will support: the Internal Advisory Committee and the External Advisory Committee, will be to further this mission. Our Policies and Procedures will be established ~ and then modified based on experience and advice through a strategic planning process as the CTR-IN evolves ~ to support this mission. Our IDeA-CTR project will be designed to address issues that are unusual, in some ways novel, for an enterprise of this kind; we have many and varied partner institutions and programs, each with individual strengths and needs, distributed across an area that represents 32.5% of the entire land mass of the US. Thus, our programs cannot be "one size fits all", they must be flexible in drawing resources from institutions where expertise is strong, and delivering resources and services where they are needed and can be most effective. We will achieve this by including every participating institution represented on our Internal Advisory Committee by a high level administrator (Vice President for Research level or equivalent). A primary guiding principle is that the CTR-IN must provide appropriate resources and services to increase clinical and translational research at each of the participating institutions, and that it not simply benefit a few. Through this approach we will develop regional competence and strength in areas fundamental to participation in clinical translational research at a level that will allow us to make meaningful contributions to the scientific literature and clinical practice leveraging the varied populations, cultures, and environments of this unique area of huge open spaces, sparse settlement, and environmental extremes.