Clinical and Translational Pilot Grant Program

概述和具体目标临床和转化试点补助金（CTPG）KCA的总体目标是在西部IDEA州的研究人员中建立临床和转化研究能力以及校外资助成功。解决西部地区IDEA州独特的区域健康问题的临床和转化研究主要在科学，文科和联合健康科学学院，公共卫生，护理，社会工作，心理学和相关课程的部门进行。然而，这些项目和计划往往资金不足，基础设施支持不足，受教师释放时间有限的限制，相互孤立，范围有限。一个全面的试点项目计划的支持将大大加快这些现有的努力，并使他们的独立校外资金的竞争力的水平。在过去的十年中，NIH资助的西部地区IDEA州的研究出现了前所未有的增长，这主要是由于COBRE和INBRE计划的支持。总体而言，这些COBRE和INBRE项目非常成功，但它们几乎完全集中在临床前研究上。几乎没有支持或基础设施可以帮助这些有才华的临床前研究人员进入转化研究。该KCA将实施一项计划，为试点赠款提供资金，支持可能导致独立NIH为临床和翻译研究者提供资金的项目。奖项将基于对科学价值的审查以及拟议研究与CTN-IN的使命的一致性。我们将征求关于主题的临床和转化研究项目的建议，包括但不限于西部地区IDEA州农村和弱势群体的健康问题和医疗保健服务。用于该计划的资金将转化为高收益的投资回报，因为研究人员开发跨学科合作并生成主要数据的证明，以加速成功的校外资助，最终加速医疗保健提供者采用变革性的健康相关发现。

Overview and Specific Aims The overall objective of the Clinical and Translational Pilot Grant (CTPG) KCA is to build clinical and translational research capacity and extramural funding success among researchers in the Western IDeA states. Clinical and Translational Research addressing the unique regional health issues of the Western Region IDeA states has been carried out mainly in colleges of science, liberal arts, and allied health sciences, in departments of public health, nursing, social work, psychology, and related programs. However, these projects and programs are often underfunded, struggling with inadequate infrastructure support, constrained by limited availability of faculty release time, isolated from one another, and limited in scope. Support from a comprehensive pilot project program will substantially accelerate these existing efforts and bring them to a level competitive for independent extramural funding. The last decade has seen an unprecedented increase in NIH-funded research within the Western Region IDeA states, largely due to the support from COBRE and INBRE programs. Overall, these COBRE and INBRE programs have been very successful, but they have been focused almost entirely on pre-clinical research. There has been little support or infrastructure available to help this talented cadre of pre-clinical investigators move into translational research. This KCA will implement a program to fund pilot grants supporting projects likely to lead to independent NIH funding for both clinical, and translational, investigators. Awards will be based on reviews of scientific merit and the alignment of the proposed research with the mission of the CTN-IN. We will solicit proposals for clinical and translational research projects on topics including, but not limited to, health issues and health care access among rural and vulnerable populations in the Western Region IDeA states. The funds devoted to this program will translate to a high yield return on investment as investigators develop interdisciplinary collaborations and generate proof of principal data to accelerate successful extramural grant funding, ultimately hastening the adoption of transformative health-related discoveries by health care providers.