Clinical and Translational Pilot Grant Program

临床和转化试点资助计划

• 批准号: 8876735
• 负责人: PARVESH KUMAR
• 金额: $ 18.71万
• 依托单位: UNIVERSITY OF NEVADA LAS VEGAS
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-01 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8876735
• 关键词: Address; Adoption; Allied Health Sciences; Applications Grants; Arts; Award; Basic Science; Biometry; Centers of Research Excellence; Clinical; Clinical Investigator; Clinical Research; Collaborations; Data; Development; Education; Ensure; Epidemiology; Extramural Activities; Faculty; Feedback; Funding; Funding Mechanisms; Grant; Health; Health Personnel; Health Services Accessibility; Healthcare; Institution; Investments; Lead; Link; Mentors; Mission; Monitor; Phase; Pilot Projects; Population; Psychology; Public Health Nurses; Public Health Nursing; Publications; Research; Research Activity; Research Design; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Rural Population; Science; Social Work; Time; Translating; Translational Research; United States National Institutes of Health; Vulnerable Populations; base; career; career development; college; human subject; interdisciplinary collaboration; pre-clinical; pre-clinical research; programs; research facility; success

Overview and Specific Aims The overall objective of the Clinical and Translational Pilot Grant (CTPG) KCA is to build clinical and translational research capacity and extramural funding success among researchers in the Western IDeA states. Clinical and Translational Research addressing the unique regional health issues of the Western Region IDeA states has been carried out mainly in colleges of science, liberal arts, and allied health sciences, in departments of public health, nursing, social work, psychology, and related programs. However, these projects and programs are often underfunded, struggling with inadequate infrastructure support, constrained by limited availability of faculty release time, isolated from one another, and limited in scope. Support from a comprehensive pilot project program will substantially accelerate these existing efforts and bring them to a level competitive for independent extramural funding. The last decade has seen an unprecedented increase in NIH-funded research within the Western Region IDeA states, largely due to the support from COBRE and INBRE programs. Overall, these COBRE and INBRE programs have been very successful, but they have been focused almost entirely on pre-clinical research. There has been little support or infrastructure available to help this talented cadre of pre-clinical investigators move into translational research. This KCA will implement a program to fund pilot grants supporting projects likely to lead to independent NIH funding for both clinical, and translational, investigators. Awards will be based on reviews of scientific merit and the alignment of the proposed research with the mission of the CTN-IN. We will solicit proposals for clinical and translational research projects on topics including, but not limited to, health issues and health care access among rural and vulnerable populations in the Western Region IDeA states. The funds devoted to this program will translate to a high yield return on investment as investigators develop interdisciplinary collaborations and generate proof of principal data to accelerate successful extramural grant funding, ultimately hastening the adoption of transformative health-related discoveries by health care providers.

概述和具体目标临床和转化性先导奖助金(CTPG)KCA的总体目标是在西方IDEA国家的研究人员中建立临床和转化性研究能力和外部资助成功。针对西部地区IDEA州独特的地区性健康问题的临床和翻译研究主要在理科、文科和相关卫生科学学院、公共卫生、护理、社会工作、心理学和相关项目中进行。然而，这些项目和计划往往资金不足，基础设施支持不足，教师释放时间有限，相互孤立，范围有限。综合试点项目计划的支持将大大加快这些现有的努力，并使其达到具有独立外部资金竞争力的水平。在过去的十年里，NIH资助的西部地区IDEA州的研究出现了前所未有的增长，这在很大程度上要归功于Cobre和INBRE项目的支持。总体而言，这些Cobre和INBRE计划非常成功，但它们几乎完全专注于临床前研究。几乎没有可用的支持或基础设施来帮助这支才华横溢的临床前研究人员进入转化性研究。该KCA将实施一项计划，为试点拨款提供资金，支持可能导致NIH为临床和转化性研究人员提供独立资金的项目。奖项将基于对科学价值和拟议研究与CTN-IN任务的一致性的审查。我们将就临床和转化性研究项目征求建议书，主题包括但不限于西部地区IDEA州农村和弱势人群的健康问题和医疗保健获得机会。投入该项目的资金将转化为高收益的投资回报，因为调查人员开展跨学科合作并生成主要数据证据，以加快成功的外部赠款资金，最终加速医疗保健提供者采用与健康相关的变革性发现。