Biomechanical Assessment of Femur Fracture in Pediatric Falls

儿童跌倒股骨骨折的生物力学评估

基本信息

  • 批准号:
    8838221
  • 负责人:
  • 金额:
    $ 7.47万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2014
  • 资助国家:
    美国
  • 起止时间:
    2014-04-14 至 2017-03-31
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): Child abuse is the leading cause of trauma-related fatalities in children less than four years of age. Children one year of age and younger are particularly at risk; approximately 1 out of every 48 children in this age group is a victim of abue or neglect. Cases of physical child abuse are commonly mistaken for accidental trauma. If the abuse goes unrecognized, the child is at risk for further, escalating injuries. An abused child returned to an unsafe home environment has up to an 80% risk for additional injury and up to a 30% risk of death. These repeat occurrences may be preventable through early detection of abuse. Fractures are early indicators of child abuse, but are also a common result of accidental trauma, such as household falls. Clinicians are often faced with the task of determining whether a child's injuries are the result of accidental causes or whether abuse should be suspected. Since household falls are a common false history given by caretakers to conceal abusive trauma, information regarding fracture potential in short-distance falls and specifically what type of fracture could result from different fall scenarios, may aid clinicians in distinguishing abusiv from accidental injuries, thus improving the accuracy of child abuse diagnoses. The purpose of this study is to provide objective, biomechanically-based information regarding femur fracture potential in short-distance falls. Three specific aims have been established to address this goal: (1) Describe femur loading (type and magnitude) associated with short-distance falls in young children, (2) Describe the likelihood of femur fractures in short-distance falls, (3) Develop an improved understanding of the influence of child-specific bone characteristics on fracture potential. This study will involve three primary methodological components. First, a CRABI 12-month-old anthropomorphic test device (ATD) will be modified to improve biofidelity of the lower extremities and instrumented to measure femur loads. Then, fall simulations will be conducted using the improved surrogate to determine femur loading characteristics. The final component involves development of a finite element model of a 12-month-old human child's femur. Femur loads from the ATD experiments will be reproduced in the finite element model. This will provide insight into fracture potential for the combined loading scenarios measured experimentally. Additionally, key parameters will be varied in the model as part of a sensitivity analysis to determine their effect on fracture potential. This will elucidate the effect of child-specific characteristics (such as bone density) on femur fracture potential. The outcomes from this study will provide an improved understanding of femur fracture potential in short-distance pediatric falls and lay the foundation for future work that will improve clinical assessments of injury and history compatibility. Additionally, though this study focuses on femur fracture potential, the approach used may serve as a model for future investigation of fracture potential in other bones.
描述(由申请人提供):虐待儿童是四岁以下儿童创伤相关死亡的主要原因。一岁及以下的儿童尤其危险;这一年龄段每48名儿童中约有1名是虐待或忽视的受害者。身体虐待儿童的案例通常被误认为是意外创伤。如果虐待行为没有被发现,孩子就有进一步受伤、不断升级的风险。被虐待的儿童回到不安全的家庭环境,有高达80%的额外伤害风险和高达30%的死亡风险。通过及早发现滥用行为,这些重复发生的情况是可以预防的。骨折是虐待儿童的早期迹象,但也是意外创伤的常见结果,如家庭摔倒。临床医生经常面临的任务是确定儿童的受伤是意外原因造成的,还是应该怀疑虐待行为。由于家庭跌倒是照顾者为了掩盖虐待创伤而提供的常见虚假病史,关于短距离跌倒的骨折可能性以及具体类型的信息 骨折可能是由不同的跌倒情况造成的,这可能有助于临床医生区分虐待和意外伤害,从而提高儿童虐待诊断的准确性。这项研究的目的是提供客观的、基于生物力学的关于短距离跌倒时股骨骨折潜能的信息。为了达到这一目标,已经确定了三个具体目标:(1)描述与幼儿短距离跌倒相关的股骨负荷(类型和幅度),(2)描述短距离跌倒时股骨骨折的可能性,(3)更好地理解儿童特有的骨骼特征对骨折潜力的影响。这项研究将涉及三个主要的方法学组成部分。首先,Crabi 12个月大的拟人测试装置(ATD)将进行改装,以提高腿部的生物保真度,并用于测量股骨负荷。然后,将使用改进的代理进行跌倒模拟,以确定股骨的载荷特性。最后一个组成部分涉及开发一个12个月大的人类儿童股骨的有限元模型。ATD实验的股骨载荷将在有限元模型中重现。这将提供对通过实验测量的组合加载方案的断裂潜力的洞察。此外,作为敏感性分析的一部分,模型中的关键参数将发生变化,以确定它们对裂缝潜力的影响。这将阐明儿童特有的特征(如骨密度)对股骨骨折潜力的影响。这项研究的结果将提供对儿童短距离跌倒中股骨骨折可能性的更好的理解,并为未来的工作奠定基础,这些工作将改善对损伤和病史的临床评估。此外,尽管这项研究的重点是股骨骨折潜力,但所使用的方法可能会作为未来研究其他骨骼骨折潜力的模型。

项目成果

期刊论文数量(2)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Femur loading in feet-first fall experiments using an anthropomorphic test device.
使用拟人测试装置进行脚先跌落实验中的股骨负载。
  • DOI:
    10.1016/j.jflm.2018.03.017
  • 发表时间:
    2018
  • 期刊:
  • 影响因子:
    1.5
  • 作者:
    Thompson,Angela;Bertocci,Gina;Smalley,Craig
  • 通讯作者:
    Smalley,Craig
Investigation of femur fracture potential in common pediatric falls using finite element analysis.
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GINA E. BERTOCCI其他文献

GINA E. BERTOCCI的其他文献

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{{ truncateString('GINA E. BERTOCCI', 18)}}的其他基金

An injury plausibility assessment model for differentiating abusive from accidental fractures in young children
区分幼儿虐待和意外骨折的伤害合理性评估模型
  • 批准号:
    10033417
  • 财政年份:
    2020
  • 资助金额:
    $ 7.47万
  • 项目类别:
An injury plausibility assessment model for differentiating abusive from accidental fractures in young children
区分幼儿虐待和意外骨折的伤害合理性评估模型
  • 批准号:
    10440510
  • 财政年份:
    2020
  • 资助金额:
    $ 7.47万
  • 项目类别:
An injury plausibility assessment model for differentiating abusive from accidental fractures in young children
区分幼儿虐待和意外骨折的伤害合理性评估模型
  • 批准号:
    10254257
  • 财政年份:
    2020
  • 资助金额:
    $ 7.47万
  • 项目类别:
An injury plausibility assessment model for differentiating abusive from accidental fractures in young children
区分幼儿虐待和意外骨折的伤害合理性评估模型
  • 批准号:
    10653078
  • 财政年份:
    2020
  • 资助金额:
    $ 7.47万
  • 项目类别:
Biomechanical Assessment of Femur Fracture in Pediatric Falls
儿童跌倒股骨骨折的生物力学评估
  • 批准号:
    8618419
  • 财政年份:
    2014
  • 资助金额:
    $ 7.47万
  • 项目类别:
Biomechanical Investigation of Pediatric Accidents
儿科事故的生物力学调查
  • 批准号:
    6623840
  • 财政年份:
    2002
  • 资助金额:
    $ 7.47万
  • 项目类别:
Biomechanical Investigation of Pediatric Accidents
儿科事故的生物力学调查
  • 批准号:
    6470409
  • 财政年份:
    2002
  • 资助金额:
    $ 7.47万
  • 项目类别:
Muscle fatigue in arthritis total hip replacement
关节炎全髋关节置换术中的肌肉疲劳
  • 批准号:
    6356335
  • 财政年份:
    1997
  • 资助金额:
    $ 7.47万
  • 项目类别:

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