The Toxicology Forum 40th Annual Summer Meeting

毒理学论坛第 40 届夏季年会

• 批准号: 8839077
• 负责人: JAMES E KLAUNIG
• 金额: $ 1.5万
• 依托单位: TOXICOLOGY FORUM
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-05 至 2015-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8839077
• 关键词: Toxicology; Forum; 40th; Annual; Summer

Project Summary Abstract The Toxicology Forum provides a unique venue for advancing US FDA's regulatory science agenda and thereby improving public health. The Toxicology Forum conducts transparent dialogues among various segments of society concerned with problems in toxicology. Each scientific session represents a carefully balanced approach to the designated topic with all sides of an issue presented for each topic. The unique, non- adversarial atmosphere of Toxicology Forum meetings results in frank and open discussions that do not need to arrive at consensus but foster a common understanding of the issue. Each scientific session of the Toxicology Forum provides an opportunity to develop a common understanding of the latest scientific data, the interpretation of the data and the policy implications of the findings. Programs in the past 15 years have emphasized new scientific tools (genomics, proteomics, metabolomics) and how these tools allow better decisions on safety of products regulated by the US FDA. There has been increased emphasis on challenging the traditional bioassays in terms of human relevance and discussion of alternative assays for product safety assessments have been the subject of multiple discussions which has help to develop a common understanding of the proper interpretation of this and other preclinical toxicology studies. These programs support the goals outlined in US FDA's Strategic plan for Regulatory Science and the advancement of public health. US FDA relevant elements of the Toxicology Forum that have been expanded and formalized in recent years include increasing opportunities for leading younger academic scientists to participate in Forum discussions through Travel Fellowships for young academic faculty. Another important change began in the late 1990s with the establishment of annual European meetings in Brussels, the seat of the European Union. This international scope supports US FDA's globalization efforts to strengthen national regulatory systems. While the specific issues and regulatory mechanisms may vary depending on the continent and country involved, the Toxicology Forum meetings continues to be a valid and productive way to explore and discuss issues with government, industry, academia, and consumer groups.

项目概要 摘要 毒理学论坛为推进美国 FDA 的监管科学议程和 从而改善公共卫生。毒理学论坛在不同领域之间进行透明对话 关心毒理学问题的社会阶层。每一次科学会议都代表着一次精心的 对指定主题采取平衡的方法，针对每个主题提出问题的各个方面。独特的、非 毒理学论坛会议的敌对气氛导致坦率和公开的讨论，而无需 达成共识，但促进对问题的共同理解。每届科学会议 毒理学论坛提供了一个对最新科学数据达成共识的机会， 数据解释以及研究结果的政策影响。 过去 15 年的计划强调新的科学工具（基因组学、蛋白质组学、代谢组学） 以及这些工具如何更好地对美国 FDA 监管的产品的安全性做出决策。已经有 更加强调在人类相关性和讨论方面挑战传统生物测定法 产品安全评估的替代分析方法已成为多次讨论的主题 有助于就该毒理学和其他临床前毒理学的正确解释达成共识 研究。这些计划支持美国 FDA 监管科学战略计划和 公共卫生的进步。 近年来美国 FDA 毒理学论坛的相关内容已得到扩展和正式化 包括增加年轻学术科学家参与论坛讨论的机会 通过为年轻学术教师提供旅行奖学金。另一个重要的变化始于 20 世纪 90 年代末 在欧盟所在地布鲁塞尔设立年度欧洲会议。这个国际 范围支持美国 FDA 加强国家监管体系的全球化努力。虽然具体 问题和监管机制可能因所涉及的大陆和国家而异，毒理学 论坛会议仍然是与政府探讨和讨论问题的有效且富有成效的方式， 工业界、学术界和消费者团体。