2014/2015 Enzymes, Coenzymes and Metabolic Pathways Gordon Research Conferences

2014/2015 酶、辅酶和代谢途径戈登研究会议

• 批准号: 8783440
• 负责人: Giovanni Gadda
• 金额: $ 0.6万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-06-15 至 2015-10-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8783440
• 关键词: Anti-Bacterial Agents; Antibiotic Resistance; Antineoplastic Agents; Area; Biochemical Reaction; Biological Process; Biology; Cancer Biology; Chemicals; Collaborations; Communication; Communities; Development; Enzymatic Biochemistry; Enzymes; Enzymes and Coenzymes; Fostering; Functional disorder; Future; Goals; Health; Human; Knowledge; Life; Link; Location; Malignant Neoplasms; Medical; Metabolic Pathway; Molecular; Molecular Biology; Outcome; Peripheral; Pharmaceutical Preparations; Process; Recording of previous events; Research; Research Personnel; Resort; Role; Running; Scientist; Senior Scientist; Thinking; Vision; Work; abstracting; base; biophysical chemistry; catalyst; chemical reaction; enzyme mechanism; human disease; improved; meetings; metabolic abnormality assessment; novel therapeutics; peer; posters; programs; public health relevance; success; symposium; tumor progression

DESCRIPTION (provided by applicant): With this proposal we seek partial support for the 2014 and 2015 "Enzymes, Coenzymes, and Metabolic Pathways" Gordon Research Conference. These conferences will occur from July 13 - 18, 2014 and in July 2015 at the Waterville Valley Resort, in Waterville Valley, NH. The 'Enzymes' GRC is the pivotal conference for researchers focused on investigating the molecular mechanisms of biochemical reactions, and provides a central meeting place for the exchange of ideas. The long-term goals of this conference are to foster interactions and communication within the research community focused on studying the roles of enzymes in the biological processes that are fundamental for life. To achieve these goals, we will assemble a program of ~36 speakers that comprise 28 invited talks and 8 chosen from poster abstracts. These talks will describe current advances in enzyme mechanisms, chemical biology, cancer biology and antibiotic resistance, as well as how these areas link to both normal and pathological life processes. During the afternoon, poster sessions will be held where all attendees can present their work to the broader community of scientists. These poster sessions provide a unique opportunity for junior scientists and senior investigators to interact. This proposal is highly significant because the Enzymes, Co-Enzymes and Metabolic Pathways GRC is the pivotal conference for researchers focused on investigating the molecular mechanisms of biochemical reactions, and provides a central meeting place for the exchange of ideas. Furthermore, this meeting continues to showcase the very best in enzyme and metabolic studies as well as their relevance to human diseases. From a medical perspective, this proposal is highly significant due to the focus areas of cancer and anti-bacterials. A key outcome of this proposal will be to further advance our understanding of how enzymes, co-enzymes and metabolic pathways contribute to the onset and progression of cancer, to the development of antibiotic resistance, and how these can be targeted by the development of novel therapeutics.

描述（由申请人提供）：通过此提案，我们寻求2014年和2015年“酶，辅酶和代谢途径”戈登研究会议的部分支持。这些会议将于2014年7月13日至18日和2015年7月在新罕布什尔州沃特维尔山谷的沃特维尔山谷度假村举行。“酶”GRC是研究人员专注于研究生化反应的分子机制的关键会议，并为思想交流提供了一个中心会议场所。本次会议的长期目标是促进研究界的互动和交流，重点是研究酶在生命的基本生物过程中的作用。为了实现这些目标，我们将组织一个约36名演讲者的计划，其中包括28个受邀演讲和8个从海报摘要中选出的演讲者。这些讲座将描述酶机制，化学生物学，癌症生物学和抗生素耐药性的最新进展，以及这些领域如何与正常和病理生命过程联系起来。下午，将举行海报会议，所有与会者都可以向更广泛的科学家社区展示他们的工作。这些海报会议为初级科学家和高级研究人员提供了一个独特的互动机会。这一提议非常重要，因为酶，辅酶和代谢途径GRC是研究人员专注于研究生化反应分子机制的关键会议，并为思想交流提供了一个中心会议场所。此外，本次会议将继续展示酶和代谢研究的最佳成果及其与人类疾病的相关性。从医学角度来看，由于癌症和抗菌药物的重点领域，该提案具有非常重要的意义。该提案的一个关键成果将是进一步推进我们对酶、辅酶和代谢途径如何促进癌症的发生和进展、抗生素耐药性的发展以及如何通过开发新疗法来靶向这些方面的理解。