Investigation of the functional role of antibodies against myelin proteolipid protein in multiple sclerosis

髓磷脂蛋白脂质蛋白抗体在多发性硬化症中的功能作用研究

• 批准号: nhmrc : 1063170
• 负责人: A/Pr Judith Greer
• 金额: $ 41.75万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/investigation-functional-role-multiple-sclerosis/455045
• 关键词: Investigation; functional; role; antibodies; against

There is a lot of suggestive evidence that molecules called antibodies might cause a faster progression of disease in people with multiple sclerosis (MS), but this remains to be proven. The proposed study will investigate the mechanisms by which antibodies could hasten MS disease progression. Results of this study will help inform treatment options for people with MS and will also help us to better understand the basic pathogenic mechanisms that can cause MS.

有很多暗示性的证据表明，一种叫做抗体的分子可能会导致多发性硬化症（MS）患者的疾病进展更快，但这还有待证实。这项拟议的研究将探讨抗体加速多发性硬化症进展的机制。这项研究的结果将有助于为多发性硬化症患者提供治疗方案，也将帮助我们更好地了解可能导致多发性硬化症的基本致病机制。