Understanding how a parasite-derived peptide prevents immune mediated demyelination

了解寄生虫衍生肽如何预防免疫介导的脱髓鞘

• 批准号: nhmrc : 1142006
• 负责人: A/Pr Judith Greer
• 金额: $ 33.6万
• 依托单位: University of Technology Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/understanding-parasite-derived-mediated-demyelination/1319614
• 关键词: Understanding; how; parasite; derived; peptide

Over millennia of co-evolution with humans, parasitic worms have developed the capacity to modulate the human immune system. We have characterised and identified novel molecules secreted by these worms. In this project we will assess the therapeutic potential of the parasite molecules using animal models of relapsing remitting multiple sclerosis.

在与人类共同进化的数千年中，寄生蠕虫已经发展出调节人类免疫系统的能力。我们已经表征并鉴定了这些蠕虫分泌的新分子。在这个项目中，我们将使用复发缓解型多发性硬化症的动物模型来评估寄生虫分子的治疗潜力。