Mentoring and Research in Patient-Oriented Integrative Medicine

摘要 K24职业中期研究员奖为王晨晨博士提供了一个令人兴奋的合作机会 与塔夫茨、布朗、哈佛和波士顿大学医学院的知名科学家一起指导新的 希望为补充和替代医学中以患者为中心的研究做出贡献的研究人员 (凸轮)。目前，王博士是塔夫茨大学医学院副教授兼 塔夫茨补充和综合医学中心，拥有良好的研究、出版和 辅导。她是美国国立卫生研究院资助的两个研究比较有效性的R01项目的首席研究员 以及骨性关节炎和纤维肌痛以及创伤后心身干预的成本效益 军人人群中的应激障碍 王博士的长期目标是推进心身医学的科学，以促进健康和康复。 她的当前目标是获得受保护的时间，以培训下一代CAM科学家在患者- 以研究为导向，扩大其创新性、多方法、多学科的临床和翻译 针对慢性致残情况的研究计划。王博士已经建立了有效的记录 指导不同背景的各级学员，包括来自不同国家和地区的临床医生和 纪律。她的CAM指导计划，以及她在身心干预方面的专业知识，已经完全 整合到塔夫茨临床和转化科学研究所的研究和教学基础设施中。 结合突出的资源和长期公认的多样化培训环境，这些被选中的 学员将接受严格的科学方法论、诚信、道德和拨款申请方面的培训。 有必要通过多学科团队促进高质量、翻译性的、以患者为导向的研究。 在NCCAM资助的R21和R01研究的基础上，拟议的研究旨在：1)评估比较 心身干预的有效性和成本效益；2)阐明心身干预的神经生物学机制 CAM疗法；3)调查新的、成本效益高的CAM疗法未得到满足的需求；4)创造 在CAM培训中采用跨学科的综合方法；5)发展科学性和结构性 为未来的R01和其他计划应用奠定基础；6)向新科学家提供机会，以 将CAM融入主流机构和研究环境。因此，这款K24将促进 面向下一代研究人员的多学科以患者为导向的研究，以便实质性地 促进综合医学的科学研究以及对健康、保健和全民福祉的贡献。

ABSTRACT The K24 Midcareer Investigator Award presents Dr. Chenchen Wang with an exciting opportunity to collaborate with renowned scientists at Tufts, Brown, Harvard, and Boston University Schools of Medicine to mentor new investigators who wish to contribute to patient-oriented research in Complementary and Alternative Medicine (CAM). Currently Dr. Wang is Associate Professor at Tufts University School of Medicine and Director of the Tufts Center for Complementary and Integrative Medicine, with a strong record of research, publication, and mentoring. She is the Principal Investigator of two NIH-funded R01 projects studying comparative-effectiveness and cost-effectiveness of mind-body interventions for osteoarthritis and fibromyalgia, as well as post-traumatic stress disorder in military populations Dr. Wang's long-term goal is to advance the science of mind-body medicine to promote health and healing. Her immediate goals are to obtain protected time to train the next generation of CAM scientists in patient- oriented research and to expand her innovative, multi-method, multidisciplinary clinical and translational research programs for chronic disabling conditions. Dr. Wang has an established track record of effectively mentoring trainees at various levels with diverse backgrounds, including clinicians from different countries and disciplines. Her CAM mentoring program, as well as her expertise on mind-body interventions, has been fully integrated into the research and teaching infrastructure of the Tufts Clinical and Translational Science Institute. Combined with outstanding resources and a long-recognized diverse training environment, these selected mentees will obtain training in rigorous scientific methodology, integrity, ethics, and grant applications necessary to stimulate high-quality, translational, patient-oriented research with a multidisciplinary team. Building upon NCCAM-funded R21 and R01 studies, the proposed research aims to:1) Evaluate comparative effectiveness and cost-effectiveness of mind-body interventions; 2) Elucidate neurobiological mechanisms of CAM therapies; 3) Investigate unmet needs of novel and cost-effective CAM treatments; 4) Create comprehensive interdisciplinary approaches in CAM training; 5) Develop the scientific and structural foundations for future R01 and other program applications; 6) Extend opportunities to new scientists to integrate CAM into mainstream institutions and research settings. This K24 will therefore promote multidisciplinary patient-oriented research for the next generation of investigators in order to substantially advance the science on integrative medicine and the contributions to health, health care, and well-being for all.