Cincinnati Regional Coordinating Stroke Center (Cincinnati RCC)

描述(由申请人提供)：建议的NINDS卒中临床试验网络(NSTN)的目标是利用多学科的卒中专业知识，在所有阶段协作和高效地设计和执行卒中临床试验。我们将作为NSTN的区域协调中心(RCC)，为中风带来一个全面整合的临床试验网络方法，范围更广，更具凝聚力。我们的目标是(1)有效地实施试验，招募和留住参与者，并作为RCC优化数据质量，(2)作为经验丰富的科学家、临床医生、试验者和协调员积极参与NSTN，以及(3)成功培训 下一代中风临床试验者。我们将通过带来经验丰富的领导、接触到多样化的患者群体、成熟的研究基础设施和支持性的管理来实现这些目标。我们的机构已经表明了他们对NSTN的承诺，同意使用标准化的主试验协议，采用集中的IRB审查，并提供额外的机构资金来支持RCC学员。我们计划成为NSTN的关键合作伙伴，致力于通过高质量的中风试验为我们的患者带来最具临床效果的中风疗法。

DESCRIPTION (provided by applicant): The objectives of the proposed NINDS Stroke Clinical Trials Network (NSTN) are to harness multidisciplinary stroke expertise to collaboratively and efficiently design and execute stroke clinical trials in all phases. We will bring a fully integratd clinical trial network approach to stroke more broadly and cohesively as a Regional Coordinating Center (RCC) of the NSTN. Our goals are to (1) efficiently implement trials, recruit and retain participants, and optimize data quality as an RCC, (2) actively participate in the NSTN as experienced scientists, clinicians, trialists, and coordinators, and (3) successfully train the next generation of stroke clinical trialists. We will achieve these goals by bringing experienced leadership, access to a diverse patient population, an established research infrastructure, and a supportive administration. Our institution has shown their commitment to the NSTN by agreeing to use a standardized Master Trial Agreement, employ a centralized IRB review, and provide additional institutional funds to support the RCC trainee. We propose to be a key partner in the NSTN working to bring the most clinically impactful stroke therapies to our patients through high-quality stroke trials.