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Preventing excessive gestational weight gain in obese women

预防肥胖女性妊娠期体重过度增加

基本信息

批准号：
8890180
负责人：
Suzanne Phelan
金额：
$ 62.93万
依托单位：
CALIFORNIA POLY STATE U SAN LUIS OBISPO
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
起止时间：
2011-09-23 至 2018-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8890180
关键词：
Adherence Affect Age-Months Apgar Score Behavior Behavior Therapy Behavioral Birth trauma Blood Pressure Body Image Calories Constipation Cromolyn Sodium Diet Disinhibition Eating Environment Equilibrium Ethnic Origin Exercise Fasting Fatty acid glycerol esters Feedback Food Frequencies Gestational Diabetes Glucose Goals Health Hispanics Home environment Incidence Infant Institute of Medicine (U.S.)Instruction Insulin Intake Intervention Length Life Style Lipids Liquid substance Low Birth Weight Infant Measures Modeling Moods Mothers Not Hispanic or Latino Nutritional Obesity Overweight Participant Physical activity Physiological Population Postpartum Period Pre-Eclampsia Pregnancy Prevention Procedures Publishing Randomized Randomized Controlled Trials Recommendation Recruitment Activity Relative (related person)Research Research Project Grants Site Testing Time Very Light Exercise Weight Weight Gain Weight maintenance regimen Woman Work base fast food gestational weight gain good diet healthy weight improved innovation lifestyle intervention meetings nutrition offspring prevent programs psychosocial randomized trial restraint sedentary sound standard care sugar sweetened beverage

项目摘要

Low-intensity lifestyle interventions during pregnancy can prevent excessive gestational weight gain in normal weight women. However, preventing excessive gestational weight gain in obese women has proven more difficult. Intensive interventions involving prescription of specific calorie goals and balanced nutrition have shown the most promise, but, similar to non-pregnant populations, promoting ongoing adherence to caloric prescription remains a significant challenge. Liquid meal-replacement products have been shown to promote adherence to calorie and weight goals in non-pregnant multiethnic populations. Moreover, they have been used during pregnancy as a supplement to improve nutritional adequacy and shown to be safe and to result in improved dietary intal<e. However, no study to date has evaluated this approach as a means to prevent excessive weight gain during pregnancy. The principal aim of this study is to determine whether a multi-component lifestyle intervention that incorporates partial meal replacements during pregnancy can reduce the number of obese women who exceed the lOM recommendations for weight gain during pregnancy. In this two-site randomized trial, 430 obese women, 50% Hispanic, will be randomized within site and ethnicity into either a multi-component lifestyle modification treatment with partial meal replacement program (N=215) or standard care (N=215). Treatment will occur during pregnancy, using standardized intervention procedures from our previous work. All women will be recruited and assessed early in pregnancy (between 10 and 16 weelis), at 30 weeks gestation, and at 6 months, and 12 months postpartum with anthropometric measures obtained at delivery and at 2 months postpartum. We believe this project is significant because it deals with the prevention of excessive gestational weight gain and its associated adverse maternal and offspring health consequences. The study is also innovative; there have been no randomized controlled trials evaluating the effects of a behavioral lifestyle intervention with partial meal replacement program to promote healthy weight gain in multiethnic obese women.

怀孕期间低强度的生活方式干预可以防止妊娠期体重过度增加