Pilot/Exploratory Studies Core

试点/探索性研究核心

• 批准号: 8877176
• 负责人: Taylor Sohn Riall
• 金额: $ 3.24万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8877176
• 关键词: Abbreviations; Acute; Address; Aging; American; Applications Grants; Area; Award; Biology; Biometry; Budgets; Capsicum; Caring; Clinical Research; Clinical Sciences; Clinical Trials; Collaborations; Elderly; Enrollment; Ensure; Faculty; Funding; Geriatrics; Goals; Grant; Institute of Medicine (U.S.); Institutes; Institutional Review Boards; Interdisciplinary Study; Intervention; Leadership; Medical; Mentorship; Metabolism; Methodology; Minority Groups; Mission; Monitor; Outcome; Outcomes Research; Pathway interactions; Patient-Focused Outcomes; Physical Function; Physical activity; Pilot Projects; Principal Investigator; Process; Recovery; Recovery of Function; Recruitment Activity; Research; Research Personnel; Research Project Grants; Research Proposals; Research Support; Resources; Safety; Schools; Science; Source; Staging; Texas; Training; Translational Research; Underrepresented Minority; United States National Aeronautics and Space Administration; Universities; Women' s Health; Work; abstracting; career development; data management; design; functional gain; functional loss; human subject protection; improved; innovation; interest; multidisciplinary; new technology; novel strategies; nutrition; research facility; sarcopenia

Pilot/Exploratory Studies Core Summary/Abstract The Pilot/Exploratory Studies Core (PESC) is the main engine of scientific innovation for the OAIC. The goal of the Core is to stimulate new research relevant to the OAIC theme, which is to Identify pathways of physical function loss and gain and develop targeted interventions to improve functional recovery from illness in older adults. Activities of the PESC will contribute to the overall goals of the OAIC by identifying and supporting innovative translational research projects focused on understanding the pathways of functional loss, and improving physical function and recovery in older adults. We will employ our assets and partner with other institutional resources to accomplish the following specific aims: 1. Solicit and select the most meritorious research proposals for PESC funding. 2. Identify opportunities for co-sponsorship of PESC studies. 3. Provide PESC investigators with access to resources from other OAIC cores and institutional research facilities/centers. 4. Monitor the progress of PESC studies. 5. Ensure regulatory compliance, safety and protection of human subjects enrolled in PESC studies. 6. Provide assistance and mentorship to develop PESC studies into independently funded grant applications. We target early stage investigators, including Scholars not directly funded through the RCDC, and also investigators well established in other areas who can turn their expertise to develop parallel studies in aging consistent with the OAIC theme. The PESC funds one or two-year pilot grants and small exploratory projects. The PESC mobilizes our substantial institutional resources to support research efforts from the bench to clinical trials and patient-centered outcomes research in geriatrics. We have selected four pilot/exploratory studies for the first year of the new cycle. The PESC process is broader than simply awarding funds for OAIC pilot research. The goal is to support aging research at the institutional level. The most important outcome is new external funding resulting from work supported by the PESC.

初步/探索性研究核心摘要/摘要 试点/探索性研究核心（PESC）是OAIC科学创新的主要引擎。的目标 核心是激励与OAIC主题相关的新研究，即确定物理途径 功能丧失和获得，并制定有针对性的干预措施，以改善老年人疾病后的功能恢复 成年人了PESC的活动将通过确定和支持OAIC的总体目标 创新的转化研究项目侧重于了解功能丧失的途径， 改善老年人的身体功能和恢复。我们将利用我们的资产，与其他 机构资源，以实现以下具体目标： 1.征集和选择最有价值的研究计划，以获得PESC的资助。 2.确定共同赞助PESC研究的机会。 3.为PESC研究人员提供从其他OAIC核心和机构研究获得资源的机会 设施/中心。 4.监测PESC研究的进展。 5.确保入组PESC研究的人类受试者的监管合规性、安全性和保护。 6.提供援助和指导，以发展PESC研究到独立资助的赠款申请。 我们的目标是早期阶段的研究人员，包括不直接通过RCDC资助的学者， 研究人员在其他领域建立了良好的基础，可以将他们的专业知识用于开展老龄化方面的平行研究 符合OAIC的主题。PESC为一年或两年的试点赠款和小型探索性项目提供资金。 PESC动员我们大量的机构资源来支持从板凳上的研究工作， 临床试验和以患者为中心的老年医学结果研究。我们选择了四个试点/探索性的 新周期第一年的研究。PESC的过程比简单地为OAIC提供资金更广泛 试点研究。目标是支持机构一级的老龄化研究。最重要的结果是 由PESC支持的工作产生的新的外部资金。