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中文摘要
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 描述(由申请人提供):匹兹堡大学玛吉妇女研究所妇女生殖健康研究(WRHR)职业发展计划的具体目标是为生殖生物学和医学领域富有成效和令人兴奋的研究生涯培养产科和妇科领域的优秀初级教员。这一具体目标与匹兹堡大学产科、妇科和生殖科学系Magee妇女研究所的核心使命一致,即培训杰出的个人,追求生殖科学知识,并将基本发现转化为改善妇女及其婴儿的健康。我们的计划将每年支持两名学者参加基于实验室的基础或转化性培训的结构良好的课程。这些学者将在博士后奖学金的最后研究年度从OBGYN驻院实习的毕业生或OBGYN分专业研究员中挑选。我们有能力有选择地针对基础生殖生物学或翻译生殖生物学的受训人员,这得到了麦吉妇女研究所丰富而全面的基础研究计划的支持。该研究所包括一座最近翻新的12.5万平方英尺的实验室研究大楼,配备了最先进的技术和设备,这些设备存放在单独的实验室或综合核心设施中。在一个由50多名生殖生物学研究人员组成的社区中,我们选择了一组18名杰出的导师,他们将在整个培训过程中指导WRHR学者。这些导师是根据他们之前指导成功人士的丰富历史、创造性的科学项目、生产力、完善的实验室以及对研究教育和指导的强烈奉献而被挑选出来的。此外,所有代表生殖生物学研究的多样化和丰富组合的导师,都有被证明有能力获得外部资金。一个由外部审查委员会监督的内部咨询委员会将监督和监督该计划的质量和个别学者按照明确界定的里程碑取得的进展。一个基于一套复杂工具的综合评估系统将向PI、研究总监和咨询委员会提供反馈,使该计划保持卓越。MAGEE妇女WRHR计划将培训基础和转化生殖医学方面的未来领导者。我们以前的记录和目前的资源在妇产科中是无与伦比的,是培养初级医生科学家的职业生涯进入研究独立性的理想选择,从而丰富生殖医学,拥有合格的个人,将带领我们的专业进入令人兴奋的未来。
英文摘要
 DESCRIPTION (provided by applicant): The specific aim of the Women's Reproductive Health Research (WRHR) Career Development Program at Magee-Women's Research Institute, the University of Pittsburgh, is to prepare outstanding junior faculty in the field of obstetrics and gynecology for a productive and exciting investigative career in reproductive biology and medicine. This specific aim aligns with the core mission of Magee Women's Research Institute of the Department of Obstetrics, Gynecology and Reproductive Sciences at the University of Pittsburgh to train exceptional individuals, pursue knowledge in reproductive sciences and to translate basic discoveries into improved health for women and their babies. Our program will support two scholars per year in a well-structured curriculum of basic or translational laboratory-based training. The scholars will be selected among either graduates of an OBGYN residency or among OBGYN sub-specialty fellows in the final research year of postdoctoral fellowship. Our ability to selectively target trainees in basic or translational reproductive biology is supported y the rich and comprehensive fundamental research programs at Magee-Women's Research Institute. The institute includes a recently renovated laboratory research building of 125,000 square feet, furnished with state-of-the-art technology and equipment items that are housed in individual laboratories or integrated core facilities. Among a community of more than 50 reproductive biology researchers we selected a group of 18 exceptional mentors who will guide the WRHR scholars throughout their training. The mentors were selected based on their previous rich history of mentoring successful individuals, creative scientific programs, productivity, well-established laboratories, and a strong dedication to research education and mentorship. Furthermore, all mentors, who represent a diverse and rich portfolio of reproductive biology research, have a proven ability to secure extramural funding. An Internal Advisory Committee, monitored by an External Review Board, will oversee and monitor the program's quality and the progress of individual scholars along well-defined milestones. A comprehensive evaluation system, which is based on a set of sophisticated tools, will provide feedback to the PI, Research Director, and Advisory Committee, allowing the program to maintain excellence. Magee-Women's WRHR program will train the future leaders in basic and translational reproductive medicine. Our previous record and current resources that are unrivaled among departments of obstetrics and gynecology are ideal to nurture careers of junior physician scientists into research independence, and thereby enrich reproductive medicine with well-qualified individuals that will lead our specialty into the exciting future.
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Project 1: EZH2 Inhibition to Prevent/Overcome Chemoresistance
Project 2: Local immunotherapy corrects chemokine patterns in ovarian cancer
  • 批准号:
    10362701
  • 项目类别:
  • 资助金额:
    $57.68万
  • 财政年份:
    2020
  • 负责人:
    Robert Page Edwards
  • 依托单位:
Ovarian Cancer: Prevention of the Disease and Its Recurrence
海外基金