Eunice Kennedy Shriver NICHD Cooperative Multicenter Neonatal Research Network

尤尼斯·肯尼迪·施赖弗 (Eunice Kennedy Shriver) NICHD 合作多中心新生儿研究网络

• 批准号: 8826784
• 负责人: Gregory M. Sokol
• 金额: $ 30.34万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8826784
• 关键词: Academic Medical Centers; Address; Admission activity; Area; Basic Science; Biological Markers; Birth; Bronchopulmonary Dysplasia; Caring; Cellular biology; Child; Child health care; Childhood; Clinical; Clinical Management; Clinical Research; Clinical Services; Clinical Trials; Clinical Trials Design; Clinical and Translational Science Awards; Collaborations; Conduct Clinical Trials; Critical Illness; Databases; Development; Dietary Intervention; Discipline of obstetrics; Disease; Educational process of instructing; Enrollment; Equilibrium; Evaluation Research; Faculty; Foundations; Funding; Generic Drugs; Genomics; Growth and Development function; Gynecology; Health; Hematopoiesis; Hospitals; Human Development; Indiana; Individual; Infant; Institutes; Instruction; Life; Link; Low Birth Weight Infant; Maternal and Child Health; Medical; Medical center; Medicine; Mission; Molecular Immunology; Multicenter Neonatal Research Network; National Institute of Child Health and Human Development; Neonatal; Newborn Infant; Observational Study; Only Child; Outcome; Patients; Pediatric Hospitals; Pediatric Research; Perinatal; Pharmacogenetics; Play; Population; Premature Infant; Proteomics; Protocols documentation; Randomized Clinical Trials; Recording of previous events; Research; Research Activity; Research Design; Research Infrastructure; Research Personnel; Research Support; Resources; Role; Services; Site; Staging; Stem cells; Therapeutic Human Experimentation; Translational Research; United States National Institutes of Health; Universities; Visit; angiogenesis; design; developmental nutrition; experience; fetal; follow-up; high risk; improved; indexing; innovation; medical schools; member; neonatal care; neonate; nutrition; patient population; premature; programs; research facility; sildenafil; stem cell biology

DESCRIPTION (provided by applicant): The Eunice Kennedy S/7nVer National Institute of Child Health and Human Development Neonatal Research Network is a cooperative group of academic centers that perform multicenter clinical trials to investigate problems in neonatal medicine, particularly those related to low birth weight, prematurity, and common neonatal medical problems. The Indiana University School of Medicine is the only medical school and the site of the only comprehensive children's hospital in Indiana, a state with a population of 6.4 million and 88,000 annual births. Located at the geographical center of the state in Indianapolis, the Indiana University Medical Center serves as the principal referral center for high-risk perinatal patients and critically ill neonates. The clinical, teaching and research programs of the Section of Neonatal-Perinatal Medicine have a long tradition of excellence. Specific areas of expertise include clinical trials, fetal and neonatal nutrition, developmental hematopoiesis, molecular immunology, and stem cell biology. Since 1991, Indiana University has had continuous funding and has made significant contributions to the Neonatal Research Network because of the large patient population available for studies, state-of-the-art clinical and research facilities and clinical research infrastructure, strong investigators with extensive clinical research expertise, and excellent research support staff. During the next funding cycle, Indiana University will continue to contribute a large number of subjects to all observational studies and clinical trials conducted by the Neonatal Research Network and will contribute to the scientific mission through development of innovative research protocols designed to address important clinical questions.

描述（由申请人提供）：Eunice Kennedy S/7 nVer国家儿童健康和人类发展研究所新生儿研究网络是一个学术中心合作小组，进行多中心临床试验，调查新生儿医学问题，特别是与低出生体重，早产和常见新生儿医学问题有关的问题。医学的印第安纳州大学是唯一的医学院和唯一的综合性儿童医院的网站在印第安纳州，一个国家的人口640万和88,000年出生。印第安纳州大学医学中心位于印第安纳波利斯州的地理中心，是高危围产期患者和危重新生儿的主要转诊中心。新生儿-围产医学科的临床、教学和科研项目具有悠久的优良传统。具体的专业领域包括临床试验，胎儿和新生儿营养，发育造血，分子免疫学和干细胞生物学。自1991年以来，印第安纳州大学一直有持续的资金，并作出了重大贡献的新生儿研究网络，因为大量的患者人群可用于研究，国家的最先进的临床和研究设施和临床研究基础设施，强大的研究人员具有广泛的临床研究专业知识，和优秀的研究支持人员。在下一个资助周期，印第安纳州大学将继续贡献大量的科目，所有的观察性研究和新生儿研究网络进行的临床试验，并将有助于通过创新的研究方案，旨在解决重要的临床问题的发展的科学使命。

项目成果

Changes in arterial oxygen tension when weaning neonates from inhaled nitric oxide.

新生儿断奶时吸入一氧化氮时动脉氧张力的变化。

• DOI: 10.1002/ppul.1083
• 发表时间: 2001
• 期刊: Pediatric pulmonology
• 影响因子: 3.1
• 作者: Sokol,GM;Fineberg,NS;Wright,LL;Ehrenkranz,RA
• 通讯作者: Ehrenkranz,RA

Nitrogen dioxide formation during inhaled nitric oxide therapy.

吸入一氧化氮治疗期间形成二氧化氮。

• 发表时间: 1999
• 期刊: Clinical chemistry
• 影响因子: 9.3
• 作者: Sokol,GM;VanMeurs,KP;Wright,LL;Rivera,O;Thorn3rd,WJ;Chu,PM;Sams,RL
• 通讯作者: Sams,RL