Miroscopy

科赫研究所研究项目的主要重点是了解分子和细胞的变化， 与癌症发展和进展相关，并开发新的治疗和诊断方法。 显微镜核心在细胞和体内环境中提供最先进的成像， 这些研究的重要工具。在本报告所述期间，这一核心的能力得到了扩大， 增强这包括：搬进新科赫研究所大楼内更大的定制设计空间; 新仪器的购置;以及招募了世界知名的活体成像专家Jeffrey 维科夫，致内核全体人员值得注意的是，在同一时期，78%的中心成员使用显微镜核心， 包括四个项目的调查员因此，这种共享资源对于成功的 科赫研究所的使命。在接下来的一段时间里，这一核心将继续提供广泛的最先进的 成像技术，以支持中心成员的研究计划。为了支持其扩大的工作人员， 第44年的请求预算比第44年的请求和建议预算增加45%。 39.其他科赫研究所核心的CCSG预算已经减少或取消，以抵消 增加了这个和其他的核心。

A primary focus of the Koch Institute’s research program is to understand the molecular and cellular changes associated with cancer development and progression and develop new treatments and diagnostic approaches. The Microscopy Core provides state-of-the-art imaging in both cells and in the in vivo setting, which are essential tools for these studies. In the current period, the capabilities of this Core have been expanded and enhanced. This includes: moving into a larger, custom-designed space in the new Koch Institute building; the acquisition of new instrumentation; and the recruitment of a world-renowned expert in intravital imaging, Jeffrey Wyckoff, to the Core’s staff. Notably, in the same period, 78% of Center Members used the Microscopy Core, including investigators from all four Programs. Thus, this Shared Resource is essential to the success of the Koch Institute mission. In the upcoming period, this Core will continue to offer a wide range of state-of-the-art imaging technologies to support the research programs of Center Members. To support its expanded staff, the requested budget for Year 44 is increased 45%, compared to the requested and recommended budget in Year 39. The CCSG budgets of other Koch Institute Cores have been reduced or eliminated to more than offset the proposed increase in this, and other, Cores.