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Structure and function of alpha-synuclein

Structure and function of alpha-synuclein
α-突触核蛋白的结构和功能
批准号：
8786187
负责人：
David Eliezer
金额：
$34.38万
依托单位：
WEILL MEDICAL COLL OF CORNELL UNIV
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
项目状态：
已结题
起止时间：
2015-04-01 至 2020-03-31
来源：
https://reporter.nih.gov/project-details/8786187
关键词：
AcetylationAdoptedAldicarbBindingBiological AssayCaenorhabditis elegansCalciumCell membraneComplementComplexComputer SimulationDataDetergentsDiseaseDockingEnvironmentGrantHandIn SituIn VitroLightLipidsMediatingMembraneMembrane ProteinsModelingMolecular ConformationMonitorMutationN-terminalOrganismPhosphorylationPhosphorylation SitePhosphotransferasesPlayProcessPropertyProteinsReagentRecombinantsReportingRoleS-nitro-N-acetylpenicillamineSNAP receptorSiteStructural ModelsStructureSynapsesSynaptic VesiclesTherapeuticUniversitiesVAMP-2VariantVesicleWorkabstractingalpha synucleinbasedesignin vitro activityin vivointerestlight effectsmedical schoolsmutantneurotransmitter releasenovelprotein functionprotein protein interactionscreeningsingle moleculesynaptosomal-associated protein 25synaptotagminsyntaxin 1synucleintherapeutic targetvalidation studiesvesicle-associated membrane protein

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