Exposure Assessment, Biomarkers and Metabolomics FC

接触评估是描述人类与环境（包括职业环境）接触和从环境中吸收物剂的过程。对于一种特定物剂，准确地量化接触对于旨在确定剂量-反应关系的流行病学研究和量化对接触个人或人群产生有害影响的可能性的风险评估研究至关重要。 如果危害风险被低估，对接触的错误分类可能导致无法充分保护公众健康。或者，如果由于暴露测量不准确而高估了特定物剂造成的健康风险，则不必要地浪费了稀缺的公共卫生资金。 EABM-FC的首要使命是为CEEH研究人员提供最先进的暴露评估工具，以可靠地量化环境中的暴露以及随后的健康后果，并了解基因-环境相互作用在调节健康结果中的作用。

Exposure assessment is the process of characterizing human contact with and uptake of agents from the environment (including the occupational environment). Given a particular agent, accurate quantification of exposure is critical for epidemiological studies that seek to define dose-response relationships and for risk assessment studies that quantify the probability of a harmful effect to exposed individuals or populations. Misclassification of exposure can lead to failure to adequately protect public health if the risk of harm is underestimated. Alternatively, if the health risk posed by a specific agent is overestimated due to inaccurate measures of exposure, scarce public health dollars are wasted needlessly. The overarching mission of EABM-FC is to provide state-of-the-art exposure assessment tools to CEEH investigators in order to reliably quantify exposure to agents in the environmental and subsequent health consequences and understand the role that gene-environment interactions play in modulating health outcomes.