Exposure Assessment, Biomarkers and Metabolomics FC
暴露评估、生物标志物和代谢组学 FC
基本信息
- 批准号:8650860
- 负责人:
- 金额:$ 13.63万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2014
- 资助国家:美国
- 起止时间:2014-04-01 至 2016-03-31
- 项目状态:已结题
- 来源:
- 关键词:BiologicalBiological AssayBiological MarkersChemical AgentsChemicalsCollectionConsultationsCore FacilityDataDiseaseDoseEnvironmentEnvironmental HealthEpidemiologic StudiesExposure toFailureGoalsHealthHealth SciencesHumanIndividualLeadMass Spectrum AnalysisMeasurementMeasuresMetalsMissionOccupationalOutcomeParticulatePlayPopulationProbabilityProcessPublic HealthResearch PersonnelRiskRisk AssessmentRoleSamplingServicesTissuesbasegene environment interactionmetabolomicsresponsetooluptakevolatile organic compoundwasting
项目摘要
Exposure assessment is the process of characterizing human contact with and uptake of agents from the environment (including the occupational environment). Given a particular agent, accurate quantification of exposure is critical for epidemiological studies that seek to define dose-response relationships and for risk assessment studies that quantify the probability of a harmful effect to exposed individuals or populations.
Misclassification of exposure can lead to failure to adequately protect public health if the risk of harm is underestimated. Alternatively, if the health risk posed by a specific agent is overestimated due to inaccurate measures of exposure, scarce public health dollars are wasted needlessly.
The overarching mission of EABM-FC is to provide state-of-the-art exposure assessment tools to CEEH investigators in order to reliably quantify exposure to agents in the environmental and subsequent health consequences and understand the role that gene-environment interactions play in modulating health outcomes.
接触评估是描述人类与环境(包括职业环境)接触和从环境中吸收物剂的过程。对于一种特定物剂,准确地量化接触对于旨在确定剂量-反应关系的流行病学研究和量化对接触个人或人群产生有害影响的可能性的风险评估研究至关重要。
如果危害风险被低估,对接触的错误分类可能导致无法充分保护公众健康。或者,如果由于暴露测量不准确而高估了特定物剂造成的健康风险,则不必要地浪费了稀缺的公共卫生资金。
EABM-FC的首要使命是为CEEH研究人员提供最先进的暴露评估工具,以可靠地量化环境中的暴露以及随后的健康后果,并了解基因-环境相互作用在调节健康结果中的作用。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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CHRISTOPHER D SIMPSON其他文献
CHRISTOPHER D SIMPSON的其他文献
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{{ truncateString('CHRISTOPHER D SIMPSON', 18)}}的其他基金
OCCUPATIONAL SAFETY AND HEALTH EDUCATION AND RESEARCH CENTERS (T42)
职业安全健康教育研究中心(T42)
- 批准号:
10255487 - 财政年份:2020
- 资助金额:
$ 13.63万 - 项目类别:
OCCUPATIONAL SAFETY AND HEALTH EDUCATION AND RESEARCH CENTERS (T42)
职业安全健康教育研究中心(T42)
- 批准号:
10674594 - 财政年份:2020
- 资助金额:
$ 13.63万 - 项目类别:
OCCUPATIONAL SAFETY AND HEALTH EDUCATION AND RESEARCH CENTERS (T42)
职业安全健康教育研究中心(T42)
- 批准号:
10407928 - 财政年份:2020
- 资助金额:
$ 13.63万 - 项目类别:
OCCUPATIONAL SAFETY AND HEALTH EDUCATION AND RESEARCH CENTERS (T42)
职业安全健康教育研究中心(T42)
- 批准号:
10044196 - 财政年份:2020
- 资助金额:
$ 13.63万 - 项目类别:
Exposure Assessment, Biomarkers and Metabolomics FC
暴露评估、生物标志物和代谢组学 FC
- 批准号:
8830361 - 财政年份:2015
- 资助金额:
$ 13.63万 - 项目类别:
Diesel Exposure in Mines: Biomarkers in Urine and Realtime Air Monitoring
矿井中的柴油暴露:尿液和实时空气监测中的生物标志物
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8737266 - 财政年份:2013
- 资助金额:
$ 13.63万 - 项目类别:
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