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Ion Channels Gordon Research Conferences & Seminar

离子通道戈登研究会议

基本信息

批准号：
9991020
负责人：
Brad S. Rothberg
金额：
$ 1.5万
依托单位：
GORDON RESEARCH CONFERENCES
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-08-01 至 2022-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9991020
关键词：
Academia Address Area Arrhythmia Bacteria Biology Biomedical Research Brain Catalysis Cells Chlorides Collaborations Communities Computational Biology Computer Models Coupling Creativeness Cryoelectron Microscopy Cystic Fibrosis Data Diabetes Mellitus Disabled Persons Disease Endocrine Environment Epilepsy Eye Fees Fertilization Fostering Functional disorder Gene Expression Regulation Genes Genetic Germ Cells Glutamates Goals Health Hour Human Human Biology Immune Industry International Ion Channel Knowledge Massachusetts Microbial Biofilms Modality Molecular Molecular Structure Muscle Nerve Nervous system structure Organ Pain Paralysed Participant Pharmacotherapy Physiological Physiology Proteins Reproducibility Request for Proposals Research Research Personnel Role Science Scientific Advances and Accomplishments Scientist Sensory Series Signal Transduction Structure System Taste Perception Time Tissues Touch sensation Travel Underrepresented Minority United States National Institutes of Health Woman Work X-Ray Crystallography base career career development college heart pharmacology human disease improved innovation meetings nervous system disorder novel therapeutics painful neuropathy posters programs success symposium therapeutic target

项目摘要

Project Summary/Abstract This proposal requests partial support for an internationally-attended meeting on Ion Channels, as part of the Gordon Research Conference (GRC) series, to be held at Mount Holyoke College in South Hadley, Massachusetts, July 12 – 17, 2020. The broad and long-term goal of the conference is to increase our understanding of the structure, function and physiological roles of ion channels, their targeting by next-generation therapeutics, as well as the molecular basis of channel dysfunction in disease. The 2020 iteration of the meeting will assemble presentations on the latest advances in structure determination, functional analysis, computational modelling and targeted gene editing, with an eye toward understanding physiological mechanisms and treatment of disease. The specific aims of this meeting will be to convene roughly 45 speakers and discussion leaders that represent critical areas of ion channel research, with a maximum total of 200 participants, for a five-day meeting in a secluded setting. The program will have nine platform sessions that address current issues in ion channel mechanisms in human health and disease, which will all incorporate late-breaking talks to be determined shortly before the conference, to promote discussion on the newest cutting-edge research. Ample time will be allotted during the platform sessions for discussion and exchange of ideas. In addition, four poster sessions will allow all participants to present their latest research and further scientific discussions. The significance of this proposal is that the Ion Channels GRC is widely regarded as a key, established conference to fertilize ideas and research in the community of ion channel biologists. Indeed, the small size and intensive discussions facilitated by the Ion Channels GRC make it uniquely important for the catalysis of new ideas and directions among the participants. The goals of the meeting are to advance our understanding of ion channels as key players in the function of nerve, muscle, sensory organs and other systems, and as therapeutic targets for the cure and treatment of human disease.

项目总结/摘要该提案要求部分支持国际参与的离子通道会议，作为戈登研究会议（GRC）系列，将在南哈德利的霍利奥克山学院举行，马萨诸塞州，2020年7月12日至17日。会议的广泛和长期目标是增加我们的了解离子通道的结构，功能和生理作用，它们的目标是下一代治疗学，以及疾病中通道功能障碍的分子基础。会议的2020年迭代将汇集有关结构测定，功能分析，计算建模和靶向基因编辑，着眼于了解生理机制和治疗疾病。本次会议的具体目标是召集大约45名发言人和讨论负责人代表离子通道研究的关键领域，最多200名参与者，为期五天，在一个僻静的地方见面该计划将有九个平台会议，解决当前的问题，离子在人类健康和疾病的渠道机制，这将全部纳入最新突破会谈有待确定在会议前不久，促进对最新前沿研究的讨论。足够的时间在平台届会期间分配的用于讨论和交流想法的资源。此外，四个海报会议将允许所有参与者介绍他们的最新研究和进一步的科学讨论。其意义建议是，离子通道GRC被广泛认为是一个关键的，既定的会议，以丰富思想，离子通道生物学家社区的研究。事实上，小规模和密集的讨论促进了由离子通道GRC使其具有独特的重要性，为催化新的想法和方向之间的参与者会议的目标是促进我们对离子通道的理解，离子通道是生物学中的关键参与者。神经，肌肉，感觉器官和其他系统的功能，并作为治疗目标的治愈和治疗人类疾病。