NIMH, NICHD, AND NINDS BRAIN AND TISSUE REPOSITORY

NIMH、NICHD 和 NINDS 脑和组织存储库

• 批准号: 9123476
• 负责人: RASHED NAGRA
• 金额: $ 40.55万
• 依托单位: SEPULVEDA RESEARCH CORPORATION
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-01 至 2015-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9123476
• 关键词: Award; Biological; Biopsy; Birth; Blood; Brain; Catchment Area; Cause of Death; Centers for Disease Control and Prevention (U.S.); Cephalic; Cessation of life; Child; Child health care; Classification Scheme; Clinical; Clinical Data; Code; Collaborations; Collection; Common Data Element; Communities; Comorbidity; Contractor; Contracts; Data; Date of birth; Diagnosis; Diagnostic; Disease; Documentation; Educational Background; Ethnic Origin; Evaluation; Family; Fetal Tissues; Fibroblasts; First Degree Relative; Future; Genetic screening method; Gestational Age; Goals; Grant; Hereditary Disease; Hospitalization; Human; Human Development; Image; Institutes; International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10); Judgment; Liver; Magnetic Resonance Imaging; Medical; Mental disorders; National Institute of Child Health and Human Development; National Institute of Mental Health; Neonatal; Neuraxis; Neurodevelopmental Disorder; Onset of illness; Patient advocacy; Pharmaceutical Preparations; Population; Process; Qualifying; Recording of previous events; Recruitment Activity; Reporting; Research; Research Personnel; Sampling; Services; Site; Skin; Source; Specialist; Specimen; Stroke; Substance abuse problem; Time; Tissue Banks; Tissues; United States National Institutes of Health; Urine; advocacy organizations; base; brain tissue; disorder control; experience; human disease; nervous system disorder; neuropsychiatry; outreach; prenatal; repository

The National Institute of Mental Health (NIMH), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), and the National Institute of Neurological Diseases and Stroke (NINDS), National Institutes of Health, seek to make human brain tissue and biospecimen samples more widely available for research on neurological, psychiatric, and neurodevelopmental disorders. The objective of this initiative is to increase availability of human disease and control biospecimens, increase proactive involvement of the disease advocacy and patient communities, and more efficiently acquire, curate, store, and distribute these tissues with the ultimate goal of reducing the burden of nervous system disorders. In order to do so, the NIH intends to establish multiple contract collection sites (i.e., the NIH Brain and Tissue Repositories (NBTR)) to provide services that will actively acquire, receive, process, store, curate, preserve, and distribute central nervous system and related biological specimens (including fetal tissues) to qualified investigators. These services were previously provided through grants that have expired and/or will be expiring in the coming years. The NIH will now continue these existing services through competitively awarded contracts. New sources are also encouraged to compete.

美国国家精神卫生研究所（NIMH）、尤妮斯·肯尼迪·施莱佛国家儿童健康和人类发展研究所（NICHD）和美国国家神经疾病和中风研究所（NINDS），美国国家卫生研究院，寻求使人脑组织和生物标本样本更广泛地用于神经学、精神病学和神经发育障碍的研究。该倡议的目标是增加人类疾病和控制生物标本的可用性，增加疾病宣传和患者社区的积极参与，并更有效地获取，策划，储存和分发这些组织，最终目标是减轻神经系统疾病的负担。为了做到这一点，NIH打算建立多个合同收集站点（即，NIH脑和组织储存库（NBTR））提供主动获取、接收、处理、储存、管理、保存和分发中枢神经系统和相关生物标本（包括胎儿组织）给合格研究者的服务。这些服务以前是通过已经到期和/或将在未来几年到期的赠款提供的。NIH现在将通过竞争性授予的合同继续这些现有的服务。还鼓励新的来源参与竞争。