Network Management Core (NEMO) for the Pulmonary Trials Cooperative (PTC)

肺试验合作组织 (PTC) 的网络管理核心 (NEMO)

• 批准号: 8955861
• 负责人: FRANK SCIURBA
• 金额: $ 439.73万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-01 至 2020-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8955861
• 关键词: Accreditation; Address; American; Area; Bioinformatics; Budgets; Categories; Characteristics; Chronic; Chronic lung disease; Classification; Clinical; Clinical Data; Clinical Management; Clinical Services; Clinical Trials; Clinical Trials Data Monitoring Committees; Collaborations; Communication; Communities; Complex; Computerized Medical Record; Coordination and Collaboration; Data; Discipline; Disease; Documentation; Electronics; Enrollment; Ensure; Epidemiology; Evaluation; Foundations; Funding; Goals; Health Sciences; Inpatients; Institution; Institutional Review Boards; Investments; Leadership; Letters; Lung; Lung diseases; Measurement; Medical; Modeling; Morbidity - disease rate; Multicenter Studies; National Heart, Lung, and Blood Institute; Obstructive Sleep Apnea; Outcome; Outpatients; Pathologist; Patients; Physiological; Population; Principal Investigator; Productivity; Protocols documentation; Public Health; Recruitment Activity; Registries; Reporting; Request for Applications; Research; Research Infrastructure; Research Personnel; Structure; Supervision; System; Techniques; Testing; Therapeutic Agents; Time; Tissue Banking; Tissue Banks; United States National Institutes of Health; Universities; Work; base; biobank; cohort; college; cooperative study; design; drug distribution; experience; innovation; interest; meetings; mortality; novel; novel strategies; novel therapeutics; operation; patient population; programs; public health relevance; response

 DESCRIPTION (provided by applicant): In response to Request for Applications (RFA) RFA-HL-15-016, the University of Pittsburgh proposes to establish the Network Management Core (NEMO) of the Pulmonary Trials Cooperative (PTC). In addition to the NEMO, the PTC will include up to three Protocol Leadership Groups (PLGs), a Data and Safety Monitoring Board (DSMB), representatives from the NHLBI, a Steering Committee (with a chair appointed by the NHLBI), and various subcommittees to the Steering Committee. The NEMO will bring together substantive and management expertise. The Principal Investigators, Dr. Stephen Wisniewski and Frank Sciurba are experienced in the conduct and administration of complex multi-center studies. An exemplary team of co- investigators with expertise across the spectrum of lung diseases have been identified and well established relationships within the lung community to facilitate access to the necessary subject populations. With this experience comes an understanding of the responsibilities of the NEMO for the PTC as well as an understanding of the commitments associated with being the NEMO for a large collaborative network. The overarching goal of the NEMO is to encourage and facilitate collaboration, sharing, interaction, and research within the PTC. The specific aims of the NEMO are: Aim 1. Provide scientific input on the design, conduct, and analysis of PTC studies. Aim 2. Provide administrative support for the PTC Aim 3. Implement systems to ensure the highest quality studies Aim 4. Develop systems to provide seamless communications among PTC investigators Aim 5. Serve as a biorepository for the PTC Aim 6. Support future research endeavors of the PTC.

 描述（由申请人提供）：为了响应申请请求（RFA）RFA-HL-15-016，匹兹堡大学提议建立肺试验合作组织（PTC）的网络管理核心（NEMO）。除NEMO外，PTC还将包括最多三个方案领导小组（PLG）、一个数据和安全监测委员会（DSMB）、NHLBI的代表、一个指导委员会（主席由NHLBI任命）和指导委员会的各个小组委员会。国家经济管理办公室将汇集实务和管理方面的专门知识。主要研究者Stephen Wisniewski博士和Frank Sciurba在开展和管理复杂的多中心研究方面经验丰富。已经确定了一个具有跨肺部疾病谱专业知识的合作研究者的示范团队，并在肺部社区内建立了良好的关系，以促进对必要受试者人群的访问。有了这些经验，就能理解NEMO对PTC的责任，也能理解作为NEMO对大型协作网络的承诺。 NEMO的首要目标是鼓励和促进PTC内部的协作、共享、互动和研究。国家经济管理组织的具体目标是：目标1。为PTC研究的设计、实施和分析提供科学投入。 目标二。为PTC Aim 3提供行政支持。实施系统，以确保最高质量的研究目标4。开发系统以提供PTC调查人员之间的无缝通信作为PTC Aim 6的生物储存库。支持PTC未来的研究工作。