Network Management Core (NEMO) for the Pulmonary Trials Cooperative (PTC)

肺试验合作组织 (PTC) 的网络管理核心 (NEMO)

• 批准号: 8955861
• 负责人: FRANK SCIURBA
• 金额: $ 439.73万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-01 至 2020-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8955861
• 关键词: Accreditation; Address; American; Area; Bioinformatics; Budgets; Categories; Characteristics; Chronic; Chronic lung disease; Classification; Clinical; Clinical Data; Clinical Management; Clinical Services; Clinical Trials; Clinical Trials Data Monitoring Committees; Collaborations; Communication; Communities; Complex; Computerized Medical Record; Coordination and Collaboration; Data; Discipline; Disease; Documentation; Electronics; Enrollment; Ensure; Epidemiology; Evaluation; Foundations; Funding; Goals; Health Sciences; Inpatients; Institution; Institutional Review Boards; Investments; Leadership; Letters; Lung; Lung diseases; Measurement; Medical; Modeling; Morbidity - disease rate; Multicenter Studies; National Heart, Lung, and Blood Institute; Obstructive Sleep Apnea; Outcome; Outpatients; Pathologist; Patients; Physiological; Population; Principal Investigator; Productivity; Protocols documentation; Public Health; Recruitment Activity; Registries; Reporting; Request for Applications; Research; Research Infrastructure; Research Personnel; Structure; Supervision; System; Techniques; Testing; Therapeutic Agents; Time; Tissue Banking; Tissue Banks; United States National Institutes of Health; Universities; Work; base; biobank; cohort; college; cooperative study; design; drug distribution; experience; innovation; interest; meetings; mortality; novel; novel strategies; novel therapeutics; operation; patient population; programs; public health relevance; response

 DESCRIPTION (provided by applicant): In response to Request for Applications (RFA) RFA-HL-15-016, the University of Pittsburgh proposes to establish the Network Management Core (NEMO) of the Pulmonary Trials Cooperative (PTC). In addition to the NEMO, the PTC will include up to three Protocol Leadership Groups (PLGs), a Data and Safety Monitoring Board (DSMB), representatives from the NHLBI, a Steering Committee (with a chair appointed by the NHLBI), and various subcommittees to the Steering Committee. The NEMO will bring together substantive and management expertise. The Principal Investigators, Dr. Stephen Wisniewski and Frank Sciurba are experienced in the conduct and administration of complex multi-center studies. An exemplary team of co- investigators with expertise across the spectrum of lung diseases have been identified and well established relationships within the lung community to facilitate access to the necessary subject populations. With this experience comes an understanding of the responsibilities of the NEMO for the PTC as well as an understanding of the commitments associated with being the NEMO for a large collaborative network. The overarching goal of the NEMO is to encourage and facilitate collaboration, sharing, interaction, and research within the PTC. The specific aims of the NEMO are: Aim 1. Provide scientific input on the design, conduct, and analysis of PTC studies. Aim 2. Provide administrative support for the PTC Aim 3. Implement systems to ensure the highest quality studies Aim 4. Develop systems to provide seamless communications among PTC investigators Aim 5. Serve as a biorepository for the PTC Aim 6. Support future research endeavors of the PTC.

 描述(由申请人提供)：针对申请申请(RFA)RFA-HL-15-016，匹兹堡大学建议建立肺试验合作社(PTC)的网络管理核心(NEMO)。除了NEMO，PTC还将包括多达三个议定书领导小组(PLGs)、一个数据和安全监测委员会(DSMB)、来自NHLBI的代表、一个指导委员会(由NHLBI任命一名主席)以及指导委员会的各个小组委员会。NEMO将汇集实质性和管理方面的专业知识。首席研究员斯蒂芬·维斯涅夫斯基博士和弗兰克·肖尔巴在进行和管理复杂的多中心研究方面经验丰富。已经确定了一支在各种肺部疾病领域拥有专业知识的模范协查小组，并在肺学界建立了良好的关系，以便利接触必要的受试者。通过这一经历，我们了解了NEMO对PTC的责任，以及作为NEMO对大型协作网络的承诺。NEMO的首要目标是鼓励和促进PTC内的合作、共享、互动和研究。NEMO的具体目标是：目标1.为PTC研究的设计、实施和分析提供科学投入。目标2.为技术合作中心目标提供行政支持3.实施系统以确保最高质量的研究目标4.开发系统以在技术合作中心调查人员之间提供无缝通信目标5.作为技术合作中心目标的生物信息库6.支持技术合作中心未来的研究努力