Network Management Core (NEMO) for the Pulmonary Trials Cooperative (PTC)

肺试验合作组织 (PTC) 的网络管理核心 (NEMO)

• 批准号: 8955861
• 负责人: FRANK SCIURBA
• 金额: $ 439.73万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-01 至 2020-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8955861
• 关键词: Accreditation; Address; American; Area; Bioinformatics; Budgets; Categories; Characteristics; Chronic; Chronic lung disease; Classification; Clinical; Clinical Data; Clinical Management; Clinical Services; Clinical Trials; Clinical Trials Data Monitoring Committees; Collaborations; Communication; Communities; Complex; Computerized Medical Record; Coordination and Collaboration; Data; Discipline; Disease; Documentation; Electronics; Enrollment; Ensure; Epidemiology; Evaluation; Foundations; Funding; Goals; Health Sciences; Inpatients; Institution; Institutional Review Boards; Investments; Leadership; Letters; Lung; Lung diseases; Measurement; Medical; Modeling; Morbidity - disease rate; Multicenter Studies; National Heart, Lung, and Blood Institute; Obstructive Sleep Apnea; Outcome; Outpatients; Pathologist; Patients; Physiological; Population; Principal Investigator; Productivity; Protocols documentation; Public Health; Recruitment Activity; Registries; Reporting; Request for Applications; Research; Research Infrastructure; Research Personnel; Structure; Supervision; System; Techniques; Testing; Therapeutic Agents; Time; Tissue Banking; Tissue Banks; United States National Institutes of Health; Universities; Work; base; biobank; cohort; college; cooperative study; design; drug distribution; experience; innovation; interest; meetings; mortality; novel; novel strategies; novel therapeutics; operation; patient population; programs; public health relevance; response

 DESCRIPTION (provided by applicant): In response to Request for Applications (RFA) RFA-HL-15-016, the University of Pittsburgh proposes to establish the Network Management Core (NEMO) of the Pulmonary Trials Cooperative (PTC). In addition to the NEMO, the PTC will include up to three Protocol Leadership Groups (PLGs), a Data and Safety Monitoring Board (DSMB), representatives from the NHLBI, a Steering Committee (with a chair appointed by the NHLBI), and various subcommittees to the Steering Committee. The NEMO will bring together substantive and management expertise. The Principal Investigators, Dr. Stephen Wisniewski and Frank Sciurba are experienced in the conduct and administration of complex multi-center studies. An exemplary team of co- investigators with expertise across the spectrum of lung diseases have been identified and well established relationships within the lung community to facilitate access to the necessary subject populations. With this experience comes an understanding of the responsibilities of the NEMO for the PTC as well as an understanding of the commitments associated with being the NEMO for a large collaborative network. The overarching goal of the NEMO is to encourage and facilitate collaboration, sharing, interaction, and research within the PTC. The specific aims of the NEMO are: Aim 1. Provide scientific input on the design, conduct, and analysis of PTC studies. Aim 2. Provide administrative support for the PTC Aim 3. Implement systems to ensure the highest quality studies Aim 4. Develop systems to provide seamless communications among PTC investigators Aim 5. Serve as a biorepository for the PTC Aim 6. Support future research endeavors of the PTC.

 描述（由申请提供）：响应匹兹堡大学的申请请求（RFA）RFA-HL-15-016，提议建立网络管理核心（NEMO）的肺部试验合作社（PTC）。除NEMO外，PTC还将包括最多三个协议领导小组（PLG），数据和安全监测委员会（DSMB），代表NHLBI，指导委员会（由NHLBI任命的主席）以及指导委员会的各种小组委员会代表。 Nemo将汇集实质和管理专业知识。主要研究人员Stephen Wisniewski和Frank Sciurba博士在复杂的多中心研究的行为和管理方面经验丰富。已经确定了肺部疾病范围内具有专业知识的共同投资者的典范团队，并在肺部社区内建立了良好的关系，以支持对必要的学科人群的访问。有了这一经验，就可以理解NEMO对PTC的责任，并了解与大型协作网络的NEMO相关的承诺。 NEMO的总体目标是鼓励和支持PTC内的协作，共享，互动​​和研究。 NEMO的具体目的是：AIM 1。对PTC研究的设计，行为和分析提供科学意见。 AIM 2。为PTC AIM 3提供行政支持。实施系统以确保最高质量的研究目标4。开发系统以在PTC研究人员之间提供无缝通信的目标5。作为PTC AIM 6的生物验证者6。支持PTC的未来研究努力。