ReThink HF: A novel multi-parameter sensor for heart failure remote monitoring

ReThink HF：一种用于心力衰竭远程监测的新型多参数传感器

• 批准号: 8782282
• 负责人: Reza Naima
• 金额: $ 18.83万
• 依托单位: RETHINK MEDICAL, INC.
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8782282
• 关键词: Adopted; Affect; Algorithms; American; Ankle; Body Weight Changes; Cardiac; Caregivers; Caring; Chest; Clinical; Data; Data Collection; Development; Devices; Diuresis; Early Diagnosis; Edema; Elderly; Enrollment; Event; FDA approved; Feedback; Fluid Balance; Goals; Heart Rate; Heart failure; Home environment; Hospitalization; Hospitals; Individual; Inpatients; Institutional Review Boards; Insurance; Lead; Learning; Liquid substance; Lower Extremity; Measurement; Measures; Metric; Monitor; Patient Monitoring; Patient Recruitments; Patients; Peripheral; Phase; Physicians; Physicians' Offices; Physiological; Population; Problem Solving; Quality of Care; Respiratory System; Sampling; Secure; Services; Signal Transduction; Staging; Symptoms; System; Technology; Telemetry; Time; Training; Validation; Vision; Weight; Wireless Technology; Wrist; aged; base; commercial application; cost; experience; heart rate variability; improved; innovation; insight; miniaturize; novel; prevent; prototype; public health relevance; respiratory; response; sensor; tool; trend

DESCRIPTION (provided by applicant): Heart failure effects 5.8 million individuals in the US and the costs associated are approaching $40 billion. The current clinical paradigm for managing heart failure patients is reactive and involves patient self-monitoring which suffers from poor compliance. Additionally, patients lack the tools to enable measurements of the relevant physiologic metrics, and the physicians have limited insight of the patient's real-time cardiac status. Our technology proposes to solve these problems by providing an inexpensive, non-invasive wrist-worn monitor which tracks the relevant parameters, provides proactive feedback to the patient and physician's office, and requires no interaction from the patient thus yielding a high level of compliance. This project will investigate the benefits of a novel, non-invasive multi-parameter sensor with telemetry for monitoring patients with heart failure. The technology can continuously monitor heart rate, heart rate variability, respiratory rate, activity levels, and fluid levels. We will incorporate these metrics into a proven algorithm (50% reduction in hospitalizations in 1,200 patients over 6 months) for early detection of cardiac decompensation with a goal of further improving the predictive ability of the algorithm. Our goals are to simplify the management of heart failure while improving the quality of care of the patients and reducing the associated costs.

描述（由申请人提供）：心力衰竭影响美国 580 万人，相关费用接近 400 亿美元。目前治疗心力衰竭患者的临床模式是反应性的，涉及患者自我监测，但依从性较差。此外，患者缺乏测量相关生理指标的工具，并且医生对患者实时心脏状态的了解有限。我们的技术建议通过提供一种廉价、非侵入性腕戴式监测器来解决这些问题，该监测器可跟踪相关参数，向患者和医生办公室提供主动反馈，并且无需患者交互，从而产生高水平的依从性。该项目将研究一种具有遥测功能的新型非侵入性多参数传感器在监测心力衰竭患者方面的优势。该技术可以连续监测心率、心率变异性、呼吸频率、活动水平和体液水平。我们将把这些指标纳入经过验证的算法（6 个月内 1,​​200 名患者的住院率减少 50%），以便及早发现心脏代偿失调，目标是进一步提高算法的预测能力。我们的目标是简化心力衰竭的治疗，同时提高患者的护理质量 并降低相关成本。