ANTIMICROBIAL COPPER ALLOY COATINGS FOR CONTACT ENVIRONMENTS

适用于接触环境的抗菌铜合金涂层

• 批准号: 8714799
• 负责人: Joshua Caris
• 金额: $ 14.89万
• 依托单位: MESOCOAT ADVANCED COATING TECH
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-22 至 2015-06-21
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8714799
• 关键词: Address; Alloys; Anti-Bacterial Agents; Antimicrobial Resistance; Appearance; Area; Behavior; Cereals; Characteristics; Chemicals; Complex; Copper; Corrosion; Data; Development; Dimensions; Drug Formulations; Environment; Evaluation; Exposure to; Family; Film; Food; Future; Gases; Goals; Health; Healthcare; Heating; Hospitals; Indoor Air Quality; Industry; Infection; Life; Literature; Mechanics; Medical; Medical Device; Metals; Methods; Oils; Onset of illness; Output; Pharmacologic Substance; Phase; Porosity; Process; Property; Public Health; Publications; Research; Research Infrastructure; Resistance; Restaurants; Risk; Risk Reduction; Sampling; Schools; Series; Shapes; Simulate; Small Business Innovation Research Grant; Solutions; Spottings; Stainless Steel; Steel; Sterilization; Surface; Surface Tension; Technology; Temperature; Touch sensation; Tube; Viscosity; Welding; Workplace; antimicrobial; base; commercialization; cost; experience; health related quality of life; implantable device; improved; interest; nanoparticle; operation; prevent; programs; public health relevance; research study; scale up; screening; surface coating; technology development

DESCRIPTION: This Small Business Innovation Research Phase I project shows great intellectual merit. The antimicrobial properties of copper-based alloys continue to be a topic of research interest, and there are no current publications detailing the mechanical properties, corrosion resistance, and anti-microbial characteristics of copper-based alloy bi-layers. Pending a successful Phase I research program, high wear and corrosion-resistant copper alloys in the form of copper-based alloys will be evaluated. The broader impacts of this project are manifold. An inherently anti- bacterial coating for hospital applications has wide-ranging effects on degree of health care and mitigation of costs incurred through infection associated with hospital practice. Common examples include: infections from biomedical implants, degradation of protective coatings on buildings, fouling of food products, loss of efficacy of pharmaceutical formulations, and many more. A growing body of health literature is promoting the use of copper-based alloys for consumer applications, and copper alloy coatings on conventional steel substrates will prove viable, low cost alternatives to the current copper alloys in structural applications. MesoCoat is commercializing its CermaClad" high rate cladding process for the oil and gas and infrastructure industries, and this program will explore the extension of this technology into the antimicrobial surfaces (medical devices and indoor air quality) industry verticals via copper- cladding of steel substrates.

描述：这个小企业创新研究第一阶段项目显示了巨大的智力价值。铜基合金的抗微生物性能仍然是研究兴趣的主题，并且目前没有详细描述铜基合金双层的机械性能、耐腐蚀性和抗微生物特性的出版物。在第一阶段研究计划取得成功之前，将对铜基合金形式的高耐磨和耐腐蚀铜合金进行评估。该项目的广泛影响是多方面的。用于医院应用的固有抗菌涂层对医疗保健的程度和减轻与医院实践相关的感染引起的成本具有广泛的影响。常见的例子包括：生物医学植入物的感染、建筑物上保护涂层的降解、食品的污染、药物制剂的功效损失等等。越来越多的健康文献正在促进铜基合金在消费应用中的使用，并且在传统钢基材上的铜合金涂层将证明是结构应用中当前铜合金的可行的、低成本的替代品。MesoCoat正在将其CermaClad”高速覆层工艺商业化，用于石油和天然气以及基础设施行业，该计划将探索通过钢基材的铜覆层将该技术扩展到抗菌表面（医疗器械和室内空气质量）行业垂直领域。