Ketamine therapy among patients with treatment-resistant depression: a randomised, double-blind, placebo-controlled trial

难治性抑郁症患者的氯胺酮治疗：一项随机、双盲、安慰剂对照试验

• 批准号: nhmrc : 1105089
• 负责人: A/Pr Maree Hackett
• 金额: $ 141.83万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/ketamine-therapy-patients-controlled-trial/662803
• 关键词: Ketamine; therapy; among; patients; treatment

In the last decade, there have been reports of powerful antidepressant effects after a single injection of anaesthetic ketamine, with dramatic (though shortlasting) effects within 24 hours. This will be the first controlled study to test whether a course of repeated ketamine treatments, given over 4 weeks, is effective and safe in treating depression.

在过去的十年中，有报道称，单次注射麻醉剂氯胺酮后会产生强大的抗抑郁作用，在24小时内产生显著（尽管持续时间很短）的效果。这将是第一项对照研究，旨在测试4周内重复氯胺酮治疗疗程是否对治疗抑郁症有效且安全。