2015 Fertilization and Activation of Development Gordon Research Conference & Gordon Research Seminar

2015年施肥与发育激活戈登研究会议

• 批准号: 8975378
• 负责人: GARY M WESSEL
• 金额: $ 0.6万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-02 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8975378
• 关键词: Address; American; Andrology; Area; Award; Biochemical; Biological; Biological Phenomena; Biology; Biomedical Research; Cellular biology; Collaborations; Contraceptive methods; Data; Development; Disabled Persons; Embryo; Embryonic Development; Environment; Event; Faculty; Fertilization; Fertilization in Vitro; Fostering; Funding; Future; Gametogenesis; Generations; Germ Cells; Goals; Health Sciences; Home environment; Human; In Vitro; Individual; Infertility; Institutes; International; Lead; Mammals; Medicine; Mentors; Minority; Molecular; Molecular Biology; Nature; New Hampshire; Nobel Prize; Organism; Participant; Physiological; Physiology; Policies; Postdoctoral Fellow; Preparation; Process; Publishing; Recurrence; Reproduction; Reproductive Biology; Request for Applications; Research; Research Personnel; Running; Schools; Science; Scientist; Series; Societies; Staging; Stem cells; Thinking; Time; Training; Woman; Work; base; career; career development; collaborative environment; design; egg; ethnic minority population; graduate student; induced pluripotent stem cell; innovation; interest; meetings; peer; professional atmosphere; public health relevance; receptor; reproductive; sperm cell; success; symposium; synthetic biology

 DESCRIPTION (provided by applicant): This R13 application requests funds to support the 21st iteration of the Gordon Research Conference (GRC) on Fertilization and Activation of Development. This 2015 GRC addresses the myriad of biological phenomena that impact the merger of the two gametes and the initiation of the development of a new individual. It integrates broad research perspectives, including the biochemical, biophysical, molecular, cellular, physiological, evolutionary, and organismal aspects of the phenomenon. Awarding of the 2010 Nobel Prize in Physiology or Medicine to Dr. Robert G. Edwards for the development of in vitro fertilization underscores the significance of this area of biology and biomedical research, and the more recent Nobel Award (2012) for induced pluripotent stem cells. These induced stems cells were recently shown to be capable of forming eggs and sperm, opening huge scientific and societal potential. The major investigator in this feat will be one of the speakers at the Conference. The Fertilization and Activation of Development GRC is the only meeting worldwide focusing specifically on the biology of fertilization. Remarkable progress has been made in the field since the last Conference; including identification of a receptor on eggs (Juno) for sperm (Izumo) that was published this year in Nature, and the generation of eggs and sperm in vitro. The lead authors of these studies have agreed to speak at this conference and the flurry of activity in these and other areas promises to make for a very exciting series of discussions. The keynote address will be presented by Dr. Ron Weiss (MIT) on synthetic biological approaches in reproduction. Dr. Weiss is a leader in the field of synthetic biology, and excellent speaker, and will help push the conferees into thinking from a different perspective. Added to this format is the second Gordon Research Seminar on Fertilization and Activation of Development. The two-day seminar preceding the conference has the objective to attract young investigators in the field of gamete research and fertilization. 2013's initial Seminar was wildly successful and we plan on building on that success this year. We anticipate this seminar being a continuous and important building mechanism for the future of this rapidly moving field. The overarching goals for this conference are to create a forum for presentation and discussion of cutting-edge research, to foster a vibrant and interactive atmosphere to facilitate scientific interactions, and to provide a supportive environment for young investigators as well as participants from groups traditionally underrepresented in the sciences, including women, underrepresented ethnic minorities, and people with disabilities.

 描述(申请人提供)：此R13申请申请资金，以支持第21次戈登研究会议(GRC)关于受精和激活发展。2015年的GRC讨论了影响两个配子的合并和新个体发育的无数生物现象。它综合了广泛的研究视角，包括生化、生物物理、分子、细胞、生理、进化和生物方面的现象。将2010年诺贝尔生理学或医学奖授予罗伯特·G·爱德华兹博士，以表彰体外受精的发展，突显了这一生物学和生物医学研究领域的重要性，以及最近因诱导多能干细胞而获得的诺贝尔奖(2012年)。这些诱导的干细胞最近被证明能够形成卵子和精子，开启了巨大的科学和社会潜力。这一壮举的主要调查者将是本会议的发言者之一。受精与发展激活全球研究中心是世界上唯一专门关注受精生物学的会议。自上次会议以来，该领域取得了显著进展；包括今年发表在《自然》杂志上的卵子上精子受体(Juno)的鉴定(Izumo)，以及卵子和精子的体外产生。这些研究的主要作者已经同意在这次会议上发言，这些领域和其他领域的一系列活动有望促成一系列非常令人兴奋的讨论。主旨演讲将由Ron Weiss博士(麻省理工学院)就生殖中的合成生物学方法发表。韦斯博士是合成生物学领域的领导者，也是出色的演讲者，他将帮助与会者从不同的角度进行思考。在此基础上增加了第二届戈登受精和激活发育研究研讨会。会议前为期两天的研讨会旨在吸引配子研究和受精领域的年轻研究人员。2013年的S首次研讨会非常成功，我们计划今年在这一成功的基础上再接再厉。我们期待这次研讨会成为这一快速发展领域未来的一个持续和重要的建设机制。这次会议的总体目标是创建一个介绍和讨论前沿研究的论坛，营造活跃和互动的氛围，促进科学互动，并为青年研究人员以及在科学界传统上代表性较低的群体的参与者提供一个支持性环境，包括妇女、代表性不足的少数族裔和残疾人。