IMPACT OF DIET, EXERCISE AND LIFESTYLE ON FERTILITY: THE IDEAL FERTILITY STUDY

饮食、运动和生活方式对生育力的影响：理想生育力研究

• 批准号: 9169607
• 负责人: ERICA JOHNSTONE
• 金额: $ 303.89万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-01 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9169607
• 关键词: Acne; Androgens; Biochemical; Biological Markers; Caffeine; Carbohydrates; Clinical; Contractor; Couples; Data Sources; Diet; Dietary Fiber; Dietary Practices; Dietary intake; Disease; Dual-Energy X-Ray Absorptiometry; Evaluation; Fatty acid glycerol esters; Female; Fertility; Fertility Study; Folic Acid; Future; Goals; Gynecologic; Hirsutism; Leptin; Life Style; Measurement; Measures; Mediterranean Diet; Menstrual cycle; Metabolic; Molecular Weight; Morphology; Obesity; Outcome; Ovarian; Participant; Phenotype; Physical activity; Phytoestrogens; Pregnancy; Pregnancy Outcome; Randomized; Regulation; Resources; Role; Stress; Supplementation; Vitamin D; Woman; Women' s Role; Zinc; adiponectin; base; cohort; diet and exercise; endometriosis; follow-up; interest; leptin receptor; lifestyle factors; male; prospective; sample collection

The goal of the proposed study is to evaluate the impacts of modifiable lifestyle factors on fertility in the context of a couple-based approach across a spectrum of fertility and treatment. Female partners of FAZST participants provide a unique and valuable resource, bringing about an opportunity to follow a large, prospective cohort of women undergoing fertility treatment, while leveraging precious resources to create a rich data source for future studies. In the proposed IDEAL study, the contractor shall extend follow-up of approximately 1200 of the female FAZST (Folic Acid and Zinc Supplementation Trial) participants to 12 months post randomization of the male partner and complete additional detailed assessments and bio specimens collection.

拟议研究的目标是在一系列生育和治疗的基于夫妇的方法的背景下，评估可改变的生活方式因素对生育的影响。 FAZST 参与者的女性伴侣提供了独特而宝贵的资源，带来了跟踪大量接受生育治疗的前瞻性女性的机会，同时利用宝贵的资源为未来的研究创建丰富的数据源。 在拟议的 IDEAL 研究中，承包商应将大约 1200 名女性 FAZST（叶酸和锌补充剂试验）参与者的随访时间延长至男性伴侣随机分组后 12 个月，并完成额外的详细评估和生物样本收集。