Neuroendocrine Investigators and Mentoring in the field of Alcohol Research

酒精研究领域的神经内分泌研究人员和指导

• 批准号: 8902743
• 负责人: GARY S WAND
• 金额: $ 17.79万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2016-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8902743
• 关键词: Accounting; Affect; Alcohol dependence; Alcohols; Amphetamines; Animals; Award; Brain; Chemicals; Clinical Research; Consumption; Data; Data Analyses; Data Collection; Dependency; Development; Doctor of Philosophy; Dopamine; Ethical Issues; Evaluation; Familiarity; Female; Foundations; Functional disorder; Funding; Generations; Glucocorticoids; Goals; Gonadal Steroid Hormones; Health Policy; Hormonal; Human; Human Genetics; Hydrocortisone; Individual; Individual Differences; Informed Consent; Interview; Laboratories; Life; Manuscripts; Measures; Mentored Patient-Oriented Research Career Development Award; Mentors; Mentorship; Neurosecretory Systems; Peptides; Performance; Persons; Pharmaceutical Preparations; Positioning Attribute; Positron-Emission Tomography; Preparation; Process; Psyche structure; Relapse; Research; Research Design; Research Personnel; Rewards; Risk; Rodent; Signal Transduction Pathway; Stress; Stress Tests; Substance Use Disorder; Technology; Testing; Testosterone; Training; Training Programs; Universities; Woman; Work; Writing; addiction; alcohol effect; alcohol research; alcohol response; alcohol sensitivity; alcohol use disorder; anxiety-like behavior; base; career; clinical investigation; cost; design; drug craving; drug of abuse; drug reward; high risk; human subject; interest; knowledge base; male; meetings; men; neurochemistry; neurosteroids; pre-clinical; programs; protocol development; response; skills; stressor; theories; transmission process

DESCRIPTION (provided by applicant): Dr. Wand is a neuroendocrinologist trained in both preclinical and clinical investigation. He works with a multidiscipline team and has acquired hormonal, neurochemical, genetic and human and rodent laboratory skills to pursue his research agenda. Currently Dr. Wand is principle investigator of 4 studies: 2 R01s, 1R03 and a R37 (no cost extension). He is also co- investigator on 6 other R01 awards. Dr. Wand has successfully been the scientific mentor for 16 MD and PhD trainees over the last 12 years. Three of his trainees received K23 awards on their first submission. All 16 trainees are in academics with their own funding or work in health policy positions. Dr. Wand has received awards for mentoring and Johns Hopkins University's highest award for bringing diversity to its training programs. Dr. Wand proposes to initially mentor 5 trainees. He anticipates mentoring approximately 2 additional trainees per year for the life of the award. He participates in multiple programs providing ample opportunities to identify promising trainees to mentor. Dr. Wand's mentoring program is designed to provide animal and human research trainees with a common knowledge base in alcohol theory, research design, data analysis strategies, ethical issues in pre-clinical and clinical research, and grantsmanship skills. In addition, each trainee receives more intensive individual training consistent with his/her special interests. These aspects include hypothesis generation, protocol development, and data analysis. For human investigators he covers human subjects considerations (including the process of obtaining informed consent), subject recruitment, interviewing, data collection, data cleaning, analysis, presentation and manuscript preparation. A primary goal of the mentoring is to enable trainees to develop writing and data analytic skills, as well as familiarity with new research technologies. Each trainee will receive quarterly formal review of goals and progress for performance evaluation and for career guidance. Each trainee meets weekly with one-on-one where he discusses research progress and goes over data, manuscript and reviews/chapters and any other pertinent issues. Individual mentorship provides the foundation for the training program.

描述（由申请人提供）：Dr. Wand是一名接受过临床前和临床研究培训的神经内分泌学家。他与一个多学科的团队合作，并获得了激素，神经化学，遗传和人类和啮齿动物实验室的技能，以追求他的研究议程。目前，Wand博士是4项研究的主要研究者：2项R 01、1 R 03和1项R37（无费用延期）。他也是其他6个R 01奖项的共同调查员。在过去的12年里，Wand博士成功地成为了16名MD和PhD学员的科学导师。他的三名学员在第一次提交时就获得了K23奖。所有16名受训人员都是有自己资金的学者或在卫生政策职位上工作。万德博士因其指导和约翰霍普金斯大学为培训项目带来多样性而获得最高奖。Wand博士建议最初指导5名学员。他预计，在该奖项的生命周期内，每年将指导大约2名额外的学员。他参加了多个项目，提供了充足的机会来确定有前途的学员进行指导。Wand博士的指导计划旨在为动物和人类研究受训者提供酒精理论，研究设计，数据分析策略，临床前和临床研究中的伦理问题以及granimetry技能的共同知识基础。此外，每个受训者还接受与其特殊兴趣相一致的强化个人培训。这些方面包括假设生成、方案制定和数据分析。对于人类研究者，他涵盖了人类受试者的考虑因素（包括获得知情同意的过程）、受试者招募、采访、数据收集、数据清理、分析、演示和手稿准备。指导的主要目标是使学员能够发展写作和数据分析技能，以及熟悉新的研究技术。每名受训人员每季度将接受关于目标和进展情况的正式审查，以进行业绩评价和职业指导。每个受训者每周一对一会面，讨论研究进展，审阅数据、手稿和评论/章节以及任何其他相关问题。个人指导为培训计划提供了基础。