Clinical Trials Network: Pacific Northwest Node

临床试验网络：太平洋西北节点

• 批准号: 9005952
• 负责人: DENNIS Michael DONOVAN
• 金额: $ 37.54万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-01-10 至 2015-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9005952
• 关键词: Admission activity; Adoption; Affect; Alaska; Alcohol abuse; Alcohol or Other Drugs use; American Indian and Alaska Native; Analgesics; Area; Behavioral; Clinical; Clinical Research; Clinical Trials; Clinical Trials Network; Communities; Community Outreach; Complement; Consultations; Country; Deltastab; Development; Drug abuse; Effectiveness; Ensure; Evidence based treatment; Faculty; Funding; Future; Geographic Locations; Goals; Health; Health Personnel; Health Policy; Healthcare; Heroin; High Prevalence; Idaho; Indian reservation; Individual; Institutes; Institution; Intervention; Intervention Trial; Investments; Life; Logistics; Medical; Mental Health; Mental disorders; Methamphetamine; Mission; Modification; Montana; Multi-Institutional Clinical Trial; Narcotics; National Institute of Drug Abuse; Outreach Research; Pacific Northwest; Patients; Pharmaceutical Preparations; Physicians; Policy Maker; Population; Poverty; Primary Health Care; Principal Investigator; Process; Protocols documentation; Provider; Public Health; Quality of Care; Research; Research Infrastructure; Research Institute; Research Personnel; Reservations; Risk; Rural; Rural Community; Rural Health; Science; Structure; Substance abuse problem; Technology Transfer; Therapeutic Effect; Training; Training and Infrastructure; Translational Research; Translations; Universities; Washington; Work; Wyoming; Youth; addiction; base; community based treatment; economic outcome; experience; frontier; geographic population; health economics; improved; knowledge base; meetings; methamphetamine abuse; methamphetamine use; metropolitan; patient population; prescription opiate; prevent; programs; public health priorities; rural area; social; social stigma; substance abuse treatment; suburb; translational health science; treatment program; urban area; woman health professional; young adult; young woman

DESCRIPTION (provided by applicant): This multiple-Pi, multiple-institution application for the competing renewal of the Pacific Northwest (PNW) Node of the NIDA Clinical Trials Network, submitted jointly by the University of Washington and Washington State University (WSU), has the primary aim of continuing the Node's active support of the CTN's mission to "improve the quality of drug abuse treatment throughout the country using science as the vehicle", to conduct studies of the therapeutic effect of behavioral, pharmacological, and combined/integrated treatment interventions in rigorous, multi-site clinical trials to determine effectiveness across a broad range of community-based treatment settings and diversified patient populations, and to ensure the transfer of research results to physicians, clinicians, providers, policy makers, and patients. To meet these objectives, the PNW Node proposes to: 'Maintain/expand the effective, bidirectional partnerships among researchers, substance abuse treatment and healthcare providers, and policy makers that predate our entry into the CTN; 'Maintain/expand our highly successful, well-established treatment research infrastructure; 'Expand the Node's geographical reach, working with the CTSA-funded Institute of Translational Health Sciences (ITHS), to include the WWAMI region (Washington, Wyoming, Alaska, Montana, and Idaho); 'Expand the Node's ethnic and demographic diversity by broadening the types of affiliated programs, expanding our focus on American Indians/Alaska Natives, and concentrating on rural communities/programs through our partnership with WSU's Program of Excellence on Rural Mental Health and Substance Abuse Treatment; Enhance the Node's capacity to conduct trials and respond more rapidly to shifting and emerging public health priorities by adding a number of larger, highly research-experienced, medically and psychiatrically focused partner organizations to complement our affiliated community-based substance abuse treatment programs; 'Augment the clinical research expertise of the Node by adding a number of new affiliated Investigators; 'Expand the Node's network of dissemination partners in order to provide research translation and training to a wider geographic and professional audience of providers, especially in primary care and rural settings. This new structure will allow us to capitalize on progress we have made and will enable us to continue to make significant contributions to the CTN's mission in the future.

描述(由申请人提供)：这份由华盛顿大学和华盛顿州立大学(WSU)联合提交的NIDA临床试验网络太平洋西北(PNW)节点竞相更新的多PI、多机构申请，主要目的是继续该节点积极支持CTN的使命，即“以科学为载体提高全国药物滥用治疗的质量”，在严格、多地点的临床试验中对行为、药理学和联合/综合治疗干预的治疗效果进行研究，以确定在广泛的基于社区的治疗环境和多样化的患者群体中的有效性。并确保将研究成果转移给医生、临床医生、提供者、政策制定者和患者。为了实现这些目标，PNW节点建议：“保持/扩大我们加入CTN之前研究人员、药物滥用治疗和医疗保健提供者以及政策制定者之间有效的双向伙伴关系；‘保持/扩大我们非常成功、成熟的治疗研究基础设施；’扩大节点的地理覆盖范围，与CTSA资助的翻译健康科学研究所(ITHS)合作，将WWAMI地区(华盛顿州、怀俄明州、阿拉斯加州、蒙大拿州和爱达荷州)包括在内；通过扩大附属项目的类型，扩大我们对美洲印第安人/阿拉斯加原住民的关注，并通过我们与西斯加州州立大学农村精神健康和药物滥用治疗卓越计划的合作，扩大Node的种族和人口多样性；通过增加一些规模更大、具有高度研究经验、医学和精神病学重点的合作伙伴组织，以补充我们附属的社区药物滥用治疗项目，增强Node进行试验的能力，并更快地对不断变化和出现的公共卫生优先事项做出反应；通过增加一些新的附属调查人员，增强Node的临床研究专业知识；‘扩大节点的传播合作伙伴网络，以便向更广泛的地理和专业提供者受众提供研究翻译和培训，特别是在初级保健和农村环境中。这一新的结构将使我们能够利用我们所取得的进展，并使我们能够继续为反恐委员会今后的任务作出重大贡献。