Prediction of CVD Risk in Veterans

描述(由申请人提供)： 我们建议评估心血管疾病(CVD)风险评估在没有癌症或其他重大疾病的退伍军人中的作用，并比较使用ATP4的美国国家指南评估与由VISN 1和VISN 7开发的VA特定配方的效用。将使用的核心变量包括传统的风险因素，如年龄、性别、种族、血压、吸烟、胆固醇、高密度脂蛋白和糖尿病状况。此外，我们建议确定评估患有糖尿病的退伍军人和已经经历过心血管疾病事件的退伍军人心血管风险的最佳方法。我们将评估ATP4估计方程在退伍军人中的精确度和准确性，并分别使用ATP4变量建立CVD风险方程，以评估估计退伍军人CVD风险的最佳方法。这项对退伍军人心血管疾病风险的关键评估旨在提供有效和方便的风险评估工具-未来可以纳入门诊退伍军人的临床护理，并已 在退伍军人管理局内指导心血管疾病预防治疗的潜力，以便能够协调资源，适当干预高危退伍军人的心血管预防服务，以发展未来的心血管疾病事件。这项建议与危险行为(吸烟)、妇女健康和以患者为中心的护理的健康风险直接相关。

DESCRIPTION (provided by applicant): We propose to assess the role of cardiovascular disease (CVD) risk estimation in veterans without cancer or other major illnesses and compare the utility of using US national guideline estimates from ATP4 versus VA-specific formulations developed from VISN 1 and VISN 7. The core variables that will be used include traditional risk factors such age, sex, race, blood pressure, smoking, cholesterol, HDL cholesterol and diabetes status. In addition, we propose to identify the best ways to assess CVD risk in veterans with diabetes mellitus and in veterans who have already experienced a CVD event. We will evaluate the precision and accuracy of the ATP4 estimating equations in the VA and separately develop CVD risk equations using ATP4 variables to evaluate the best approach to estimate CVD risk in veterans. This critical evaluation of the risk of CVD in veterans is aimed to provide effective and convenient risk assessment tools - that in the future could be incorporated into clinical care for outpatient veterans and has the potential to guide CVD preventive therapy within the VA so that resources can be aligned to intervene appropriately with cardiovascular preventive services in veterans at high risk for developing a future CVD event. This proposal has direct relevance to the health risks of risky behavior (cigarette smoking), women's health, and patient-centered care.