Multidisciplinary Training in Molecular Endocrinology

分子内分泌学多学科培训

• 批准号: 8914564
• 负责人: Richard M O'Brien
• 金额: $ 60.93万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-07-01 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8914564
• 关键词: Endocrinology; Molecular; Training; multidisciplinary

DESCRIPTION (provided by applicant): This proposal requests continued support for the Molecular Endocrinology Training Program (METP) at Vanderbilt University. Progress towards understanding and curing obesity, diabetes and many other diseases requires the training of the next generation of scientists with expertise in molecular endocrinology, the goal of this program. The METP comprises 30 faculty members in 6 basic science departments. Of this group 27 are established faculty with stable, well-funded programs and substantial training experience and 3 are new investigators; 5 of these preceptors are female, 1 is a minority and 1 is disabled. This preceptor group constitutes a unusually diverse and talented group of individuals whose work covers the spectrum of molecular endocrinology. These preceptors conduct research in the general areas of: 1) signal transduction 2) the hormonal regulation of gene expression, 3) metabolic regulation and 4) beta-cell development and function. The request for a steady state level of 8 predoctoral and 4 postdoctoral trainees is justified on the basis of the number, size and quality of the research programs directed by the preceptors and the Institutional commitment to continue the same level of trainee recruitment despite the tough economic climate. All METP trainees are appointed upon the advice of an Admissions Committee after being nominated by a preceptor. Postdoctoral trainees have a Ph.D. degree. Rigorous in depth research training is the focus of both the pre and postdoctoral training programs. However, the METP also ensures that all trainees receive a broad didactic education. Predoctoral training in the METP follows that received in the Interdisciplinary Graduate Program (IGP). The IGP recruits almost all predoctoral trainees in the biomedical sciences at Vanderbilt, provides a first year core curriculum, safety training and formal evaluation and career counseling programs. This centralized recruitment has considerably increased the number and quality of predoctoral students that enter Vanderbilt. After four laboratory rotations predoctoral students choose a preceptor for their thesis project and compete for METP support. The IGP and METP have been very successful in promoting diversity and both provide ongoing training in the Responsible Conduct of Research. All METP trainees attend an annual METP Day retreat and the Vanderbilt Diabetes Center (VDC) seminar series where they meet with visiting scientists. In conjunction with the Juvenile Diabetes Research Foundation the METP has recently initiated a novel strategy to increase the recruitment of disabled individuals, specifically undergraduates with type 1 diabetes, through the creation of a VDC funded Summer Diabetes Research Program. The METP has already successfully trained 153 scientists of whom 54 have already gone onto assume academic/pharmaceutical positions with another 34 trainees still in training.

描述（由申请人提供）：本提案要求继续支持范德比尔特大学的分子内分泌学培训计划（METP）。了解和治疗肥胖症，糖尿病和许多其他疾病的进展需要培养具有分子内分泌学专业知识的下一代科学家，这是该计划的目标。METP由6个基础科学系的30名教师组成。其中27人是具有稳定、资金充足的方案和丰富培训经验的教师，3人是新的研究人员;其中5人是女性，1人是少数民族，1人是残疾人。这组导师组成了一个异常多样化和有才华的个人群体，他们的工作涵盖了分子内分泌学的光谱。这些导师在以下一般领域进行研究：1）信号转导2）基因表达的激素调节，3）代谢调节和4）β细胞发育和功能。对8名博士前和4名博士后学员的稳定水平的要求是合理的，其依据是导师指导的研究项目的数量，规模和质量，以及尽管经济形势严峻，机构仍承诺继续招聘相同水平的学员。所有的METP学员都是在导师提名后，根据招生委员会的建议任命的。博士后培训生拥有博士学位。℃下严格的深入研究培训是博士前和博士后培训项目的重点。然而，教育和培训方案还确保所有受训人员接受广泛的教学教育。在METP的博士前培训如下，在跨学科研究生课程（IGP）收到。IGP几乎招募了范德比尔特生物医学科学的所有博士前实习生， 一年的核心课程，安全培训和正式评估和职业咨询计划。这种集中招生大大增加了进入范德比尔特的博士前学生的数量和质量。经过四次实验室轮换，博士前学生为他们的论文项目选择一位导师，并争取METP的支持。IGP和METP在促进多样性方面非常成功，并且都在负责任的研究行为方面提供持续的培训。所有METP学员参加每年的METP日务虚会和范德比尔特糖尿病中心（VDC）研讨会系列，在那里他们会见了来访的科学家。与青少年糖尿病研究基金会一起，METP最近发起了一项新的战略，通过创建VDC资助的夏季糖尿病研究计划，增加残疾人的招募，特别是1型糖尿病的本科生。METP已经成功培训了153名科学家，其中54人已经担任学术/制药职位，另有34名受训人员仍在接受培训。