Enhancing alternatives to eating in infancy

增强婴儿期饮食的替代方案

基本信息

批准号：
9196048
负责人：
Leonard H Epstein
金额：
$ 58.58万
依托单位：
STATE UNIVERSITY OF NEW YORK AT BUFFALO
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-08-01 至 2021-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9196048
关键词：
Adolescent Adult Aftercare Age Animal Experimentation Attention Behavior Biological Birth Body mass index Child Development Dietary intake Disease Eating Energy Intake Energy Metabolism Environment Equilibrium Food Goals Group Meetings Home environment Human Infant Infant Development Intervention Laboratories Lead Learning Length Long-Term Effects Maintenance Measurement Motivation Music Obesity Outcome Overweight Parents Phase Pilot Projects Placebos Play Preventive Intervention Psychological reinforcement Randomized Randomized Controlled Trials Research Risk Sampling Self Administration Structure Testing Time Treatment Efficacy Weight Weight Gain Work arm behavioral economics cognitive enhancement drug development energy balance environmental enrichment for laboratory animals falls infancy meetings novel strategies obesity in children obesity prevention prevent programs prospective reinforcer

项目摘要

ABSTRACT Obesity is a disorder of positive energy balance in which energy intake exceeds energy expenditure. The motivation to eat is a basic human need, which is present at birth. One factor that may lead to increased energy intake is the imbalance between the motivation to eat and the motivation to engage in other behaviors. The motivation to eat versus engaging in other behaviors can be operationalized as the relative reinforcing value of eating versus alternative behaviors. A strong motivation to eat instead of engaging in alternative behaviors has been related to increased energy intake in adults. The motivation to eat is cross-sectionally and prospectively related to obesity in children, adolescents, and adults, and cross-sectionally related to weight status in infants. Shifting the balance from high motivation to eat to increased motivation to engage in alternative behaviors can reduce energy intake, and may be protective against weight gain. We have recently shown that a structured program to enhance music engagement in infants who are strongly motivated to eat can shift their choice from food to music. The goal of this study is to expand on this preliminary research and examine long-term effects of this intervention in infants who are highly motivated to eat. We are proposing to randomize 92 healthy infants who are high in food reinforcement to a music enhancement program versus an attention placebo play date and assess changes in food/non-food reinforcement, infant energy intake, weight for length z-score, and enriched home environment, and follow the development of these infants over a 24 month period. We predict that the music program, in comparison to the control play date, will result in a shift in choice from a motivation to eat to a motivation to engage in alternatives to eating (Specific Aim 1) and thus reduce energy intake (Specific Aim 1a), lower weight for length z-score (zWFL) (Specific Aim 2), and create a more enriched home environment (Specific Aim 3) at each measurement interval. We propose that enhancing the motivation to engage in alternatives to eating represents a novel approach to obesity prevention, and these interventions are easily implemented and scalable.

抽象的肥胖是一种积极能量平衡的疾病，其中能量摄入超过了能量消耗。这进食动机是人类的基本需求，出生时存在。可能导致增加的一个因素能量摄入是饮食动机与参与其他行为的动机之间的失衡。饮食的动机与从事其他行为的动机可以作为相对增强饮食与替代行为的价值。强大的进食动机而不是替代行为与成年人的能量摄入量增加有关。吃的动机是横截面前瞻性与儿童，青少年和成人的肥胖有关，以及与体重的横截面有关婴儿的状态。将平衡从高动力转变为进食的动力增加替代行为可以减少能量摄入量，并且可以防止体重增加。我们最近有表明，一个结构化计划，以增强有力进食的婴儿的音乐参与度可以将他们的选择从食物转变为音乐。这项研究的目的是扩展这项初步研究和检查这种干预措施对高度动力进食的婴儿的长期影响。我们正在提议随机分配92名健康的婴儿，他们的食物增强率很高，以提高音乐增强计划注意安慰剂游戏日期并评估食物/非食品增强，婴儿能量摄入，体重的变化为z得分长度和丰富家庭环境，并跟随这些婴儿在24中的发展月期。我们预测音乐节目与控制日期相比将导致从饮食的动力到参与饮食替代品的动力（特定目标1），从而选择减少能量摄入量（特定目标1A），降低长度z得分（ZWFL）（特定AIM 2）的重量，并创建在每个测量间隔内更丰富的家庭环境（特定目标3）。我们提出了这一点增强参与饮食替代品的动机是一种新颖的肥胖方法预防，这些干预措施很容易实施和扩展。