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Image Data Acquisition, Analysis, and Modeling Core

图像数据采集、分析和建模核心

基本信息

批准号：
9085409
负责人：
SHENG-KWEI SONG
金额：
$ 20.43万
依托单位：
WASHINGTON UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-09-25 至
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/9085409
关键词：
Acute Address Affect Agar Animal Model Animals Autopsy Axonal Transport Back Biological Markers Biopsy Blood - brain barrier anatomy Brain Cell Polarity Cells Cellularity Central Nervous System Diseases Chronic Clinical Trials Communities Computer software Conflict (Psychology)Data Data Analyses Decision Making Demyelinations Development Diagnostic Diffusion Diffusion Magnetic Resonance Imaging Disease Edema Endothelial Cells Ensure Experimental Autoimmune Encephalomyelitis Experimental Designs Extravasation Funding Gel Gold Histology Human Human Resources Image Immunohistochemistry Individual Infiltration Inflammation Life Magnetic Resonance Imaging Manganese Manuals Maps Measurement Measures Methods Modeling Multiple Sclerosis Mus Myelin Myelin Sheath Neuraxis Optic Nerve Outcome Measure Pathogenesis Pathology Patient Monitoring Patients Procedures Process Program Research Project Grants Protocols documentation Regulation Reporting Resolution Sampling Services Signal Transduction Spinal Cord Staging Staining method Stains Testing Time Tissues Translating Treatment Efficacy Validation Visual Acuity Water Work axon injury base data acquisition data management design head-to-head comparison human subject imaging biomarker imaging modality improved in vivo in vivo imaging meetings member multiple sclerosis patient neuropathology novel therapeutics prevent professor spectrograph success tissue phantom tool white matter white matter injury

项目摘要

Objectives: The Image Data Acquisition, Analysis, and Modeling Core will be responsible for (1) supporting the MRI experimental design and execution for all projects; (2) developing an objective MRIimmunohistochemistry validation method; (3) improving data acquisition efficiency; (4) streamlining postprocessing procedures; and (5) participating in data interpretation and dissemination of all MRI results. Core C will explore the possibility of using T2 relaxometry, myelin water imaging, to detect and quantify multiple pathologies in CNS white matter. Core Services: Core C is specifically designed to support all Projects of this program project grant, not a general purposed service core unit to the community. Outside studies relevant to the scope of this PPG will be considered after the approval of Executive Committee (Drs. Cross, Klein, Song and Trinkaus). It is the responsibility of Core C to perform all necessary tasks assuring the success of all MRI measurements. Decision-Making: During the planning of this renewal of this PPG, members of the executive committee have met and discussed regularly on specific tasks of Core C. Thus, the Core Co-directors Song and Kim will work closely with all Project and Core personnel to perform the proposed MRI studies and modify if necessary as projects progress. Any conflict in experimental execution will first be resolved between the involved Project/Core directors and Song/Kim team. Any unresolved conflict will be resolved through the PPG Executive Committee. The data interpretation and dissemination will be conducted by all involved Project/Core personnel, submitting to Executive Committee for final approval.

目标：图像数据采集，分析和建模核心将负责(1)支持