Health Promotion for Positives: A Randomized Trial with HIV Positive Black Men

积极健康促进：艾滋病毒阳性黑人男性的随机试验

• 批准号: 8985689
• 负责人: JOHN BARTON JEMMOTT
• 金额: $ 39.91万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-03-21 至 2018-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8985689
• 关键词: AIDS prevention; AIDS-Related Opportunistic Infections; Adherence; Affect; African American; Age; Aging; Anti-Retroviral Agents; Applications Grants; Attention; Behavior; Behavioral; Blood Pressure; Body mass index; Budgets; Cardiovascular Diseases; Centers for Disease Control and Prevention (U.S.); Chronic; Chronic Disease; Colon Carcinoma; Comorbidity; Complement; Computer Assisted; Control Groups; Couples; Data; Diabetes Mellitus; Diet; Evidence based intervention; Expectancy; Future; General Population; Guidelines; HIV; HIV Infections; HIV Seropositivity; Health; Health Promotion; Health behavior; Highly Active Antiretroviral Therapy; Hour; Hypertension; Individual; Intervention; Interview; Kidney Diseases; Life; Link; Long-Term Effects; Malignant Neoplasms; Malignant neoplasm of prostate; Measures; Mediating; Mediator of activation protein; Medical Records; Morbidity - disease rate; Outcome; Participant; Patient Self-Report; Persons; Physical Fitness; Physical activity; Physiological; Prevention; Prostate; Randomized; Randomized Controlled Trials; Research; Risk; Screening for Prostate Cancer; Self Efficacy; Testing; Time; Treatment Efficacy; United States; Vulnerable Populations; Waist-Hip Ratio; Walking; base; behavior change; comparative efficacy; design; effective therapy; efficacy testing; empowered; experience; fitness; fruits and vegetables; health disparity; high risk; innovation; interest; man; men; mortality; post intervention; primary outcome; racial health disparity; randomized trial; response; screening; sex; social cognitive theory; successful intervention; theories; waist circumference

PROJECT SUMMARY: This application is in response to RFA-MD-12-001, "NIMHD Health Disparities Research (R01)." African American men who are infected with HIV are living longer and are being impacted by the same chronic diseases that affect the general population of African American men over 40. To be sure, African American men, in general, have disproportionately high rates of cardiovascular disease, hypertension, diabetes, kidney disease, and cancer, particularly prostate and colon cancer. However, HIV infection is associated with an increased risk for co-morbidity from chronic diseases. This increased risk is heightened by HIV infection, but also its treatment with certain agents used in highly active antiretroviral therapy (HAART) combinations. Many of these chronic illnesses have behavioral components-risk is influenced by what people do and don't do, their diet, and the amount of physical activity they get. Although the high risk for multiple behavior-linked chronic diseases among HIV-positive individuals has been recognized, there is a lack of evidence-based intervention specifically tailored to their needs. Hence, the broad objective is to reduce the risk of chronic diseases among HIV positive African American men. The Specific Aims are to test the efficacy of a theory- based, contextually appropriate health promotion intervention in inducing positive changes in behaviors linked to risk of chronic diseases among HIV positive African American men age 40 years or older and to identify the theoretical variables that mediate its efficacy. The study will utilize a randomized controlled trial. The participants will be 384 African American HIV positive men age 40 or older who are receiving HAART for HIV. The men will be randomized to a theory-based contextually appropriate health promotion intervention that involves three, 3-hour weekly intervention sessions or an attention-control group. The health promotion intervention will be an adaptation of an intervention based on social cognitive theory integrated with formative research and found to be efficacious in increasing adherence to 5-a-Day diet and physical activity guidelines and prostate cancer screening guidelines in the applicants' preliminary studies. Data will be collected at baseline, immediately post, 3, 6 and 12 months post intervention, which will permit assessment of the short- term and long-term effects of the intervention and whether the intervention's efficacy varies over time. Audio computer-assisted self-interviewing will be used to assess self-reported adherence to physical activity guidelines, 5-a-Day fruit and vegetable guidelines, prostate screening guidelines, and colon cancer screening guidelines and theoretical mediators of behavior change. Objective outcomes will include health-related fitness (6-minute walk test, 1-minute push-up test, 1-minute sit-up test, sit-and-reach test), physiological variables (blood pressure, body mass index, waist circumference, and waist-hip ratio), and prostate and colon cancer screening based on medical record review.

项目总结： 本申请是对RFA-MD-12-001，“NIMHD健康差距研究(R01)”的响应。非洲 感染艾滋病毒的美国男性寿命更长，并受到同样慢性疾病的影响. 影响40岁以上非裔美国人普通人口的疾病。当然，非裔美国人 一般来说，男性患心血管疾病、高血压、糖尿病、肾脏疾病的几率高得不成比例。 疾病和癌症，特别是前列腺癌和结肠癌。然而，艾滋病毒感染与一种 增加慢性病合并发病的风险。这种增加的风险因艾滋病毒感染而增加，但 此外，它还与高效抗逆转录病毒疗法(HAART)组合中使用的某些药物一起治疗。许多 这些慢性病中有行为成分--风险受人们做什么和不做什么的影响， 他们的饮食，以及他们得到的体力活动量。尽管与多种行为相关的高风险 HIV阳性个体慢性病已被认识，缺乏证据支持 专门为他们的需求量身定制的干预。因此，总体目标是降低慢性病的风险。 艾滋病病毒阳性的非洲裔美国男性中的疾病。具体目的是测试一种理论的有效性-- 基于背景的健康促进干预，以诱导相关行为的积极变化 了解40岁或以上HIV阳性的非洲裔美国男性罹患慢性病的风险，并确定 调节其疗效的理论变量。这项研究将采用随机对照试验。这个 参与者将是接受HAART治疗艾滋病毒的384名40岁或40岁以上的非裔美国艾滋病毒阳性男子。 这些男性将随机接受基于理论的背景适当的健康促进干预 包括每周三次、每次3小时的干预会议或一个注意力控制组。健康促进 干预将是基于社会认知理论和形成主义相结合的干预的改编 研究发现，这能有效地提高人们对每天5天饮食和体力活动指南的遵守程度 和前列腺癌筛查指南在申请者的初步研究中。数据将在以下位置收集 基线，即干预后、干预后3、6和12个月，这将允许评估短期- 干预的长期和长期效果，以及干预的效果是否随时间而变化。音频 将使用计算机辅助的自我访谈来评估自我报告的对体育活动的遵守情况 指南、每日5种水果和蔬菜指南、前列腺癌筛查指南和结肠癌筛查 行为改变的指导方针和理论中介者。客观结果将包括与健康相关的健康状况 (6分钟步行试验、1分钟俯卧撑试验、1分钟仰卧起坐试验、仰卧起坐试验)、生理变量 (血压、体重指数、腰围和腰臀比)，以及前列腺癌和结肠癌 根据病历审查进行筛查。

项目成果

Reasoned Action Approach Correlates of Physical Activity Among African American Men Living With HIV: A Cross-Sectional Study.

合理的行动方法与感染艾滋病毒的非洲裔美国男性的身体活动相关：一项横断面研究。

• DOI: 10.1097/jnc.0000000000000196
• 发表时间: 2021
• 期刊: The Journal of the Association of Nurses in AIDS Care : JANAC
• 作者: Kelly,Terri-Ann;Woko,Chioma;Jemmott,LorettaS;Icard,Larry;Chittamuru,Deepti;Jemmott3rd,JohnB
• 通讯作者: Jemmott3rd,JohnB