Affordable wireless neural recording for mice

 描述(申请人提供)：标题：Jaga Penny：负担得起的小鼠无线神经记录多通道神经记录已成为探索复杂神经电路组织的强大工具。然而，要从植入的无拘无束、清醒和行为正常的动物，特别是那些小到老鼠的动物进行记录，需要一个非常轻、高质量的无线传输系统。典型的神经科学家既没有专业知识，也没有预算来实施目前市场上复杂的无线记录技术。在所有神经科学中，老鼠是唯一最常用的动物模型。基于许多“基因敲除”小鼠的临床测试和翻译实验将受益于用于神经记录的无缆活体小鼠行为实验。为了提高无线多通道神经工程技术对更广泛的神经科学界的可及性，JAGA-HI Inc.建议开发一种极其用户友好、交钥匙、价格实惠、16通道、高保真的“即插即用”无线记录系统Jaga_Penny。像我们的第一款产品JAGA16一样，我们的Jaga Penny将是一个可拆卸的微型头盔放大/传输系统。实际上，所有的记录硬件都集中在一个小型的自给自足的设备中，在实验期间临时连接到头骨上。这种方法完全不需要其他外部设备，因为它使用板载放大器/滤波器/微处理器进行信号调节，并将数字化的神经数据/刺激命令直接传输到附近的PC。使用现成的低成本高级芯片组实现高技术精度，使用户能够以非常实惠的价格(4.5-6000美元)购买该设备，这远远低于市场上现有的电生理解决方案。

 DESCRIPTION (provided by applicant): Title: JAGA Penny: Affordable wireless neural recording for mice Multi-channel neural recording has emerged as a powerful tool for probing the organization of complex neural circuitry. However, to record from implanted non- restrained, awake and behaving animals, especially those as small as mice, requires a very lightweight, high quality wireless transmission system. The typical neuroscientist has neither the expertise, nor the budget to implement the complex wireless recording technologies currently on the market. Mice are the single most used animal model in all of neuroscience. Clinical testing and translational experiments based on many "knock-out" mice will benefit from cable-free in vivo mice behavior experiments for neural recording. To improve accessibility of wireless multi-channel neural engineering technology to the wider neuroscience community for mice, Jinga-hi Inc. proposes to develop an extremely user-friendly, turnkey, affordable, 16-channel, high fidelity "plug and play" wireless recording system called the JAGA_Penny. Like our first product, The JAGA16, our JAGA penny will be a removable, miniaturized ,head-mounted amplification/transmission system. Effectively, all recording hardware is concentrated into a small self-contained device temporarily connected to the skull during an experiment. This approach requires absolutely no other external equipment because it uses on-board amplifier/filter/microprocessor for signal conditioning and transmits digitized neural data/stimulation commands directly to a nearby PC. Use of off-the-shelf low-cost advanced chipsets for high technical precision allows users to purchase the device at a very affordable price ($4.5-6K), which is far less than existing electrophysiology solutions already on the market.