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中文摘要
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项目摘要 小鼠提供了强大的遗传模型系统,因此是神经科学中最常用的动物模型。尽管 无线记录的潜在好处(更灵活、更安全、更自然的体内神经记录),采用 由于神经科学界对小鼠的无线记录对于更广泛的神经科学界来说进展缓慢, 使轻型设备能够记录/传输高保真/多通道/高带宽信号的工程复杂性 合理的录音时间。目前市场上的无线神经记录设备要么是基于模拟的, 传输,贸易低计数/低通道更长的时间,太重的鼠标或仍然太昂贵。没有提供 同步记录和电刺激,可完全集成到行为软件中, 老鼠还在。 Jinga-hi,Inc.的贾加便士(作为最终产品)将是独一无二的市场上作为一个紧凑型(硬币大小的所有在一个), 经济实惠(5.5 - 7.5K美元),高品质,多通道无线系统,能够同时记录神经(高达32通道) 以及用于小鼠的高频带信号(单位记录)和低频带信号的刺激(高达16/32CH)。此外,本发明还提供了一种方法, 我们易于使用和可扩展(4 - 8设备在同一时间)的系统将完全集成到现有的领先的 行为和视频/事件跟踪软件。我们预计JAGA Penny将广泛协助 神经科学家在更自然的体内环境中结合电生理学和行为实验的努力。
英文摘要
Project Summary Mice offer a powerful genetic model system, thus are the single most used animal model in neuroscience. Despite potential benefits of wireless recording (more flexible, safer, and more natural in vivo neural recording), adoption of wireless recording in the neuroscience community for mice for a wider neuroscience community had been slow, due to the engineering complexity to enable a lightweight device record/transmit high fidelity/multichannel/high bandwidth signals for reasonable recording hours. Wireless neuro recording devices on the market are currently either analog based transmission, trade low count/low channel for longer hours, too heavy for mice or still too expensive. None provide simultaneous recording and electrical stimulation for high channels with full integration into behavioral software ideal for mice yet. Jinga-hi, Inc.'s JAGA Penny (as a final product) will be unique on the market as a compact (coin-sized all in one), affordable ($5.5-7.5K), high quality, multichannel wireless system capable of simultaneous neural recording (up to 32 ch) and stimulation (up to 16/32 ch) for high band signals (unit recording) as well as low band signals for mice. In addition, our easy to use and scalable (4-8 devices at the same time) system will be fully integrated into available leading behavioral and video/event-tracking software on the market. We anticipate that JAGA Penny will widely assist neuroscientists' efforts in combining electrophysiology and behavior experiments in a more natural in vivo environment.
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Affordable wireless neural recording for mice
  • 批准号:
    9138954
  • 项目类别:
  • 资助金额:
    $22.02万
  • 财政年份:
    2016
  • 负责人:
    Mee H Choi
  • 依托单位:
Autophosphorylation of CaMKII in Neural Signal Transduction
Autophosphorylation of CaMKII in Neural Signal Transduction
Autophosphorylation of CaMKII in Neural Signal Transduction
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