2015 CRTI Summer Workshop

 描述（申请人提供）：美国血液学会（ASH）临床研究培训研究所（CRTI）成立于2003年，培养研究员和初级教师，在血液学的所有领域开展以患者为导向的临床研究，包括血液恶性肿瘤（白血病，淋巴瘤，多发性骨髓瘤，骨髓增生异常综合征，骨髓增生性肿瘤）和非恶性血液学（出血和凝血障碍以及红和白色血细胞疾病）。拥有一支准备进行这项研究的医生队伍对于将实验室和临床前研究的发展转化为患者和人群的护理至关重要。CRTI是一个为期一年的计划，包括为期一周的夏季研讨会，持续的指导，和两个后续会议。此应用程序请求支持2015年CRTI夏季研讨会，这是“启动”活动的20名研究员和初级教师谁将在该计划的培训。夏季研讨会的目标是为参与者提供他们的研究建议的反馈，在参与者和教师之间建立专业网络，并确定谁将在接下来的一年中与参与者一起工作的导师，以确保在CRTI经验的投资得到充分利用。夏季研讨会包括至少尽可能多的教师作为参与者。它的特点是在血液学，临床试验设计，和生物统计学的国家和国际专家。为期一周的计划包括互动教学会议，小组突破，以及非正式互动的时间。ASH采取多管齐下的战略，以确保妇女和少数民族参与者在参与者和教师群体中的适当代表性。对参与者的战略包括初步外联，以确保尽可能多的女性和少数族裔申请人，以及在最后甄选过程中重点讨论多样性目标。女性和少数民族教师也积极确定从过去的计划参与者，并通过过去和现在的CRTI教师的网络。参加者对CRTI夏季讲习班进行评价。2014年CRTI夏季研讨会后评估的结果表明，该活动是成功的导师提供了非常有益的建议，拟议的研究计划（95%的参与者）。整个计划也得到了系统的评估。在2010年调查的2003-2009年的140名CRTI参与者中，87%的人表示他们成功地建立了以患者为导向的临床研究，85%的人认为自己是临床研究者，90%的人正在进行研究作为他们当前工作的一部分。大约40%的人与CRTI的导师进行了持续的合作。CRTI的参与者非常富有成效，其中有1，000多份同行评审的出版物，170本书的章节和100篇评论文章。他们作为主要研究者获得了78项NIH赠款。

 DESCRIPTION (provided by applicant): The American Society of Hematology (ASH) Clinical Research Training Institute (CRTI) was initiated in 2003 and prepares fellows and junior faculty to conduct patient-oriented clinical research in all areas of hematology, including the hematological malignancies (leukemia, lymphoma, multiple myeloma, myelodysplastic syndromes, myeloproliferative neoplasms) and non-malignant hematology (bleeding and clotting disorders and diseases of red and white blood cells). Having a physician workforce prepared to conduct this research is critical to converting developments in laboratory and pre-clinical research to the care of patients and populations. CRTI is a year-long program that includes a week-long Summer Workshop, ongoing mentoring, and two follow-up meetings. This application requests support for the 2015 CRTI Summer Workshop, which is the "kick-off" event for the 20 fellows and junior faculty who will be trained in the program. The goals of the Summer Workshop are to provide participants feedback on their research proposals, build professional networks among the participants and faculty, and identify mentors who will work with the participants over the course of the following year to ensure the investment in the CRTI experience is well utilized. The Summer Workshop includes at least as many faculty instructors as participants. It features national and international experts in hematology, clinical trial desig, and biostatistics. The week-long program includes interactive didactic sessions, small group breakouts, and time for informal interactions. ASH undertakes a multi-pronged strategy to ensure the appropriate representation of women and minority participants in both the participant and faculty groups. The strategy for participants includes initial outreach to secure the largest possible pool of female and minority applicants as well as focused discussions about diversity goals during the finalist selection process. Female and minority faculty are likewise actively identified from among past program participants and through the network of past and current CRTI faculty. The CRTI Summer Workshop is evaluated by the participants. Results of the 2014 CRTI Summer Workshop post-workshop evaluation indicate the event was successful in mentors providing very helpful recommendations on the proposed research plans (95% of participants). The entirety of the program is also systematically evaluated. Of the 140 CRTI participants from 2003-2009 surveyed in 2010, 87% stated they had been successful in establishing a patient-oriented clinical research study, 85% considered themselves to be clinical investigators, and 90% were conducting research as part of their current jobs. Approximately 40% had an ongoing collaboration with a CRTI mentor. CRTI participants have been extremely productive, with over 1,000 peer-reviewed publications, 170 book chapters, and 100 review articles amongst them. They have earned 78 NIH grants as principal investigators.