2015 CRTI Summer Workshop

 描述(申请人提供)：美国血液学会(ASH)临床研究培训研究所(CRTI)成立于2003年，培养研究员和初级教员，在血液学的所有领域进行以患者为导向的临床研究，包括血液系统恶性肿瘤(白血病、淋巴瘤、多发性骨髓瘤、骨髓增生异常综合征、骨髓增殖性肿瘤)和非恶性血液病(出血和凝血障碍以及红细胞和白细胞疾病)。拥有一支准备进行这项研究的医生队伍对于将实验室和临床前研究的发展转变为对患者和人群的护理至关重要。CRTI是一个为期一年的项目，包括为期一周的夏季研讨会、持续的指导和两个后续会议。此应用程序请求为2015 CRTI夏季研讨会提供支持，该研讨会是将接受该计划培训的20名研究员和初级教员的“启动”活动。暑期研讨会的目标是向参与者提供他们的研究建议的反馈，在参与者和教职员工之间建立专业网络，并确定在接下来的一年中与参与者合作的导师，以确保对CRTI体验的投资得到充分利用。暑期工作坊的教员人数至少与参与者一样多。它以血液学、临床试验设计和生物统计学方面的国内和国际专家为特色。为期一周的课程包括互动授课、小组突破和非正式互动时间。ASH采取了一项多管齐下的战略，以确保妇女和少数群体参与者在参与者和教职员工群体中都有适当的代表性。参与者的战略包括初步外联，以确保尽可能多的女性和少数族裔申请者，以及在最终入围者选择过程中重点讨论多样性目标。女性和少数族裔教职员工也同样积极地从过去的项目参与者中以及通过CRTI过去和现在的教职员工网络进行识别。CRTI暑期研讨会由与会者进行评估。2014年CRTI夏季研讨会的研讨会后评估结果表明，活动成功地得到了导师的支持，为拟议的研究计划提供了非常有帮助的建议(95%的参与者)。对整个项目也进行了系统的评估。在2010年接受调查的140名2003-2009年CRTI参与者中，87%的人表示他们成功地建立了以患者为中心的临床研究研究，85%的人认为自己是临床研究人员，90%的人将研究作为当前工作的一部分。大约40%的人与CRTI导师进行了持续的合作。CRTI的参与者非常富有成效，有1000多本同行评议的出版物，170本书的章节，其中有100篇评论文章。作为首席研究员，他们已经获得了78项NIH拨款。

 DESCRIPTION (provided by applicant): The American Society of Hematology (ASH) Clinical Research Training Institute (CRTI) was initiated in 2003 and prepares fellows and junior faculty to conduct patient-oriented clinical research in all areas of hematology, including the hematological malignancies (leukemia, lymphoma, multiple myeloma, myelodysplastic syndromes, myeloproliferative neoplasms) and non-malignant hematology (bleeding and clotting disorders and diseases of red and white blood cells). Having a physician workforce prepared to conduct this research is critical to converting developments in laboratory and pre-clinical research to the care of patients and populations. CRTI is a year-long program that includes a week-long Summer Workshop, ongoing mentoring, and two follow-up meetings. This application requests support for the 2015 CRTI Summer Workshop, which is the "kick-off" event for the 20 fellows and junior faculty who will be trained in the program. The goals of the Summer Workshop are to provide participants feedback on their research proposals, build professional networks among the participants and faculty, and identify mentors who will work with the participants over the course of the following year to ensure the investment in the CRTI experience is well utilized. The Summer Workshop includes at least as many faculty instructors as participants. It features national and international experts in hematology, clinical trial desig, and biostatistics. The week-long program includes interactive didactic sessions, small group breakouts, and time for informal interactions. ASH undertakes a multi-pronged strategy to ensure the appropriate representation of women and minority participants in both the participant and faculty groups. The strategy for participants includes initial outreach to secure the largest possible pool of female and minority applicants as well as focused discussions about diversity goals during the finalist selection process. Female and minority faculty are likewise actively identified from among past program participants and through the network of past and current CRTI faculty. The CRTI Summer Workshop is evaluated by the participants. Results of the 2014 CRTI Summer Workshop post-workshop evaluation indicate the event was successful in mentors providing very helpful recommendations on the proposed research plans (95% of participants). The entirety of the program is also systematically evaluated. Of the 140 CRTI participants from 2003-2009 surveyed in 2010, 87% stated they had been successful in establishing a patient-oriented clinical research study, 85% considered themselves to be clinical investigators, and 90% were conducting research as part of their current jobs. Approximately 40% had an ongoing collaboration with a CRTI mentor. CRTI participants have been extremely productive, with over 1,000 peer-reviewed publications, 170 book chapters, and 100 review articles amongst them. They have earned 78 NIH grants as principal investigators.