Multispectral near-infrared imaging of dental caries in children

儿童龋齿的多光谱近红外成像

基本信息

批准号：
9230389
负责人：
Eric J Seibel
金额：
$ 14.69万
依托单位：
UNIVERSITY OF WASHINGTON
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-03-01 至 2018-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9230389
关键词：
12 year old Address Adolescent Adult Age Alaska Native Algorithms Area Bitewing Radiography Caliber Child Childhood Chronic Chronic Disease Clinic Clinical Collection Color Communicable Diseases Country Dental Dental Care Dental Enamel Dental Technicians Dental caries Dentists Detection Devices Diagnosis Diagnostic Diagnostic radiologic examination Endoscopes Environment Equipment Exposure to Fiber Goals Hand Health Histology Image Imaging Device In Vitro Industry Ions Lasers Lead Lesion Letters Light Lighting Location Measurement Measures Metals Methods Monitor Native-Born Neighborhoods Optics Oral cavity Oral health Orthodontic Pain Palpation Parents Pediatric Dentistry Pediatric Hospitals Persons Pilot Projects Population Population Group Positioning Attribute Preschool Child Preventive Preventive measure Procedures Research Resolution Risk Roentgen Rays Running Rural Scanning Severities Surface Technology Telecommunications Telemedicine Testing Therapeutic Three-Dimensional Imaging Time Tissues Tooth Diseases Tooth structure Training Universities Visible Radiation Visual Washington Work accurate diagnosis base contrast imaging cost detector efficacy study health care disparity health disparity high resolution imaging imaging modality in vivo instrument nano novel therapeutics operation optical fiber optical imaging portability prototype public health relevance quantitative imaging sensor transmission process underserved minority

项目摘要

DESCRIPTION (provided by applicant): Dental caries is one of the most common chronic infectious diseases in the world. The occlusal (biting surface) and interproximal (between teeth) areas are where there need for quantitative imaging of tooth decay and depth of cracks in the USA. In addition a majority of the caries load in USA is carried by different groups, such as Alaska Native people who have many times the national rate of tooth decay. Health care disparities in this population are exacerbated by rural remoteness. The average number of dental fillings per Alaskan Native person is double that of urban dwellers. To provide safe, high-quality dental care in these remote areas, an x- ray replacement is desired which provides high-resolution optical images of cracks and decay deep within teeth that does not require ionizing x-ray radiation. The current problem is that the optimal wavelengths of infrared light (1310 and 1460 nm) that can be used to see decay in teeth, do not have small high-resolution cameras for pediatric clinical use. Thus, an alternative method of forming infrared images will be developed and tested that produces the highest contrast of the lesion, which is scanning laser light either i transmission, reflection, and in a right-angle configuration (for example, scan the occlusal surface and detect above the gum line). The smallest laser-based imaging device has been developed at the University of Washington (UW), being the diameter of a round toothpick (1.2-mm) while producing high-quality video images at multiple wavelengths. The scanning fiber endoscope (SFE) technology has been tested by Dr. Joel Berg in children at The Center for Pediatric Dentistry with shared administration from UW Pediatric Dentistry and Children's Hospital, Seattle, WA. Although this device used visible light for testing the health of the enamel the change to infrared is straightforward, allowing much deeper imaging of cracks and carious lesions using optimal laser wavelengths for high-contrast transmittance and reflectance imaging. The small size of the scanner allows the two imaging modes to run concurrently if needed to find the extent of a crack, maximum depth of caries, and even total volume of caries under surveillance with non-surgical medicinal therapies. The hand piece will be smaller than any bitewing radiographic sensor used in children now, while providing new features of imaging during restorative work, possibly under tele-medicine conditions. The SFE technology is fundamentally low in cost because it uses laser and detectors that are fully developed in the telecommunications industry. The low- power scanned laser light imaging can be made portable and carries no significant risks. This project will fabricate a prototype device, determine its optimal imaging modes (wavelength &configuration), develop new 3D imaging algorithms, test with extracted teeth and verify with a pilot study with children 6 to 12 years of age.

描述（由适用提供）：龋齿是世界上最常见的慢性传染病之一。咬合（咬咬）和二异二（牙齿之间）区域是美国对牙齿腐烂和裂纹深度进行定量成像的地方。此外，美国的大多数龋齿负荷都是由不同群体（例如阿拉斯加土著人民）承担的，他们的蛀牙率很多。该人群中的医疗保健差异因粗糙的偏僻而加剧。每个阿拉斯加本土人的牙科填充物的平均数量是城市居民的两倍。为了在这些偏远地区提供安全，高质量的牙科护理，需要进行X射线置换，该X射线更换提供了裂纹的高分辨率光学图像和牙齿深处的腐烂，这不需要电离X射线辐射。目前的问题是，可用于在牙齿中腐烂的红外光的最佳波长（1310和1460 nm），没有小的高分辨率摄像头用于小儿临床使用。这是一种形成红外图像的替代方法，并测试产生最高的病变对比度，即扫描激光i i i i i tromange，反射和右角构型（例如，扫描咬合表面并在牙龈线上检测）。最小的基于激光的成像装置是在华盛顿大学（UW）开发的，它是圆形牙签（1.2毫米）的直径，同时在多个波长的情况下生成高质量的视频图像。扫描纤维内窥镜（SFE）技术已由乔尔·伯格（Joel Berg）博士在小儿牙科中心的儿童中进行了测试，以及西澳州西雅图市西雅图市西雅图市西雅图州立大学儿科牙科和儿童医院的共同行政。尽管该设备使用可见光来测试搪瓷的健康，但对红外的变化是直接的，可以使用最佳的激光波长对裂纹和龋齿水平进行更深入的成像，以进行高对比度的传播和反射率成像。扫描仪的小尺寸允许两种成像模式在需要时同时运行，以找到裂缝的程度，最大的龋齿深度，甚至是通过非手术医学疗法进行监视的龋齿总量。该手部件将比现在在儿童中使用的任何咬合射线照相传感器小，同时在远程医疗条件下提供了恢复性工作期间成像的新功能。 SFE技术的成本基本低，因为它使用了电信行业中完全开发的激光和探测器。低功率扫描激光灯光成像可以使其便携，并且没有明显的风险。该项目将制造一个原型设备，确定其最佳成像模式（波长和配置），开发新的3D成像算法，用拔牙测试并通过6至12岁的儿童进行试验研究。