Clinical Core

临床核心：摘要/摘要： 该计划项目拨款(PPG)的临床核心是 负责所有参加PPG的参与者的认知和临床评估。《临床》 CORE协调并进行神经心理测试、神经学检查、收集病史 数据，管理抑郁症状问卷，并完成关于水平和评级的访谈 参与者的日常运作情况。此信息用于进行认知诊断分类 在衰老中，特别是正常认知与轻度认知障碍与痴呆症。临床核心 通过多学科共识会议分配诊断类别，该会议在两个月内组织 每周一次。诊断类别和认知测量由项目1、2、3和4用于初始 研究筛选和作为PPG目标中的关键认知结果。临床核心将所有 将认知和临床数据收集到成像、方法和统计核心，并协助 将临床数据与神经影像数据合并。最后，临床核心将招聘和协调新的 支持项目3的尸检案例。

Clinical Core: Summary/Abstract: The Clinical Core of the Program Project Grant (PPG) is responsible for cognitive and clinical evaluations for all participants enrolled in the PPG. The Clinical Core coordinates and conducts neuropsychological testing, neurological exams, collects medical history data, administers depression symptom questionnaires, and completes interviews about and rates levels of daily functioning of participants. This information is used to make cognitive diagnostic classifications in aging, specifically normal cognition vs. mild cognitive impairment vs. dementia. The Clinical Core assigns diagnostic categories via a multidisciplinary consensus conference, which it organizes on a bi- weekly basis. Diagnostic categories and cognitive measures are used by Projects 1, 2, 3, and 4 for initial study screening and as key cognitive outcomes in the Aims of the PPG. The Clinical Core transfers all cognitive and clinical data collected to the Imaging, Methodology and Statistics Core and assists in merging clinical data with neuroimaging data. Finally the Clinical Core will recruit and coordinate new autopsy cases in support of Project 3.